gastroesophageal — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T20626	Esomeprazole		Proton pump , Cysteine Protease
	Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibitors (PPI).		Proton pump , Cysteine Protease
T0081	Lafutidine	FRG-8813	5-HT Receptor , Histamine Receptor
	Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion.		5-HT Receptor , Histamine Receptor
T1575	Nizatidine	Axid,Acinon,Zanizal	AChE , Histamine Receptor
	Nizatidine (Acinon) is a competitive and reversible histamine H2-receptor antagonist with antacid activity.		AChE , Histamine Receptor
T2686L	Esomeprazole Sodium	(S)-Omeprazole sodium	ATPase , Proton pump
	Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an exosome inhibitor by blocking the exosome release via the i...		ATPase , Proton pump
T8388	Vonoprazan	TAK-438 (free base)	Proton pump
	Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis		Proton pump
T21254	Vonoprazan Fumarate	TAK-438,TAK 438,Vonoprazan Fumurate,TAK438	Proton pump
	Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19...		Proton pump
T1651	Rabeprazole sodium	Dexrabeprazole Sodium,LY307640 sodium,Habeprazole Sodium,Rebeprazole sodium,Aciphex Sodium	Apoptosis , Proton pump
	Rabeprazole sodium (Habeprazole Sodium) is a 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of stomach ulcers and Zollinger-Ellison syndrome. The drug inhibits H(+)-K(+)-exch...		Apoptosis , Proton pump
T14389	AZD 9272		GluR
	AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.		GluR
T2093	PF 03716556	PF-3716556	ATPase
	PF 03716556 (PF-3716556) , an effective and specific P-CAB (potassium-competitive acid blocker), is utilized for the treatment of gastroesophageal reflux disease.		ATPase
T21651	Lansoprazole sodium	Lansoprazole (sodium), AG-1749 sodium	Proton pump , Phospholipase , Antibacterial
	Lansoprazole sodium (Lansoprazole (sodium)) is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity which is widely used in the therapy of gastroesophageal reflux and peptic ulcer disease.		Proton pump , Phospholipase , Antibacterial
T0161	Pantoprazole Sodium Hydrate	SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate)	Apoptosis , Potassium Channel , Proton pump , Autophagy
	Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Potassium Channel , Proton pump , Autophagy
T69984	Ticalopride		5-HT Receptor
	Ticalopride is a 5-HT3 receptor agonist used in the treatment of digestive disorders, orofacial disorders, otorhinolaryngologic disorders, and may be used in the study of bulimia nervosa, gastroesophageal reflux, and irr...		5-HT Receptor
T6928	Pantoprazole	SKF96022,BY1023	Apoptosis , Proton pump , Autophagy
	Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Proton pump , Autophagy
T1756L	Ilaprazole	IY81149,IY 81149,IY-81149	Proton pump , TOPK
	Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the developm...		Proton pump , TOPK
T8386	Esomeprazole Magnesium trihydrate	(S)-Omeprazole magnesium trihydrate	Proton pump
	Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagit...		Proton pump
T10221	Abeprazan hydrochloride	DWP14012 hydrochloride,Fexuprazan hydrochloride	Proton pump
	Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to potassium ions without acid activat...		Proton pump
T4616	Metoclopramide	5-Chloro-2-methoxyprocainamide	Dopamine Receptor , 5-HT Receptor
	Metoclopramide (5-Chloro-2-methoxyprocainamide) is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is ...		Dopamine Receptor , 5-HT Receptor
T33402	Mitemcinal fumarate	GM 611,Kita-ku Tokyo,GM-611,Kita-ku Toyko,GM611
	Mitemcinal fumarate is a erythromycin derivative that is used to treat gastroesophageal reflux disease.
T26727	Azeloprazole	E-3710,Z215,E3710,Z 215,E 3710,Z-215
	Azeloprazole, a proton pump inhibitor, is used potentially for the treatment of gastroesophageal reflux disease (GERD).
T27640	Itriglumide	CR-2945,CR2945,CR 2945
	Itriglumide, a CCK2 receptor antagonist, is used potentially for the treatment of peptic ulcers, dyspepsia, and gastroesophageal reflux disease (GERD).