steatosis — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TD0093	Oil Red O		Others
	The dry dye Oil red O is used for the preparation of a staining solution that can be used for the detection of lipids in histological cryo sections.		Others
T9193	ACH-000143		Melatonin Receptor , MT Receptor
	ACH-000143 have been identified as a novel agonist of the melatonin receptors MT1 and MT2.		Melatonin Receptor , MT Receptor
T12580	PTUPB		COX , Epoxide Hydrolase
	PTUPB is a potent and dual inhibitor of sEH and COX-2 enzymes(IC50 of 0.9 nM and 1.26 μM, respectively).		COX , Epoxide Hydrolase
T7992	4-Hydroxyflavanone		NO Synthase
	4-Hydroxyflavanone is a natural product, shows full vasorelaxing effects		NO Synthase
T3888	Scopolin	Murrayin,Scopoloside	Sirtuin
	Scopolin (Scopoloside) formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for...		Sirtuin
T8732	CTPI-2		Others , Mitochondrial Metabolism
	CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 μM). CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 ha...		Others , Mitochondrial Metabolism
T0746	Orotic acid	Vitamin B13,6-Carboxyuracil	Nucleoside Antimetabolite/Analog , Dehydrogenase , Endogenous Metabolite
	Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.
T3271	Orotic acid zinc	Orotic acid zinc salt dihydrate,Zinc Orotate	Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite
	Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis.
T15779	LP-533401 hydrochloride		5-HT Receptor
	LP-533401 hydrochloride is a peripheral Tph inhibitor that cannot cross the blood-brain barrier that inhibits 5-hydroxytryptamine synthesis and can be used to study periodontal disease and hepatic steatosis.		5-HT Receptor
TN6751	1-HEXACOSANOL		NPC1L1 , AMPK
	Hexacosanol activates AMPK and hepatic autophagy and inhibits SREBP2, resulting in hypocholesterolemic activities and improvement of hepatic steatosis.		NPC1L1 , AMPK
T60004	SRI-37330		Others
	SRI-37330 inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis.		Others
T77245	Mannan		Endogenous Metabolite
	Mannan is isolated from algae, mushrooms, yeast and higher plants and acts as an immunomodulator.Mannan inhibits the pro-inflammatory activity of hepatic macrophages (M1 lineage) with protective effects against many live...		Endogenous Metabolite
T60033	SBI993		Others
	SBI993 is an analog of SBI-477 and can be used as a biomarker to confirm the expected action of MondoA target gene expression in vivo. SBI993 reduces muscle TAG levels and hepatic steatosis.		Others
T9186	Ervogastat	PF-06865571	Transferase
	Ervogastat (PF-06865571) is a potent and well-tolerated diacylglycerol acyltransferase 2 inhibitor. Ervogastat reduces steatosis and hepatic triglyceride levels in non-alcoholic steatohepatitis (NASH).		Transferase
T23097	O-1602	O1602,O 1602	Cannabinoid Receptor , Calcium Channel
	O-1602 is a novel GPR55 agonist, an atypical cannabinoid associated with the central nervous system and obesity, and is a candidate compound for the treatment of cystitis.O-1602 promotes hepatic steatosis through GPR55 a...		Cannabinoid Receptor , Calcium Channel
T5S0384	Rhapontin	Ponticin,Rhaponiticin,Rhaponticin,Rhapontigenin glucoside	Apoptosis , Others
	1. Rhapontin (Ponticin) can alleviate liver steatosis and improve blood glucose and lipid profiles in KK/Ay diabetic mice, indicates that rhaponticin has a noticeable antidiabetic effect and could be potentially used as ...		Apoptosis , Others
T6S0221	Eriocitrin	eriodictyol 7-rutinoside,Eriodictyol-7-O-Rutinoside,Eriodictioside,Eriodictyol glycoside	Apoptosis , Carbonic Anhydrase
	1. Eriocitrin (Eriodictyol-7-O-Rutinoside) is powerful antioxidative flavonoid; (1) Prevents oxidative damages caused by acute exercise-induced oxidative stress.(2) Lipid-lowering effects in a rat model of high-fat diet....		Apoptosis , Carbonic Anhydrase
T6S2391	L-Chicoric Acid	(-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid	Others , HIV Protease
	L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may ...		Others , HIV Protease
T30784	Cedrene	AI3-51328,AI3 51328,AI351328
	Cedrene can regulate hepatic steatosis via the cAMP-PKA pathway.
T68974	MHY553
	MHY 553 is a PPARα agonist that improved aged-induced hepatic steatosis.