neonatal — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T21793	CGP 35348		GABA Receptor
	CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice.		GABA Receptor
T7714	Temocapil		Tyrosinase
	Temocapril is an inhibitor of tyrosine kinase.		Tyrosinase
T23283	2-Methoxyidazoxan monohydrochloride	RX 821002 hydrochloride	Adrenergic Receptor
	L-Albizziin (2-Methoxyidazoxan monohydrochloride) is a highly potent selective antagonist of the alpha 2r adrenergic receptor, with little or no antagonistic effect on imidazoline. It has a significantly higher affinity ...		Adrenergic Receptor
T6698	Temocapril hydrochloride	CS-622 HCl,Acecol,Temocapril HCl,CS-622	RAAS
	Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.		RAAS
T29670	ADR-925	ICRF198,ICRF-198,ADR 925,ICRF 198,ADR925	Endogenous Metabolite
	ADR-925 (ICRF 198), an active chelated iron metabolite of dexrazoxane, has the ability to protect neonatal rat cardiomyocytes from adriamycin-induced injury.		Endogenous Metabolite
T11339L	Furegrelate		PPAR
	FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.		PPAR
T28607	Rocepafant	LAU 8080,LAU8080,BN 50730,LAU-8080,BN50730,BN-50730	Platelet aggregation
	Rocepafant (LAU8080) is a platelet-activating factor (PAF) antagonist that attenuates hypoxic-ischemic brain damage in neonatal rats.Rocepafant inhibits tumor necrosis factor-Afa-mediated cytotoxicity in mouse L929 tumor...		Platelet aggregation
T5252	Tridecanedioic acid	1,11-Undecanedicarboxylic acid,1,13-Tridecanedioic acid,Brassilic acid	Others , Endogenous Metabolite
	Tridecanedioic acid (Brassilic acid) is an unusual odd-numbered dicarboxylic acid that appears in the urines of children with neonatal adrenoleukodystrophy and Zellweger syndrome, as an additional marker of these peroxis...		Others , Endogenous Metabolite
T23215L	(R)-3,4-DCPG HCl	(R)-3,4-DCPG HCl(201730-10-1 Free base)	GluR
	(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord.		GluR
T7578	REVERSE T3	3,3',5'-triiodo-L-thyronine	Thyroid hormone receptor(THR)
	Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.		Thyroid hormone receptor(THR)
T4762	L-Pipecolic acid	L-Homoproline,H-HoPro-OH	Endogenous Metabolite
	L-Pipecolic acid (L-Homoproline) is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as Zellweger syndrome, neonatal adrenoleukodystrophy.		Endogenous Metabolite
T7284	Argipressin acetate (113-79-1(free base))		Others
	Vasopressin acetate is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle...		Others
T68123	Oxodipine		Calcium Channel
	Oxodipine, a dihydropyridine-type calcium antagonist , inhibited KCl-induced aortic contraction in rabbits and reduced cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventri...		Calcium Channel
T0005	Aspirin	Acetylsalicylate,Acetylsalicylic Acid,ASA	Mitophagy , Virus Protease , COX , Autophagy
	Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel...		Mitophagy , Virus Protease , COX , Autophagy
T82545	Disialyllacto-N-tetraose
	Disialyllacto-N-tetraose, a human milk oligosaccharide, has been shown to prevent necrotizing enterocolitis in neonatal rats [1].
TN6453	Nardoaristolone B
	Nardoaristolone B, a nor-sesquiterpenoid with an unusual fused ring system and having protective effects on the injury of neonatal rat cardiomyocytes. The novel mosquito-repellentsynthetic hydrindanesbased on noreremophi...
T63715	HIgG–hFc receptor-IN-1
	hIgG-hFc receptor-IN-1 is a human immunoglobulin G - human neonatal Fc receptor (hIgG-hFcRn) protein-protein interaction inhibitor (IC50: 2 μM).
T72734	3-Fucosyllactose	3-Fucosyl-D-lactose
	3-Fucosyllactose (3-Fucosyl-D-lactose), a predominant fucosylated oligosaccharide in human breast milk, exhibits prebiotic, immunomodulating, neonatal brain development, and antimicrobial functions.
TP2012	JMV 449
	Potent, metabolically stable neurotensin receptor agonist peptide (IC50 = 0.15 nM for inhibition of [125I]-NT binding to neonatal mouse brain; EC50 = 1.9 nM for contraction of guinea pig ileum). Produces long-lasting hyp...
TP1171	Apraglutide TFA (1295353-98-8 free base)	Apraglutide TFA,FE 203799e (TFA)
	Apraglutide TFA (FE 203799 TFA), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resectio...