sensory — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16531	Picaridin	Lcaridin	Parasite
	Picaridin (Lcaridin) is a topical insect repellent.		Parasite
T9461	AZ194		Sodium Channel
	CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.		Sodium Channel
T1030	Triprolidine hydrochloride monohydrate	Triprolidine hydrochloride	Histamine Receptor
	Triprolidine hydrochloride monohydrate is a histamine H1 antagonist used in allergic rhinitis, asthma.		Histamine Receptor
T9263	Cim0216	N-(5-methyl-1,2-oxazol-3-yl)-2-phenyl-2-(1,2,3,4-tetrahydroquinolin-1-yl)acetamide	TRP/TRPV Channel
	CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.		TRP/TRPV Channel
T8333	Aurintricarboxylic acid	ATA,NSC-4056,NSC4056,NSC 4056	Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase
	Aurintricarboxylic acid (NSC-4056) is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme.		Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase
T8776	FEMA 4774	S9632	Others
	FEMA 4774 (S9632) is a positive allosteric modulator of T1R2/T1R3. FEMA4774 shows obvious enhancement of the sweetness of sucrose in sensory evaluation tests		Others
T12632	(R)-Mirtazapine	(R)-Org3770,(R)-6-Azamianserin	5-HT Receptor
	(R)-Mirtazapine ((R)-Org3770) is the R(-)-enantiomer of Mirtazapine, which has anti-injury sensory properties in an animal model of acute thermal hyperalgesia. (R)-Mirtazapine is an antagonist of 5-HT3 receptors and a po...		5-HT Receptor
TN1308	6-Hydroxyflavanone		Others , Lipoxygenase , COX , GABA Receptor
	6-Hydroxyflavanone, extracted from the leaves of Acorus calamus, exhibits anti-inflammatory and anti-neuropathic pain activity by targeting cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), as well as opioid and GABA-A r...		Others , Lipoxygenase , COX , GABA Receptor
T21483	Tricaine methanesulfonate	MS-222	Others
	Tricaine methanesulfonate (MS-222) (TMS) is an anesthetic. Many hatcheries and research studies use TMS to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures.		Others
T1092	Zolmitriptan	311C90,BW-311C90	5-HT Receptor
	Zolmitriptan (311C90) selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries and 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and...		5-HT Receptor
T15192	Eact		Chloride channel
	Eact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in sensory nociceptors. Which also produces itch, acute nociception and thermal hypersensitivity.		Chloride channel
T5S1389	Escin IB		5-HT Receptor , NO Synthase
	Escin Ib inhibits gastric emptying, at least in part, mediated by capsaicin-sensitive sensory nerves, to stimulate the synthesis and/or release of dopamine, to act through central dopamine2 receptor, which in turn causes...		5-HT Receptor , NO Synthase
T0217L	(+)-Dropropizine	(+)-Dropropizine	Histamine Receptor
	(+)-Dropropizine can inhibit histamine receptor, anti-allergic, and reduce a cough by modulation of neuropeptides involved in the cough reflex and by interfering with stimulus activation of peripheral endings of sensory ...		Histamine Receptor
T10624	BT-13		c-RET
	BT-13 is a selective agonist of glial cell line-derived neurotrophic factor (GDNF) receptor RET independently of GFLs. BT-13 promotes neurite growth from sensory neurons in vitro.		c-RET
T29968	AMG-0347	UNII-CD7L9290QR	TRP/TRPV Channel
	AMG-0347 (UNII-CD7L9290QR) is a small molecule inhibitor targeting TRPA1(transient receptor potential ankyrin 1) ion channels, a receptor found in sensory neurons and involved in the detection of pain and environmental s...		TRP/TRPV Channel
T4513	Vanillyl butyl ether	4-(Butoxymethyl)-2-methoxyphenol,Butyl vanillyl ether	Others
	Vanillyl butyl ether (Butyl vanillyl ether) (VBE)is a capsaicin analogue,induce sensory irritation in humans,Vanillyl butyl ether is an alkoxy-substituted benzyl derivative mainly used as a flavoring agent.		Others
T23002	ML-335		Opioid Receptor
	ML-335 is a μ-δ isomer-targeted agonist, a μOR-δOR-biased ligand that can serve as a scaffold for the development of unique types of (isomer-biased) drugs.ML-335 is a MOR (μ-opioid receptor)/DOR (δ-opioid receptor) heter...		Opioid Receptor
T19317	Ethyl phenylacetate		Others
	Ethyl phenylacetate is a “greener" solvent with low toxicity. Ethyl phenylacetate is a non-mutagenic and is a Kosher food additive. Ethyl phenylacetate gives the wines a strong honey-like character. Ethyl phenylacetate i...		Others
T10572L	BMT-124110 Formate	BMT-124110 Formate（1679371-59-5 Free base）	Serine/threonin kinase , TGF-beta/Smad , AAK1 (AP2 associated kinase 1)
	BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase BIKE with an IC50: 17 nM.BMT-124110 Formate inhibits the ce...
TN1641	(-)-Fenchone		Others , Antioxidant , Antifungal
	(-)-Fenchone is a bicyclic monoterpenoid widely distributed in plants and can be extracted from Foeniculum vulgare and Peumus boldus. (-)-Fenchone has a wide range of biological activities including antioxidant, wound he...		Others , Antioxidant , Antifungal