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Neoisoastilbin

Catalog No. TN1983   CAS 54141-72-9

Neoisoastilbin may have antioxidant and anti-inflammatory activities.

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Neoisoastilbin Chemical Structure
Neoisoastilbin, CAS 54141-72-9
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1 mg In stock $ 97.00
5 mg In stock $ 213.00
10 mg In stock $ 347.00
25 mg In stock $ 578.00
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1 mL * 10 mM (in DMSO) In stock $ 249.00
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Purity: 100%
Purity: 100%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Neoisoastilbin may have antioxidant and anti-inflammatory activities.
In vitro Phenolic-enriched extract of S. glabra (PEESG) was extracted with 70% ethanol and purified by HP-20 column chromatography. Its antioxidant and anti-inflammatory activities were evaluated by radical scavenging assay, reducing power determination, and lipopolysaccharide (LPS)-induced RAW264.7 cells assays, respectively. PEESG exhibited obviously scavenging capacity for DPPH and ABTS radicals, as well as significant reducing power for ferric ion. Particularly, PEESG (12.5-50 μg/mL) showed a significantly higher efficiency for scavenging ABTS than that of ascorbic acid and no significant difference with ascorbic acid for DPPH scavenging. PEESG also possessed a significant suppression effect on proinflammatory mediators production, such as nitric oxide (NO), tumor necrosis factor-α± (TNF-α±), and interleukin-6 (IL-6), in LPS-induced RAW264.7 cells. In addition, the main ingredients of PEESG were identified using ultrahigh pressure liquid chromatography coupled to electrospray mass spectrometry (U-HPLC-ESI-MS). Seventeen components, including 5-O-caffeoylshikimic acid, neoastilbin, astilbin, Neoisoastilbin, isoastilbin, engetin and isoengeletin were identified.
Source
Molecular Weight 450.39
Formula C21H22O11
CAS No. 54141-72-9

Storage

store at low temperture,keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/ml (122.11 mM)

TargetMolReferences and Literature

1. Antioxidant and Anti-Inflammatory Activities of Phenolic-Enriched Extracts of Smilax glabra.Evid Based Complement Alternat Med. 2014;2014:910438.

Related compound libraries

This product is contained In the following compound libraries:
Flavonoid Natural Product Library Natural Product Library for HTS

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Keywords

Neoisoastilbin 54141-72-9 Apoptosis Immunology/Inflammation NO Synthase TNF IL Receptor Inhibitor inhibit inhibitor

 

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