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Capillarisin

Catalog No. TN3587 CAS 56365-38-9

Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cells, it inhibits cancer cell growth of osteosarcoma cells by inducing apoptosis accompanied with G0/G1-phase cell cycle arrest and loss in mitochondrial membrane potential.Capillarisin has anti-inflammatory activity, can inhibit LPS-induced inflammation by blocking TLR4-mediated NF-ÎºB and MAPKs activation in BV2 microglia. Capillarisin possesses promising anti-hyperalgesic and anti-allodynic effects through the inhibition of various inflammatory pain signaling.

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Capillarisin, CAS 56365-38-9

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	316.26
Formula	C16H12O7
CAS No.	56365-38-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Capillarisin 56365-38-9 DNA损伤和修复 G蛋白偶联受体 JAK/STAT信号通路 MAPK信号通路 NF-Kb信号通路蛋白酪氨酸激酶蛋白酶体凋亡干细胞免疫与炎症神经科学细胞周期血管生成 MAPK JNK MMP IL Receptor NOS NF-κB DNA/RNA Synthesis ERK BCL COX Prostaglandin Receptor STAT VEGFR TNF TLR Inhibitor inhibitor inhibit

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