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9(E),11(E)-12-nitro Conjugated Linoleic Acid

Catalog No. T37270 CAS 1515620-30-0

9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .29(E),11(E)-12-nitro CLA has been found in human plasma.

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9(E),11(E)-12-nitro Conjugated Linoleic Acid Chemical Structure

9(E),11(E)-12-nitro Conjugated Linoleic Acid, CAS 1515620-30-0

Pack Size	Availability	Price/USD
50 μg	35 days	$ 93.00
100 μg	35 days	$ 170.00
250 μg	35 days	$ 394.00
500 μg	35 days	$ 753.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	325.449
Formula	C18H31NO4
CAS No.	1515620-30-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 50 mg/mL

DMF: 50 mg/mL

DMSO: 50 mg/mL

0.1 M Na2CO3: 1 mg/mL

References and Literature

1. Woodcock, S.R., Salvatore, S.R., Bonacci, G., et al.Biomimetic nitration of conjugated linoleic acid: Formation and characterization of naturally occurring conjugated nitrodienesJ. Org. Chem.79(1)25-33(2014) 2. Bonacci, G., Baker, P.R.S., Salvatore, S.R., et al.Conjugated linoleic acid is a preferential substrate for fatty acid nitrationJ. Biol. Chem.287(53)44071-44082(2012)

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Keywords

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