Shopping Cart
Remove All
Your shopping cart is currently empty
BMT-124110 Formate
Copy Product Info
😃Good
Catalog No. T10572L
Alias BMT-124110 Formate(1679371-59-5 Free base)
BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase BIKE with an IC50: 17 nM.BMT-124110 Formate inhibits the cell-cycle protein G-related BMT-124110 Formate inhibits the cell cycle protein G-associated kinase GAK with an IC50:99 nM.
BMT-124110 Formate
Copy Product Info😃Good
Purity: 98.62%
Catalog No. T10572LAlias BMT-124110 Formate(1679371-59-5 Free base)
BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase BIKE with an IC50: 17 nM.BMT-124110 Formate inhibits the cell-cycle protein G-related BMT-124110 Formate inhibits the cell cycle protein G-associated kinase GAK with an IC50:99 nM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $195 | In Stock | In Stock | |
| 5 mg | $430 | In Stock | In Stock | |
| 10 mg | $636 | In Stock | In Stock | |
| 25 mg | $987 | In Stock | In Stock | |
| 50 mg | $1,360 | In Stock | In Stock | |
| 100 mg | $1,830 | In Stock | In Stock | |
| 500 mg | $3,680 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $449 | In Stock | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:98.62%
ee:100%
Appearance:Solid
Color:White
Contact us for more batch information
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase BIKE with an IC50: 17 nM.BMT-124110 Formate inhibits the cell-cycle protein G-related BMT-124110 Formate inhibits the cell cycle protein G-associated kinase GAK with an IC50:99 nM. |
| Targets&IC50 | AAK1 (cells):3.2±1.4, BIKE:17 nM, AAK1:0.9 nM, GAK:99 nM |
| In vitro | BMT-124110 exhibits a cellular IC50 of 3.2±1.4 nM against AAK1.[1] |
| In vivo | BMT-124110 (30 mM; pH 4; 110–30 nA; 3 minutes; naive male rats) is added directly onto the spinal covered by micro iontophoresis, leading to a reduction in windup-induced activity in 10/14 animals.[1] |
| Synonyms | BMT-124110 Formate(1679371-59-5 Free base) |
| Molecular Weight | 344.41 |
| Formula | C22H20N2O2 |
| Smiles | O=C(C1=CC=CC=C1)NC2=CC=CC(C(NC3=C(CC)C=CC=C3)=O)=C2.[H]C(O)=O |
| Relative Density. | no data available |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 4.15 mg/mL (12.05 mM), Sonication is recommended.  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
| |||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
threoninkinasethreonin kinaseTGF-β/SmadTGFβTGFbeta/SmadTGF-betaTGFbetaTGF-b/SmadTGFbSmadSerinekinaseSerine kinaseGAKbone morphogenetic protein (BMP)BMT-124110 FormateBMT124110 FormateBMT 124110 FormateBIKEAP2associatedkinase1AP2 associated kinase 1AAK1(AP2associatedkinase1)AAK1 (AP2 associated kinase 1)AAK11679371-59-5 Free base1679371-59-5
Preview
Related Tags: buy BMT-124110 Formate | purchase BMT-124110 Formate | BMT-124110 Formate cost | order BMT-124110 Formate | BMT-124110 Formate chemical structure | BMT-124110 Formate in vivo | BMT-124110 Formate in vitro | BMT-124110 Formate formula | BMT-124110 Formate molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.