gated — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22408	Proflavine	3,6-Diaminoacridine	Antibacterial
	Proflavine (3,6-Diaminoacridine) (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria and is a topical antiseptic used mainly in wound dressings.		Antibacterial
T19723	AMTB hydrochloride	AMTB	TRP/TRPV Channel
	AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive refl...		TRP/TRPV Channel
T15260	Evenamide	NW-3509	Sodium Channel
	Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.		Sodium Channel
T0939	Phenytoin	Diphenylhydantoin,5,5-Diphenylhydantoin	Virus Protease , Sodium Channel
	Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux from neurons located in the motor cor...		Virus Protease , Sodium Channel
T0438	Proflavine Hemisulfate	3,6-Diaminoacridine hemisulfate,Proflavin hemisulfate	Others , Potassium Channel , DNA , Thrombin , Antibacterial , Autophagy
	Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant agent that can potentially be used for cellular imaging and a...
T4497	Amifampridine	3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine	Others
	Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is ...		Others
T2535	Ivabradine hydrochloride	S 16257-2,Ivabradine HCl	Adrenergic Receptor
	Ivabradine hydrochloride (S 16257-2) is a new If inhibitor (IC50: 2.9 μM). Ivabradine Hydrochloride is the hydrochloride salt form of ivabradine, an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gat...		Adrenergic Receptor
T7806	Licarbazepine	10,11-hydroxy-10,11 Dihydrocarbamezer	Others
	Licarbazepine (10,11-hydroxy-10,11 Dihydrocarbamezer) is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders.		Others
T0008	Phenytoin sodium	5,5-Diphenylhydantoin sodium salt,Diphantoine,Dilantin sodium,Diphenylhydantoin Sodium	Virus Protease , Sodium Channel
	Phenytoin sodium (Diphantoine) is an inactive stabilizer for voltage-gated sodium channel .		Virus Protease , Sodium Channel
T8333	Aurintricarboxylic acid	ATA,NSC-4056,NSC4056,NSC 4056	Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase
	Aurintricarboxylic acid (NSC-4056) is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme.		Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase
T7516	ZD7288	ICI D7288	HCN Channel
	ZD7288 (ICI D7288), a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity.		HCN Channel
T2173	Veratridine		Sodium Channel
	Veratridine is a benzoate-cevane found in Veratrum and Schoenocaulon. It activates sodium channels to stay open longer than normal.		Sodium Channel
T11990	Meclofenamic acid	Meclofenamate	Others , Gap Junction Protein
	Meclofenamic acid (Meclofenamate) is a non-selective gap-junction blocker and a selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic acid has anti-inflammatory activities.		Others , Gap Junction Protein
T19988	Conjugated Estrogen sodium	Conjugated estrogens,Conest,HSDB 3076,Kestrin,Estrogens, conjugated,TAG-39
	Conjugated estrogens are medicine that contains a mixture of estrogen hormones. It is used to treat moderate to severe hot flashes, changes in and around the vagina, and other symptoms of menopause or low amounts of estr...
T21009	Conjugated linoleic acid
	Conjugated linoleic acid, a naturally occurring fatty acid, is present in ruminant meat and dairy products and is produced by a bio-hydrogenation process in the rumen. In this case, the predominant isomer formed is 9cis,...
T37270	9(E),11(E)-12-nitro Conjugated Linoleic Acid
	9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combinat...
T80249	Epsilon-V1-2, Cys-conjugated		PKC
	Epsilon-V1-2, a Cys-conjugated, is a biologically active peptide known as the εPKC-specific inhibitor. It hampers εPKC functionality by obstructing its translocation and the phosphorylation of MARCKS, additionally pertur...		PKC
T74877	GalNAc unconjugated/naked Fitusiran
	GalNAc unconjugated/naked Fitusiran, an small interfering RNA without GalNAc conjugation, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. GalNAc unconjugated/naked Fitusiran i...
T74876	GalNAc unconjugated/naked Inclisiran
	Inclisiran (unconjugated/naked) is a double-stranded small interfering RNA (siRNA) that lacks GalNAc conjugation. This compound selectively inhibits the transcription of PCSK-9, making it applicable in the research of hy...
T35854	9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
	9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor α (PPARα; IC50= 140 nM) and activates the receptor in a r...