cirrhosis — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19399	L-Ornithine L-aspartate	Ornithine Aspartate	Others
	L-Ornithine L-aspartate (Ornithine Aspartate) lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis.		Others
T8117	Metenolone acetate	Methenolone acetate	Others , Androgen Receptor
	Metenolone acetate (Methenolone acetate) is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure.		Others , Androgen Receptor
T1410	Torsemide	AC-4464,JDL-464,Torasemide	Na-K-Cl cotransporter
	Torsemide (AC-4464) is an anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and h...		Na-K-Cl cotransporter
T3611	Sodium Glucuronic Acid	Sodium Glucoronic,4-FLUOROCINNAMONITRILE	Others
	Sodium Glucuronic Acid (4-FLUOROCINNAMONITRILE) is used in the treatment of hepatitis and liver cirrhosis.		Others
T6576	Malotilate	Malotilatum,NKK 105,Kantec	Lipoxygenase
	Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.		Lipoxygenase
T60226	CT52923		PDGFR
	CT52923 is a selective, orally active antagonist of platelet-derived growth factor receptor (PDGFR), functioning as an ATP-competitive inhibitor. It has versatile applications for researching an array of pathological dis...		PDGFR
T6993	Tauroursodeoxycholate sodium	Sodium tauroursodeoxycholate,Tauroursodeoxycholic acid sodium salt,TUDC,Sodium Tauroursodeoxycholate (TUDC)	Apoptosis , ERK , Caspase
	Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.		Apoptosis , ERK , Caspase
T63751	Selvigaltin	GB1211	Neuropeptide Y Receptor
	Selvigaltin (GB1211) is a Gal-3 inhibitor with potential anticancer activity. Selvigaltin is used in the study of cirrhosis and cancer.		Neuropeptide Y Receptor
T5233	N-Methylnicotinamide	N'-Methylnicotinamide,Nicotinic Acid Methylamide,N-Methylpyridine-3-carboxamide	Others , Endogenous Metabolite
	N-Methylnicotinamide (Nicotinic Acid Methylamide) is a metabolite of niacin (or nicotinamide) and is commonly found in human urine. However low levels of urinary excretion of N-Methylnicotinamide (Nicotinic Acid Methylam...		Others , Endogenous Metabolite
T73446	BI‑3231		Dehydrogenase
	BI‑3231 is a selective and potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis...		Dehydrogenase
T62882	Ezurpimtrostat hydrochloride
	Ezurpimtrostat hydrochloride (compound 2-3) is an orally active antifibrotic agent that significantly reduces liver fibrosis in rats with DEN (diethylnitrosamine) cirrhosis. CTSB, CTSL and CTSD related diseases.
T76700	Simtuzumab	GS 6624,AB 0024	Monoamine Oxidase
	Simtuzumab is a monoclonal antibody against lysyl oxidase-like protein 2 (LOXL2). Simtuzumab can be used to treat primary sclerosing cholangitis (PSC) and is not effective in patients with bridging fibrosis or compensato...		Monoamine Oxidase
T2532	Tauroursodeoxycholate	Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA	Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
	Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. Tauroursodeoxycholate is the more hydrophilic form of ursode...		Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
T3753	Sinapinic Acid	Sinapic acid,Synapoic acid	Apoptosis , RAAS , Reactive Oxygen Species , HDAC
	Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinap...		Apoptosis , RAAS , Reactive Oxygen Species , HDAC
T28664	Satavaptan	SR121463,SR 121463,SR-121463
	Satavaptan is a vasopressin V2 receptor antagonist. Satavaptan improves the control of ascites in cirrhosis.
T34107	Polythiazide	P2525,NSC-108161,NSC 108161,P-2525,NSC108161
	Polythiazide (NSC-108161, P-2525) is used to treat fluid retention (edema) caused by a variety of causes, including congestive heart failure, severe liver disease (cirrhosis), kidney disease, or steroid or hormonal medic...
T34773	TAK-044	TAK044
	TAK-044 is an endotheliin receptor antagonist that prevents and reverses the development of carbon tetrachloride induced cirrhosis in rats. TAK-044 showed a protective effect on neuronal activity in vitro hypoxic glucose...
T80270	Invopressin	OCE-205	Vasopressin Receptor
	Invopressin (Compound 42), a vasopressin V1A receptor partial agonist (EC50: 1.0 nM), is utilized in research related to cirrhosis conditions such as bacterial peritonitis, HRS2, and refractory ascites [1].		Vasopressin Receptor
T69133	Etozolin HCl
	Etozolin HCl is a safe and effective diuretic agent in the treatment of acute cardiac failure. In isolated rings of guinea-pig aorta not responding to acetylcholine, the diuretic dexetozoline did not influence basal vasc...
T37177	Norcholic Acid
	Norcholic acid is a bile acid and 23-carbon derivative of cholic acid .1Levels of norcholic acid are increased in the urine of patients with liver cirrhosis or cerebrotendinous xanthomatosis (CTX), an inborn error of met...