Search Result

Search Results for " α-chain "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T9553	K-transporting ATPase α chain 1 Inhibitor 1		Others
	8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-car is a H+/K+ ATPase inhibitor with IC50 of 0.38μM.		Others
TP1621	Insulin alpha-chain (1-13)	Insulin alpha-chain 1-13
	This peptide is a fragment of the alpha-chain of insulin amino acids 1 to 13. The insulin a-chain epitope recognized by human T cells is posttranslationally modified.
T13492	3,5-Diiodothyropropionic acid	C082182,Ditpa cpd	Thyroid hormone receptor(THR)
	3,5-Diiodothyropropionic acid (C082182) is a thyroid hormone analog. It induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (Ka: 2.40/M and 4.06/M for TRα1 and TRβ1).		Thyroid hormone receptor(THR)
T14834	BT2		BCL
	BT2, a BCKDC kinase (BDK) inhibitor, exhibits an IC50 of 3.19 μM and functions as a potent, selective Mcl-1 inhibitor with a Ki value of 59 μM. Its interaction with BDK induces helix movements in the N-terminal domain, l...		BCL
T22043	BCATc Inhibitor 2		Others
	BCATc Inhibitor 2 exhibited an IC50 of 0.8 microM in the hBCATc assays; it is an active and selective inhibitor. BCATc Inhibitor 2 also blocked calcium influx into neuronal cells following inhibition of glutamate uptake,...		Others
T78375	Myosin H Chain Fragment, mouse
	Myosin H Chain Fragment, mouse, is a segment of the α-Myosin heavy chain peptide and serves as an inducer of experimental autoimmune myocarditis (EAM) in mouse models [1] [2].
T80046	Myosin H Chain Fragment, mouse acetate
	Myosin H Chain Fragment, mouse acetate salt, a segment of the α-Myosin heavy chain peptide, is instrumental in developing the experimental autoimmune myocarditis (EAM) mouse model [1] [2].
T77036	Inolimomab
	Inolimomab, an anti-interleukin-2 receptor (IL-2R) α chain monoclonal antibody, has demonstrated potential to enhance survival rates in preliminary studies addressing acute graft-versus-host disease (aGVHD) [1] [2].
T82201	H-Gly-Pro-Arg-Pro-NH2
	H-Gly-Pro-Arg-Pro-NH2 is a tetrapeptide that replicates the N-terminal Gly-Pro-Arg sequence in the alpha (α) chain of fibrin and inhibits its polymerization [1].
T38189	2-hydroxy Lignoceric Acid
	2-hydroxy Lignoceric acid is an α-hydroxy very long chain fatty acid that is normally present in the mammalian nervous system. In the brain, 2-hydroxy lignoceric acid is derived from lignoceric acid and further converted...
T74023	DdGTP trisodium
	2′,3′-Dideoxyguanosine 5′-triphosphate (ddGTP) trisodium, a member of the 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs), functions as a chain-elongating inhibitor of DNA polymerase, pivotal for DNA sequencing. It...
T38008	KBC-007
	KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3...
T37458	C18 Phytoceramide (t18:0/18:0)
	C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in S. cerevisiae, wheat grains, and the stratum corneum layer of mammalian epidermis. Cer(t18:0/18:0) is composed of a phytosphingosine b...
T62826	HOIPIN-8
	HOIPIN-8 is a potent inhibitor of the linear ubiquitin chain assembly complex (LUBAC) (IC50: 11 nM). HOIPIN-8 is a derivative of HOIPIN-1 and inhibits petit-LUBAC 255-fold more than HOIPIN-1 and inhibits LUBAC and TNF-α-...
T37396	13-epi-12-oxo Phytodienoic Acid
	13-epi-12-oxo Phytodienoic acid (13-epi-12-oxo PDA) is a lipoxygenase metabolite of α-linolenic acid in the leaves of green plants such as corn. ω-3 and ω-6 polyunsaturated fatty acids in plants are substrates for plant ...

Compounds

K-transporting ATPase α chain 1 Inhibitor 1

T9553

Synonym:

Target: Others

Insulin alpha-chain (1-13)

TP1621

Synonym: Insulin alpha-chain 1-13

Target:

3,5-Diiodothyropropionic acid

T13492

Synonym: C082182,Ditpa cpd

Target: Thyroid hormone receptor(THR)

Myosin H Chain Fragment, mouse

T78375

Synonym:

Target:

Myosin H Chain Fragment, mouse acetate

H-Gly-Pro-Arg-Pro-NH2

T82201

Synonym:

Target:

2-hydroxy Lignoceric Acid

C18 Phytoceramide (t18:0/18:0)

13-epi-12-oxo Phytodienoic Acid

T37396

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
TN6768	Amylopectin		Others
	Amylopectin is a highly branched polysaccharide based on glucose. It forms starch together with amylose. The glycosidic bond of amylopectin is α- Glucan chain α- 1, 4 and branching points α- 1，6。		Others
T8144	Raffinose	Melitose,Melitriose	Others , Endogenous Metabolite
	Raffinose (Melitriose) is an indigestible short-chain oligosaccharide, a trisaccharide composed of galactose, glucose and fructose, found in many plants. It can be hydrolyzed by α-galactosidase (α-GAL) to D-galactose and...		Others , Endogenous Metabolite
TN1154	Nepetin	6-Methoxyluteolin	Calcium Channel , Histamine Receptor
	Nepetin (6-Methoxyluteolin) has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain.		Calcium Channel , Histamine Receptor
TN1163	2'-Hydroxychalcone		Others
	2'-Hydroxychalcone is a drug synthesis intermediate for the synthesis of flavonoids. 2'-Hydroxychalcone loaded in nanoemulsion showed fungicidal activity against Coccidioides parapsilosis in Danio rerio model.2'-Hydroxyc...		Others
T4839	Ac-Ala-OH	N-Acetylalanine,N-Acetyl-L-alanine	Others , Endogenous Metabolite
	Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro...		Others , Endogenous Metabolite
T4826	L-Histidine monohydrochloride monohydrat		Others , Endogenous Metabolite
	Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids, i.e., the building blocks of proteins. It is classified as a charged, polar because of the hydrophilic ...		Others , Endogenous Metabolite

Natural Products

Synonym: Melitose,Melitriose

Target: Others, Endogenous Metabolite

Nepetin

TN1154

Synonym: 6-Methoxyluteolin

Target: Calcium Channel, Histamine Receptor

Synonym: N-Acetylalanine,N-Acetyl-L-alanine

Target: Others, Endogenous Metabolite

L-Histidine monohydrochloride monohydrat

T4826

Synonym:

Target: Others, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-05539	FCGRT & B2M Heterodimer Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	FCGRT & B2M Heterodimer Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.5 kDa and the accession number is P55899&P61769.
TMPY-02082	FCGRT & B2M Heterodimer Protein, Human, Recombinant (His)	Human	HEK293 Cells
	FCGRT & B2M Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.5 kDa and the accession number is P55899-1&P61769.
TMPY-00437	IL-11R alpha chain 1/IL-11RA1 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	IL-11R alpha chain 1/IL-11RA1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.1 kDa and the accession number is A6IIX5.
TMPJ-00819	Trp A Protein, E. coli, Recombinant	E. coli	E. coli
	Trp A Protein, E. coli, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 27 KDa and the accession number is P0A877.
TMPJ-01055	HBA1 Protein, Human, Recombinant (His)	Human	E. coli
	Hemoglobin subunit alpha 1 (HBA1), also known as α2β2, is a hetero-tetramer consisting of two α and two β subunits held together by non-covalent interactions. Each subunit contains a heme group with an iron atom in the F...
TMPJ-00804	COL3A1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Collagen alpha-1(III) chain（Col3a1） is a secreted protein and belongs to the fibrillar collagen family.It contains 1 fibrillar collagen NC1 domain and 1 VWFC domain. Collagen alpha-1(III) chain is a fibrillar collagen th...
TMPY-05036	FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.3 kDa and the accession number is NP_004098.1&NP_004039.1.
TMPY-05448	FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.3 kDa and the accession number is NP_004098....
TMPJ-00921	COL8A1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Collagen alpha-1(VIII) chain, also known as endothelial collagen, C3orf7 and COL8A1, can be cleaved into vastatin chain. COL8A1 is a short chain collagen and a major component of the basement membrane of the corneal endo...
TMPJ-00948	Endostatin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Endostatin, an endogenous non‑glycosylated inhibitor of endothelial cell proliferation and angiogenesis. It is produced and/or trimmed by metalloproteinases such as MMP‑2 and MMP‑9, and cathepsins S, B and L. The N‑termi...
TMPY-00397	ITIH3 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ITIH3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 97.7 kDa and the accession number is Q06033-1.
TMPY-00198	ITIH3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ITIH3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.4 kDa and the accession number is Q06033-1.
TMPJ-00793	TPM3 Protein, Human, Recombinant	Human	E. coli
	Tropomyosin Alpha-3 Chain (TPM3) is a member of the Tropomyosin family. TPM3 exists as a heterodimer consisting of an alpha and a beta chain. TPM3 plays a central role in association with the Troponin complex and in the ...
TMPJ-00754	CRYAA Protein, Human, Recombinant (His)	Human	E. coli
	Alpha-Crystallin A Chain (CRYAA) belongs to the small heat shock protein (HSP20) family and can be induced by heat shock. The expression of CRYAA is preferentially restricted to the lens cell. CRYAA may contribute to the...
TMPY-03340	MAP1LC3A Protein, Human, Recombinant (His)	Human	E. coli
	LC3A, also known as MAP1LC3A, is one of the light chain subunits that function together with both MAP1A and/or MAP1B. MAP1A and MAP1B are microtubule-associated proteins that mediate the physical interactions between mic...
TMPJ-00755	CRYAB Protein, Human, Recombinant (His)	Human	E. coli
	α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectiv...
TMPJ-00234	AMBP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Protein AMBP belongs to the calycin superfamily and Lipocalin family. AMBP can be cleaved into three chains: α-1-microglobulin, inter-α-trypsin inhibitor light chain and trypstatin. AMBP is expressed by the liver and sec...
TMPJ-01281	COL21A1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interrupted helices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, one TSP N-terminal (TSPN) do...
TMPJ-01382	HSPB8 Protein, Human, Recombinant (His)	Human	E. coli
	Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in t...
TMPJ-00042	TSLP Protein, Human, Recombinant	Human	E. coli
	Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino aci...
TMPJ-00415	HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated	Human	HEK293 Cells
	Hepatocyte growth factor receptor (HGF R) is a glycosylated receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. HGF R is synthesized as a single chain precursor which un...
TMPK-00457	HGFR/c-Met Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain ...
TMPJ-00810	ITGA5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In cas...
TMPK-00499	HGFR/c-Met Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain ...
TMPJ-00786	ITGB1 Protein, Human, Recombinant (aa 21-728, His)	Human	HEK293 Cells
	Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue ...