Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ABC99 is a selective irreversible inhibitor of the wnt-deacylating enzyme. ABC99 inhibited NOTUM (IC50: 13 nM). It also showed excellent selectivity across the serine hydrolase family.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 175.00 | |
5 mg | In stock | $ 372.00 | |
10 mg | In stock | $ 556.00 | |
25 mg | In stock | $ 896.00 | |
50 mg | In stock | $ 1,220.00 | |
100 mg | In stock | $ 1,650.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 373.00 |
Description | ABC99 is a selective irreversible inhibitor of the wnt-deacylating enzyme. ABC99 inhibited NOTUM (IC50: 13 nM). It also showed excellent selectivity across the serine hydrolase family. |
In vitro | ABC99 (0.1~10 μΜ; 2 hours; SW620 cells) inhibits NOTUM in a concentration-dependent manner and preserves Wnt-3A activity in the presence of NOTUM in a concentration-dependent manner[1]. |
Synonyms | ABC 99, ABC-99 |
Molecular Weight | 456.88 |
Formula | C22H21ClN4O5 |
CAS No. | 2331255-53-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL (43.8 mM), Sonication and heating to 80℃ are recommended.
You can also refer to dose conversion for different animals. More
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ABC99 2331255-53-7 Cytoskeletal Signaling Stem Cells Wnt/beta-catenin ABC 99 ABC-99 inhibitor inhibit