carboxamide — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1705	5-Amino-3H-imidazole-4-Carboxamide	4-Amino-5-imidazolecarboxamide,AICA,5-Aminoimidazole-4-carboxamide	Endogenous Metabolite
	5-Amino-3H-imidazole-4-Carboxamide (AICA) is an imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparat...		Endogenous Metabolite
T37009	Oxychlororaphine	phenazine-1-carboxamide	Antibacterial
	Oxychlororaphine (phenazine-1-carboxamide) inhibits strongly the growth of Streptomyces sp. 441.		Antibacterial
T50032	5-(2-furyl)-N-propylisoxazole-3-carboxamide		Others
	5-(2-furyl)-N-propylisoxazole-3-carboxamide is a compound used as a molecular structural unit and is thought to be a modulator of NMDA receptors, and has been shown to be protective against glutamate-induced excitotoxici...		Others
T1120	Dacarbazine	Imidazole Carboxamide,DTIC-Dome	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas.
T8502	N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide		Influenza Virus
	N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide inhibiting the entry of Ebola virus in host cells by binding to the surface glycoprotein, the compound inhibited the Ebola virus with EC50 of 3.9 μM.		Influenza Virus
T25175	BRD 9757	BRD9757,N-Hydroxy-1-cyclopentene-1-carboxamide,BRD-9757	HDAC
	BRD 9757 (N-Hydroxy-1-cyclopentene-1-carboxamide) is a selective inhibitor of HDAC6 (IC50 = 30 nM).		HDAC
T22009	CB2 receptor agonist 2	ZINC72105556,4-Quinolone-3-Carboxamide Furan CB2 Agonist	Cannabinoid Receptor
	CB2 receptor agonist 2 (ZINC72105556) is a potent and selective agonist for the CB2 (cannabinoid type 2) receptor, Ki = 8.5 nM. CB2 receptor agonist 2 has high affinity and selectivity for CB2.		Cannabinoid Receptor
T8501	3-Phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-tricyclo[3.3.1.13,7]decane-1-carboxamide		Influenza Virus
	3- Phenyl- N- [1- (phenylmethyl) - 4- piperidinyl] -tricyclo[3.3.1.13, 7] decane- 1- carboxamide with antiviral activity against Ebola virus that targets the surface-exposed glycoprotein and inhibits viral entry into hos...		Influenza Virus
T19214	Bredinin aglycone	5-Hydroxy-1H-imidazole-4-carboxamide,SM-108	Others
	Bredinin aglycone (SM-108) is a purine nucleotide analog. It can be used to examine the efficiency of catalysts for the preparation of purine nucleotide analogs.		Others
T22988	MK-4827 Racemate	Niraparib Racemate,2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide	PARP
	MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.		PARP
T9679	N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyrazine-2-carboxamide		Antibacterial
	N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyrazine-2-carboxamide exhibit an inhibitory effect on bacterial DNA helicases, nucleases, or helicase-nuclease enzyme complexes, such as, for example, one or more enzym...		Antibacterial
T5233	N-Methylnicotinamide	N'-Methylnicotinamide,Nicotinic Acid Methylamide,N-Methylpyridine-3-carboxamide	Others , Endogenous Metabolite
	N-Methylnicotinamide (Nicotinic Acid Methylamide) is a metabolite of niacin (or nicotinamide) and is commonly found in human urine. However low levels of urinary excretion of N-Methylnicotinamide (Nicotinic Acid Methylam...		Others , Endogenous Metabolite
TN7142	N-methyl-1H-indole-2-carboxamide	1H-indole-2-carboxylic acid methylamide,ZINC35137534	Others
	N-methyl-1H-indole-2-carboxamide (ZINC35137534) is a marine derived natural products found in Neosartorya pseudofischeri.		Others
T6833	Favipiravir	T-705,6-Fluoro-3-oxo-3,4-dihydropyrazine-2-carboxamide	Others , SARS-CoV , Influenza Virus , DNA/RNA Synthesis
	Favipiravir (T-705) (T-705), an effective and selective RNA-dependent RNA polymerase inhibitor, are applied to treat influenza virus infections.		Others , SARS-CoV , Influenza Virus , DNA/RNA Synthesis
T8150	Nudifloramide	1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide	PARP , Endogenous Metabolite
	Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).		PARP , Endogenous Metabolite
T60041	N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide		Microtubule Associated
	N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM.		Microtubule Associated
T60087	CFMS Receptor Inhibitor IV	5-cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide	c-Fms
	cFMS Receptor Inhibitor IV is an inhibitor of c-Fms tyrosine kinase.		c-Fms
T16109	ML402	ZINC3671497,N-[2-(4-chloro-2-methylphenoxy)ethyl]thiophene-2-carboxamide	Potassium Channel
	ML402 (ZINC3671497) is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.		Potassium Channel
T16950	Sudoxicam	4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide	COX
	Sudoxicam (4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) is a reversible antagonist of COX with anti-inflammatory, anti-edema, and antipyretic properties.		COX
T5962	TRPM8 antagonist WS-3	Cyclohexanecarboxamide,N-Ethyl-p-menthane-3-carboxamide,N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide	TRP/TRPV Channel
	TRPM8 antagonist WS-3 (Cyclohexanecarboxamide) is an agonist of TRPM8( EC50 : 3.7 μM).		TRP/TRPV Channel