20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T79981 | Nitric oxide production-IN-1 | NO Synthase | |
Nitric oxide production-IN-1 (Compound 1) is an inhibitor of nitric oxide (NO) production extracted from Tupistra chinensis. It effectively suppresses NO synthesis in rat abdominal macrophages upon stimulation with lipop... | |||
TP2195 | Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell | Others | |
Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell (Ac-Pro-Tyr-Asn-Ser-Ser-Pro-Arg-Pro-Glu-Gln-His-Lys-Ser-Tyr-Lys-Cys) is a peptide that inhibits the function of NOSs as a result it blocks the pro... | |||
TQ0301 | Kuwanon A | NO Synthase | |
Kuwanon A inhibits nitric oxide production (IC50: 10.5 μM). Kuwanon A is a flavone derivative isolated from Morus alba L. | |||
T6S2023 | Harpagoside | Others , COX , NO Synthase | |
1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression... | |||
T2S0765 | Epibetulinic acid | NO Synthase , Prostaglandin Receptor | |
Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin. | |||
T6S1665 | Irisflorentin | Others , NO Synthase | |
1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechan... | |||
T7682 | Asymmetric dimethylarginine | Endogenous Metabolite , NO Synthase , NOD | |
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS) | |||
T7474 | 7-Nitroindazole | NOS | |
7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS. | |||
T10107 | 3-Bromo-7-nitroindazole | NOS | |
3-Bromo-7-nitroindazole is a more potent and selective inhibitor of neuronal nitric oxide synthase (nNOS) than eNOS or iNOS. It affects the intercellular messenger NO synthesis throughout the brain and body. | |||
TN1058 | Pelargonidin chloride | NOS , Reactive Oxygen Species , Nrf2 , NO Synthase | |
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway. | |||
T3847 | Asperuloside | Asperulosid | Others , NO Synthase |
Asperuloside (Asperulosid) has anti-inflammatory activity. | |||
T1322 | Bendazol | Dibazol,Dibazole | Dopamine Receptor , NO Synthase |
Bendazol (Dibazol) is always used as the drug for hypertension and cerebral Angiospasm. | |||
T5838 | L-Canavanine sulfate | NO Synthase , NOD | |
L-Canavanine sulfate is a selective inducible NO synthase inhibitor. | |||
T5S0285 | Cistanoside A | Others | |
1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respirat... | |||
T22724 | Dimaprit dihydrochloride | NOS , NO Synthase , Histamine Receptor | |
Dimaprit dihydrochloride is a selective histamine H2 receptor agonist. Dimaprit dihydrochloride also inhibits nNOS with an IC50 of 49 μM. It can stimulate gastric acid secretion. | |||
T2791 | Pectolinarin | Apoptosis , Others , NO Synthase , Prostaglandin Receptor , Interleukin | |
Pectolinarin is a Cirsium isolate with anti-inflammatory activity. | |||
T4808 | Agmatine sulfate | Agmatine sulfate salt | Endogenous Metabolite , NO Synthase , Imidazoline Receptor |
Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide sy... | |||
T7597 | 6-Biopterin | L-Biopterin | Endogenous Metabolite , NO Synthase , NOD |
6-Biopterin (L-Biopterin) is a natural product,is a NO synthase cofactor. | |||
T21712 | BAY 41-8543 | Others , Guanylate cyclase | |
BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC). | |||
TN2139 | Regaloside B | NOS , COX , NO Synthase | |
Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric oxide synthase) and COX-2 (cyclooxygenase-2). |