Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Eact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in sensory nociceptors. Which also produces itch, acute nociception and thermal hypersensitivity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
2 mg | In stock | $ 44.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 128.00 | |
25 mg | In stock | $ 267.00 | |
50 mg | In stock | $ 452.00 | |
100 mg | In stock | $ 665.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 79.00 |
Description | Eact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in sensory nociceptors. Which also produces itch, acute nociception and thermal hypersensitivity. |
In vitro | Eact activates membrane currents in mTRPV1-expressing HEK293T cells in a concentration-dependent manner (EC50: 11.6 ± 2.5 μM). Eact induces both itch-and pain- related behaviours in a TRPV1-dependent manner. TMEM16A activator Eact activates both native and recombinant TRPV1 channels[1]. |
Molecular Weight | 428.5 |
Formula | C22H24N2O5S |
CAS No. | 461000-66-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (116.69 mM), Sonication is recommended.
H2O: Insoluble
You can also refer to dose conversion for different animals. More
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Eact 461000-66-8 Membrane transporter/Ion channel Chloride channel inhibit Inhibitor Chloride Channel Cl? Channels inhibitor