second — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8461	SKI V		Apoptosis , PI3K , S1P Receptor
	SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM), induces apoptosis and has antitumor activity		Apoptosis , PI3K , S1P Receptor
T0118	Mizolastine	SL 850324	Histamine Receptor
	Mizolastine (SL 850324) (IC50= 47 nM) is a histamine H1-receptor antagonist.It is used in the treatment of allergic reactions such as hay fever (seasonal allergic rhinitis), hives.		Histamine Receptor
T22285	Carboprost	15(S)-15-Methyl Prostaglandin F2α,15-Methyl-PGF2α	Prostaglandin Receptor
	Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a synthetic prostaglandin analogue of PGF2α which has the effect of oxytocic. Carboprost is commonly used to restore uterine tone.		Prostaglandin Receptor
T1118	Cefprozil monohydrate	Cefprozil,Cefprozil hydrate	Antibacterial , Antibiotic
	Cefprozil monohydrate (Cefprozil) is a second-generation cephalosporin-type antibiotic.		Antibacterial , Antibiotic
T4992	Cefamandole nafate	Cephamandole nafate,Cefamandole formate sodium	Antibacterial , Antibiotic
	Cefamandole nafate (Cephamandole nafate) is a second-generation broad-spectrum cephalosporin antibiotic.		Antibacterial , Antibiotic
T1524	Nilotinib	Tasigna,AMN107	Bcr-Abl , Autophagy
	Nilotinib (AMN107) is a second-generation Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity.		Bcr-Abl , Autophagy
T0371	Gliquidone	AR-DF 26,Glurenorm	Potassium Channel
	Gliquidone (AR-DF 26) is a potent, second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds, gliquidone exerts greater binding affinity to SUR1 and increased potency compared...		Potassium Channel
T67978	Cefuzonam
	Cefuzonam is an injectable, semi-synthetic second-generation cephalosporin with broad-spectrum antibiotic activity.
T15501	HPPH	Photochlor	Others
	HPPH (Photochlor) (Photochlor) is a second-generation photosensitizer. It is used as photodynamic therapy (PDT) agent.		Others
T1495	Cefaclor monohydrate	Cefaclor,Cefaclorum,Cefachlor	Antibacterial , Antibiotic
	Cefaclor monohydrate (Cefaclorum) is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.		Antibacterial , Antibiotic
T4950	1,2-Dipalmitoyl-sn-glycerol	(S)-1,2-Dipalmitin	Endogenous Metabolite , PKC
	1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.		Endogenous Metabolite , PKC
T6801	CeMMEC13		Carboxypeptidase , DNA/RNA Synthesis
	CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).		Carboxypeptidase , DNA/RNA Synthesis
T6S0214	Dl-Maackiain	(+)-Maackiain,Demethylpterocarpin	Apoptosis , Parasite
	1. dl-Maackiain (Demethylpterocarpin) induces apoptosis and growth suppression 2. MAK1 is the second functional gene cloned from Maackiain detoxification.		Apoptosis , Parasite
T4523	TP-3654		Pim
	TP-3654 is a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).		Pim
T1227	Cefuroxime axetil	Cepazine,Zinnat,Elobact,Ceftin	Antibacterial , Antibiotic
	Cefuroxime axetil (Zinnat) is a second generation oral cephalosporin antibiotic.		Antibacterial , Antibiotic
T5833	CC-401 Hydrochloride	CC401 HCl	JNK
	CC-401 Hydrochloride (CC401 HCl) is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor (Ki of 25 to 50 nM.)with potential antineoplastic activity.		JNK
T1330	Acitretin	Ro 10-1670,Etretin	Apoptosis , Retinoid Receptor , Autophagy
	Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.		Apoptosis , Retinoid Receptor , Autophagy
T1470	Fexofenadine hydrochloride	Terfenidine carboxylate hydrochloride,MDL-16455 hydrochloride,Telfast,Fexofenadine HCl,Allegra,MDL 16455A	Histamine Receptor
	Fexofenadine hydrochloride (Terfenidine carboxylate hydrochloride) is a second generation antihistamine that is used for the treatment of allergic rhinitis, angioedema and chronic urticaria.		Histamine Receptor
T2147	Nilotinib monohydrochloride monohydrate	Nilotinib (monohydrochloride monohydrate),AMN107 (monohydrochloride monohydrate)	Bcr-Abl , Autophagy
	Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosine kinase inhibitor (TKI), and is active against many BCR-ABL muta...		Bcr-Abl , Autophagy
TQ0053	Fadraciclib	CYC065	CDK
	Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).		CDK