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Omeprazole Sodium

Catalog No. T22391 CAS 95510-70-6

Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole Sodium inhibits growth of Gram-positive and Gram-negative bacteria.

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Omeprazole Sodium, CAS 95510-70-6

Pack Size	Availability	Price/USD
100 mg	In stock	$ 41.00
200 mg	In stock	$ 58.00
500 mg	In stock	$ 97.00
1 mL * 10 mM (in DMSO)	In stock	$ 45.00

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Purity: 99.57%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole Sodium inhibits growth of Gram-positive and Gram-negative bacteria.
Targets&IC50	CYP2C19:2 to 6 μM(Ki)
In vivo	Omeprazole Sodium virtually eliminated intragastric acidity in all patients: the median 24 hour intragastric pH rose from 1.4 to 5.3 and the mean hourly hydrogen ion activity fell from 38.50 to 1.95 mmol(mEq)/1 (p less than 0.001)[1]

Molecular Weight	368.41
Formula	C17H19N3NaO3S
CAS No.	95510-70-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 120 mg/mL (326.62 mM), Sonication is recommended.

H2O: 5.5 mg/mL (14.97 mM), Sonication is recommended.

References and Literature

1. Jonkers D, et al. Omeprazole inhibits growth of gram-positive and gram-negative bacteria including Helicobacter pylori in vitro. J Antimicrob Chemother. 1996 Jan;37(1):145-50. 2. Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330. 3. Li XQ, et al. Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug Metab Dispos. 2004 Aug;32(8):821-7.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Drug Repurposing Compound Library Anti-Cancer Approved Drug Library Membrane Protein-targeted Compound Library Anti-Cancer Drug Library Anti-Cancer Clinical Compound Library Metabolism Compound Library Exosome Compound Library Approved Drug Library Bioactive Compound Library

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Keywords

Omeprazole Sodium 95510-70-6 Autophagy Membrane transporter/Ion channel Metabolism Microbiology/Virology Proton pump P450 Antibacterial Proton Pump Omeprazole H 16868 Phospholipase inhibit H-16868 Bacterial H16868 Inhibitor inhibitor

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