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20

Compounds

Cat No. Product Name Synonyms Targets
T27837 Linzagolix GNRH Receptor
Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei Pharmaceutical and ObsEva for the treatment of uterine fibroids,...
T6713 Ulipristal Estrogen/progestogen Receptor , Progesterone Receptor
Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.
T8288 14-Deoxyandrographolide Apoptosis , Others
14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.
T2527 Ulipristal acetate Ulipristal,CDB-2914 Estrogen/progestogen Receptor , Progesterone Receptor , Autophagy
Ulipristal acetate (CDB-2914) is an orally bioavailable, acetate salt of ulipristal, a selective progesterone receptor modulator with anti-progesterone activity. Ulipristal binds to the progesterone receptor (PR), thereb...
T3630 Relugolix RVT-601,TAK-385 GNRH Receptor
Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively bi...
T22285 Carboprost 15(S)-15-Methyl Prostaglandin F2α,15-Methyl-PGF2α Prostaglandin Receptor
Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a synthetic prostaglandin analogue of PGF2α which has the effect of oxytocic. Carboprost is commonly used to restore uterine tone.
T1048 Estradiol E2,17β-Estradiol,17β-Oestradiol,β-Estradiol Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
Estradiol (E2) is a naturally occurring steroidal sex hormone that is essential for female fertility and maintenance of secondary sexual characteristics. Estradiol upregulates IL-6 expression through estrogen receptor be...
TN4422 Lauterine Topoisomerase
Lauterine is a DNA topoisomerase inhibitor.
T35054 Vilaprisan BAY 1002670,BAY10-02670,BAY-1002670,BAY1002670,BAY-10-02670,BAY 10-02670 Progesterone Receptor
Vilaprisan (BAY 1002670) is a novel orally available and selective progesterone receptor modulator (SPRM) with antiproliferative activity against uterine fibroids (UF) and can be used for the study of uterine fibroids.
TN1248 3-Epioleanolic acid AChR
3-Epioleanolic acid and oleanonic acid possess varying degrees of agonist activity on uterine smooth muscle with minor changes in the molecular structure affecting its intrinsic activity on uterine muscle.
T5148 Atosiban acetate RW22164,Atosiban acetate (90779-69-4 free base),RWJ22164 Oxytocin Receptor , Vasopressin Receptor
Atosiban acetate (RW22164) is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban acetate (RW22164) inhibits...
T1433 Ritodrine hydrochloride DU21220,Ritodrine HCl,NSC 291565 Adrenergic Receptor
Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NS...
T23516 VU590 Potassium Channel
VU590 is a potent and moderately selective inhibitor of extrarenal medullary potassium ROMK (Kir1.1).VU590 inhibits Kir7.1 and modulates uterine myometrial contractility and melanocortin signalling.
T28855 SSR126768A SSR-126768A,SSR 126768A Oxytocin Receptor
SSR126768A is a novel and selective, orally active and potent oxytocin (OT) receptor antagonist with inhibitory effects on uterine contractions for the prevention of preterm labor.
T0324 Isoxsuprine hydrochloride Duvadilan,Isolait Adrenergic Receptor , iGluR
Isoxsuprine hydrochloride (Isolait) is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle.
T14865 Carboprost tromethamine Prostaglandin Receptor
Carboprost tromethamine, a synthetic 15-methyl analogue of prostaglandin F2α, effectively promotes uterine contractions and significantly reduces bleeding during and post-delivery.
T25742 Linzagolix choline GNRH Receptor
Linzagolix choline is an orally available non-peptide gonadotropin-releasing hormone (GnRH) antagonist. It can be used to study pain associated with uterine fibroids and endometriosis.
T11915 LY88074 Estrogen/progestogen Receptor
LY88074 is a raloxifene analog in which the basic side chain has been removed. LY88074 is an agonist of ERβ (EC50 = 232 nM).This compound stimulates uterine cell proliferation.
TN1918 Medicarpin Apoptosis , BCL , ROS , JNK
Medicarpin, a legume phytoalexin, acts as an estrogen receptor (ER) agonist, can stimulate osteoblast differentiation likely via ERα², promote achievement of peak bone mass, and is devoid of uterine estrogenicity; in add...
T13572 Cancer-Targeting Compound 1 Others
Cancer-Targeting Compound 1 can be used in the study of hormone-related cancers, including the treatment or prevention of fibroids, uterine leiomyomas, polycystic ovarian syndrome, or hormone-dependent Cancer, among othe...

Compounds

Linzagolix
T27837
Synonym:
Target: GNRH Receptor
Ulipristal
T6713
Synonym:
Target: Estrogen/progestogen Receptor, Progesterone Receptor
14-Deoxyandrographolide
T8288
Synonym:
Target: Apoptosis, Others
Ulipristal acetate
T2527
Synonym: Ulipristal,CDB-2914
Target: Estrogen/progestogen Receptor, Progesterone Receptor, Autophagy
Relugolix
T3630
Synonym: RVT-601,TAK-385
Target: GNRH Receptor
Carboprost
T22285
Synonym: 15(S)-15-Methyl Prostaglandin F2α,15-Methyl-PGF2α
Target: Prostaglandin Receptor
Estradiol
T1048
Synonym: E2,17β-Estradiol,17β-Oestradiol,β-Estradiol
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite
Lauterine
TN4422
Synonym:
Target: Topoisomerase
Vilaprisan
T35054
Synonym: BAY 1002670,BAY10-02670,BAY-1002670,BAY1002670,BAY-10-02670,BAY 10-02670
Target: Progesterone Receptor
3-Epioleanolic acid
TN1248
Synonym:
Target: AChR
Atosiban acetate
T5148
Synonym: RW22164,Atosiban acetate (90779-69-4 free base),RWJ22164
Target: Oxytocin Receptor, Vasopressin Receptor
Ritodrine hydrochloride
T1433
Synonym: DU21220,Ritodrine HCl,NSC 291565
Target: Adrenergic Receptor
VU590
T23516
Synonym:
Target: Potassium Channel
SSR126768A
T28855
Synonym: SSR-126768A,SSR 126768A
Target: Oxytocin Receptor
Isoxsuprine hydrochloride
T0324
Synonym: Duvadilan,Isolait
Target: Adrenergic Receptor, iGluR
Carboprost tromethamine
T14865
Synonym:
Target: Prostaglandin Receptor
Linzagolix choline
T25742
Synonym:
Target: GNRH Receptor
LY88074
T11915
Synonym:
Target: Estrogen/progestogen Receptor
Medicarpin
TN1918
Synonym:
Target: Apoptosis, BCL, ROS, JNK
Cancer-Targeting Compound 1
T13572
Synonym:
Target: Others
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TargetMol