states — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9303	MRTX1133		Ras
	MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.		Ras
T0338	Minaprine	Cantor,Minaprine dihydrochloride,Minaprina,Minaprinum	MAO , Dopamine Receptor , 5-HT Receptor , AChR , AChE , Monoamine Oxidase
	Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
T20702	Ormetoprim	Ro5-9754,Ro 5-9754,Ro-5-9754	Antibiotic
	Ormetoprim (Ro 5-9754), an antibiotic approved for use in the United States, is used to prevent the spread of disease in freshwater aquaculture.		Antibiotic
T0411	Gluconate Calcium	Calcium D-gluconate,Gluconic acid hemicalcium salt,Calcium gluconate	Others
	Gluconate Calcium (Gluconic acid hemicalcium salt) is the calcium salt of gluconic acid, used as a calcium replenisher in hypocalcemic states.		Others
T0285	Isoxicam	Isoxicamum,Isoxicamo,Maxicam	COX
	Isoxicam (Isoxicamum) is a non-steroidal anti-inflammatory drug that is not marketed in the United States.		COX
T1175	Bromopride	Bromoprida,Valopride,Artomey	Dopamine Receptor
	Bromopride (Valopride) is a dopamine antagonist with prokinetic properties closely related to metoclopramide, and is widely used as an antiemetic. It is not available in the United States or the United Kingdom.		Dopamine Receptor
T3285	Eslicarbazepine Acetate	Zebinix,Aptiom,BIA 2-093,Exalief,Stedesa	Beta-Secretase , Sodium Channel
	Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conve...		Beta-Secretase , Sodium Channel
T10674	Potassium Channel Activator 1	ZINC34634569	Potassium Channel
	Potassium Channel Activator 1 can be used in studies about the treatment of disorders or conditions wherein the dopaminergic system is disrupted such as mood disorders ADHD, schizophrenia, and other psychotic states.		Potassium Channel
T2585	Bedaquiline	R207910,TMC207	Antibacterial , Antibiotic
	Bedaquiline (R207910)(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculo...		Antibacterial , Antibiotic
T16472	Pericyazine	Propericiazine,RP 8909	Dopamine Receptor
	Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist. Pericyazine is a first-generation antipsychotic drug that is used as an adjunct to the short-term management of severe anxiety states and psych...		Dopamine Receptor
T21532	Anisodamine	6-Hydroxyhyoscyamine,6-beta-Hydroxyhyoscyamine	AChR
	Anisodamine (6-beta-Hydroxyhyoscyamine) is an antagonist of muscarinic and nicotinic cholinoceptor with similar affinities at the muscarinic receptor as scopolamine and atropine. Anisodamine improve the microcirculation ...		AChR
T0811	Amisulpride	DAN 2163	Dopamine Receptor , 5-HT Receptor
	Amisulpride (DAN 2163) (trade name Solian) is an antipsychotic drug sold by Sanofi-Aventis. It is not approved for use in the United States, but is approved for use in Europe and Australia for the treatment of psychoses ...		Dopamine Receptor , 5-HT Receptor
T1442	Pizotifen	Pizotyline,BC-105	5-HT Receptor
	Pizotifen (Pizotyline) is a strong serotonin and tryptamine antagonist, with weak anticholinergic, anti-histaminic and anti-kinin effects. It also possesses sedative and appetite-stimulating properties. Pizotifen hydroch...		5-HT Receptor
T0454	Florfenicol	Nuflor,Aquafen	Others
	Florfenicol (Aquafen) is a fluorinated synthetic analog of thiamphenicol. In the United States, florfenicol is currently used to treat bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica...		Others
T1519L	Rimonabant	SR141716	Cannabinoid Receptor , Antibacterial , Acyltransferase
	Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1. It is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. Its main avenue of effect is a reduction in appetite. Rimonabant...		Cannabinoid Receptor , Antibacterial , Acyltransferase
T0454L	Florfenicol	SCH-25298,(-)-Florfenicol	Antibacterial , Antibiotic
	Florfenicol (SCH-25298), a fluorinated synthetic analog of thiamphenicol, is currently indicated for the therapy of bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica, Haemophilus somnu...		Antibacterial , Antibiotic
T1551	Tegaserod maleate	HTF-919,SDZ-HTF-919	5-HT Receptor
	Tegaserod maleate (SDZ-HTF-919) is a 5-HT4 agonist manufactured by Novartis and used for the management of irritable bowel syndrome and constipation. Its use was the only drug approved by the United States Food and Drug ...		5-HT Receptor
T0910	Terpin hydrate	Terpin Monohydrate,cis-Terpin hydrate	Others
	Terpin hydrate, a cis-form hydrate, is derived from sources such as oil of turpentine, oregano, thyme, and eucalyptus. It is used as an insect repellent and expectorant. Terpin hydrate(cis-Terpin hydrate) is commonly use...		Others
T4S0797	Berberine	Berberin,Umbellatine	Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
	1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
T36816	S-trityl-L-Cysteine	STLC	Kinesin
	S-trityl-L-Cysteine is a non-natural amino acid and an inhibitor of Eg5, also known as KSP and Kif11, a mitotic kinesin necessary for mitotic spindle formation. S-trityl-L-Cysteine inhibits the ATPase activity of Eg5 in ...		Kinesin