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Search Results for " depression "

20

Compounds

Cat No. Product Name Synonyms Targets
TN1120 Osthenol MAO , Monoamine Oxidase
Osthenol is a natural product, and is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM).It shows antitumor-promoting activity, it also has antifungal and antibacterial activ...
T10232 Acetophenazine dimaleate Dopamine Receptor
Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression. Acetophenazine dimaleate primarily targets the dopamine D2 receptor.
T9787 Suvn-911 AChR
suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.
TQ0289 LY450108 iGluR
LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.
T1997 JNJ-31020028 JNJ 31020028 Neuropeptide Y Receptor
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2 versus human Y1/Y4/Y5 receptors.
T23070 Nisoxetine hydrochloride Sodium Channel , Monoamine Transporter , Norepinephrine
Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor
TN6490 Regaloside C Others
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties.
T23513 VU10010 VU 10010 AChR
VU10010 (VU 10010) is allosteric potentiator of M4 acetylcholine receptors.
T6043 PF-3845 FAAH , Autophagy
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.
T9272 Xaliproden hydrochloride Dopamine Receptor , 5-HT Receptor
Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist.
T15260 Evenamide NW-3509 Sodium Channel
Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.
T3885 ROSIRIDIN 6'-O-Deacetylrosiridoside C,(-)-Rosiridin Others , Monoamine Oxidase
Rosiridin (6'-O-Deacetylrosiridoside C) has cardioprotective activity.
T21011 Buspirone Buspirone free base,Ansial 5-HT Receptor
Buspirone (Buspirone free base) is an azaspiro compound which has a role as an anxiolytic drug, a sedative, a serotonergic agonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor.
TN2004 Obtusin MAO , Monoamine Oxidase
Obtusin is a natural product.
T2371 Emapunil AC-5216,XBD-173 Others
Emapunil (XBD-173) is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO.
T21654 1-Oleoyl lysophosphatidic acid sodium 1-Oleoyl lysophosphatidic acid sodium salt LPA Receptor
1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2
T2132 Buspirone hydrochloride Buspirone HCl,Narol,Buspar Dopamine Receptor , 5-HT Receptor
Buspirone hydrochloride (Buspar) is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD).
T0185 Escitalopram Seroplex,S-(+)-Citalopram,(S)-Citalopram Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patien...
T6975 Sarcosine Sarcosinic acid,Methylaminoacetic acid,Sarcosin,Methylglycine,N-Methylaminoacetic acid,N-methylglycine Others , GlyT , Endogenous Metabolite
Sarcosine (Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist.
T0293 Metyrapone NSC-25265,Su-4885 Others , P450 , Dehydrogenase , Autophagy
Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.

Compounds

Osthenol
TN1120
Synonym:
Target: MAO, Monoamine Oxidase
Acetophenazine dimaleate
T10232
Synonym:
Target: Dopamine Receptor
suvn-911
T9787
Synonym:
Target: AChR
LY450108
TQ0289
Synonym:
Target: iGluR
JNJ-31020028
T1997
Synonym: JNJ 31020028
Target: Neuropeptide Y Receptor
Nisoxetine hydrochloride
T23070
Synonym:
Target: Sodium Channel, Monoamine Transporter, Norepinephrine
Regaloside C
TN6490
Synonym:
Target: Others
VU10010
T23513
Synonym: VU 10010
Target: AChR
PF-3845
T6043
Synonym:
Target: FAAH, Autophagy
Xaliproden hydrochloride
T9272
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
Evenamide
T15260
Synonym: NW-3509
Target: Sodium Channel
ROSIRIDIN
T3885
Synonym: 6'-O-Deacetylrosiridoside C,(-)-Rosiridin
Target: Others, Monoamine Oxidase
Buspirone
T21011
Synonym: Buspirone free base,Ansial
Target: 5-HT Receptor
Obtusin
TN2004
Synonym:
Target: MAO, Monoamine Oxidase
Emapunil
T2371
Synonym: AC-5216,XBD-173
Target: Others
1-Oleoyl lysophosphatidic acid sodium
T21654
Synonym: 1-Oleoyl lysophosphatidic acid sodium salt
Target: LPA Receptor
Buspirone hydrochloride
T2132
Synonym: Buspirone HCl,Narol,Buspar
Target: Dopamine Receptor, 5-HT Receptor
Escitalopram
T0185
Synonym: Seroplex,S-(+)-Citalopram,(S)-Citalopram
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor
Sarcosine
T6975
Synonym: Sarcosinic acid,Methylaminoacetic acid,Sarcosin,Methylglycine,N-Methylaminoacetic acid,N-methylglycine
Target: Others, GlyT, Endogenous Metabolite
Metyrapone
T0293
Synonym: NSC-25265,Su-4885
Target: Others, P450, Dehydrogenase, Autophagy
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TargetMol