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Cat No. | Product Name | Synonyms | Targets |
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T17881 | (S,R,S)-AHPC-C10-NH2 | VH032-C10-NH2 | Others , Ligand for E3 Ligase |
(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate, comprising the (S,R,S)-AHPC-based VHL ligand and a linker, designed for BET-targeted PROTAC applications. | |||
T17694 | Br-C10-methyl ester | Others , PROTAC Linker | |
Br-C10-methyl ester, a PROTAC linker characterized by its alkyl/ether composition, plays a crucial role in the synthesis of a series of PROTACs (MS432). This compound incorporates a dual-ligand system connected via a lin... | |||
T18669L | (S,R,S)-AHPC-Me-C10-NH2 hydrochloride | Ligand for E3 Ligase | |
(S,R,S)-AHPC-Me-C10-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating a VHL ligand and a linker. | |||
T39378 | Thalidomide-O-C10-NH2 | Thalidomide-O-C10-NH2 | |
Thalidomide-O-C10-NH2 is a synthetic E3 ligase ligand-linker conjugate combining a cereblon ligand derived from Thalidomide with a linker crucial for PROTAC technology. | |||
T40892 | Bromo-C10-OBn | Bromo-C10-OBn | |
Bromo-C10-OBn is a PROTAC linker that can be used in the synthesis of PROTACs. | |||
T38756 | Thiol-C10-amide-PEG8 | Thiol-C10-amide-PEG8 | |
Thiol-C10-amide-PEG8 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys... | |||
T41010 | Maleimide-C10-NHS ester | Maleimide-C10-NHS ester | |
Maleimide-C10-NHS ester is an alkyl/ether-based linker for PROTAC synthesis. | |||
T20499 | Norchlorcyclizine | C10,C-10,C 10 | Others |
Norchlorcyclizine (C-10) is a partially selective NPR-B inhibitor. It also is an inhibitor of human tyrosyl-DNA phosphodiesterase 1. | |||
T37739 | N-decanoyl-L-Homoserine lactone | C10-HSL,N-decanoyl-L-Homoserine lactone | Reactive Oxygen Species , Antibacterial |
N-decanoyl-L-Homoserine lactone (C10-HSL) is an N-acyl-homoserine lactone (AHL) produced by Pseudomonas cremoris strain ND07.N-decanoyl-L-homoserine lactone inhibits the growth of primary roots of Arabidopsis thaliana.N-... | |||
T18661 | (S,R,S)-AHPC-C10-NH2 dihydrochloride | VH032-C10-NH2 dihydrochloride,VH032-linker 10,VH032 amide-alkylC10-amine | Others , Ligand for E3 Ligase |
(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-linker 10) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker[1]. | |||
T18806 | Thalidomide-NH-C10-COOH | Others | |
Thalidomide-NH-C10-COOH (compound 6b) is a synthetic E3 ligase ligand-linker conjugate. This compound combines the Thalidomide-based von Hippel-Lindau (VHL) ligand with a linker commonly employed in PROTAC technology. [1... | |||
T17547 | Biotin-C10-NHS Ester | Others | |
Biotin-C10-NHS Ester is an alkyl/ether-based linker compound utilized in the synthesis of PROTACs[1]. | |||
T15930 | M-PEG8-C10-phosphonic acid | Others | |
m-PEG8-C10-phosphonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteaso... | |||
T18669 | (S,R,S)-AHPC-Me-C10-NH2 | Others | |
(S,R,S)-AHPC-Me-C10-NH2 is a chemical compound consisting of a synthesized E3 ligase ligand-linker conjugate that incorporates both a VHL ligand and a linker. This compound, (S,R,S)-AHPC-Me-C10-NH2, finds application in ... | |||
T18668 | (S,R,S)-AHPC-Me-C10-Br | Others | |
(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate that functions as a ligand-linker for E3 ligases. This compound incorporates a VHL E3 ligase linker and MS432, derived from the MEK1/2 inhibitor PD0325901[1]. | |||
T77957 | Thalidomide-5-O-C10-NH2 hydrochloride | ||
Thalidomide-5-O-C10-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein and, when linked to a protein ligand, forms PROTACs [1]. | |||
T74366 | 6BrCaQ-C10-TPP | ||
6BrCaQ-C10-TPP, a potent inhibitor of the mitochondrial heat shock protein TRAP1, exhibits antiproliferative activity against various human cancer cells, with an IC50 range of 0.008-0.30 μM. Additionally, it induces dist... | |||
T77980 | Pomalidomide-5-C10-NH2 hydrochloride | ||
Pomalidomide-5-C10-NH2 hydrochloride, a Pomalidomide-derived cereblon (CRBN) ligand, facilitates the recruitment of CRBN protein. This compound can be tethered to a protein ligand via a linker to construct a PROTAC [1]. | |||
T77984 | Thalidomide-NH-C10-NH2 hydrochloride | ||
Thalidomide-NH-C10-NH2 hydrochloride, a thalidomide-derived cereblon ligand, facilitates CRBN protein recruitment and, when conjugated with a linker, forms PROTACs [1]. | |||
T31513 | Dipentaerythrityl hexacaprate | dipentaerythritol hexacaprate,Dipentaerythrityl hexa C10 acid esters | |
Dipentaerythrityl hexacaprate is a biochemical. | |||
T77919 | Thalidomide-4-O-C10-NH2 hydrochloride | ||
Thalidomide-4-O-C10-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of the CRBN protein. This compound can be conjugated with a protein ligand via a linker to synthesize PROTACs [1]. | |||
T13254L | UNC10217938A HCl | UNC10217938A HCl(1347749-97-6 Free base),UNC7938 HCl | Others |
UNC10217938A HCl (UNC7938 HCl) is a 3-deazapteridine analog. UNC10217938A HCl exhibits strong oligonucleotide enhancing effects. UNC10217938A HCl can modulate their intracellular trafficking and release from endosomes, l... | |||
T38387 | Compound C108 | GTPase | |
Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2). Compound C108 can be used in studies about breast tumors and esophageal squamous cell carcinoma. | |||
T24706 | RBC10 | RBC 10,RBC-10 | GTPase |
RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines. | |||
T14694 | BNC105 | Microtubule Associated | |
BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties. | |||
T7001 | TIC10 | ONC-201 | Apoptosis , TNF |
TIC10 (ONC-201) inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2. | |||
T6705 | TIC10 Isomer | ONC201 isomer,TIC10 Analogue | Others |
TIC10 Isomer (ONC201 isomer) is an isomer of TIC10, which inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improv... | |||
T8827 | EMAC10101d | Carbonic Anhydrase | |
compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an inhibitory activity in the low nanomolar range. | |||
T8453 | UNC1079 | Epigenetic Reader Domain | |
UNC1079 is an selective L3MBTL3 domain inhibitor | |||
TP1663L | CysHHC10 acetate | CysHHC10 acetate(1408311-03-4 free base) | Antibacterial |
CysHHC10 acetate shows antibacterial activities against both Gram-positive and Gram-negative bacteria with MIC of 10.1, 20.2, 2.5, and 1.3 mM for E. coli, P. aeruginosa, S. aureus, and S. epidermidis, respectively. | |||
T8550 | NDMC101 | Others , NF-κB , Proteasome | |
NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 and NF-κB activity. | |||
T60794 | HDAC10-IN-1 | ||
HDAC10-IN-1 (compound 13b) is a potent and highly selective inhibitor of HDAC10 (IC 50 = 58 nM) that regulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells [1]. | |||
TF0051 | Anapoe-C10E9 | ||
Anapoe-C10E9 is a useful organic compound for research related to life sciences. The catalog number is TF0051 and the CAS number is 26183-52-81. | |||
T26935 | C108297 | C-108297,C 108297 | |
C108297 is a glucocorticoid receptor modulator. C108297 prevents both diet-induced obesity and inflammation. C108297 decreased food and fructose intake and increased lipolysis in white adipose tissue (WAT) and free fatty... | |||
T10361 | AR-C102222 hydrochloride | Others | |
AR-C102222 hydrochloride is a competitive, orally active, and highly selective inducible nitric oxide synthase (iNOS) inhibitor (IC50: 37 nM). It has antinociception and anti-inflammatory activities. | |||
T62097 | UNC10201652 | ||
UNC10201652 is a potent inhibitor of L1-specific intestinal bacterial β-glucuronidases (GUSs) and is able to act on Escherichia coli (E. coli) (IC50: 0.117 μM). glucuronide processing. | |||
T76036 | CysHHC10 TFA | ||
CysHHC10 TFA, a synthetic antimicrobial peptide (AMP), demonstrates potent effectiveness against a broad spectrum of bacteria, including both Gram-positive and Gram-negative strains. Specifically, Minimum Inhibitory Conc... | |||
T82546 | DiSBAC10 | ||
DiSBAC10, a voltage-sensitive fluorescent probe, facilitates cell membrane electrical activity investigation in FRET assays. At rest, it populates the membrane's outer leaflet, accepting photons from excited fluorescein-... | |||
T68273 | BNC105P | ||
BNC105P is a benzofuran-based vascular disrupting agent (VDA) prodrug with potential anti-vascular and antineoplastic activities. Upon administration vascular disrupting agent BNC105P, the disodium phosphate ester of BNC... | |||
TF0036 | Pentaethylene Glycol Monodecyl Ether (C10E5) | ||
Pentaethylene Glycol Monodecyl Ether (C10E5) is a useful organic compound for research related to life sciences. The catalog number is TF0036 and the CAS number is 23244-49-7. | |||
T68758 | UNC10112785 | ||
UNC10112785 is a novel potent inhibitor of CDK8, CDK19, and CDK9 with IC50 at 1.05, 2.67, and 19.9 nM, respectively, causing MYC loss through both transcriptional and posttranslational mechanisms, and suppressing PDAC an... | |||
T69496 | MCC1019 | ||
MCC1019 is a novel selective inhibitor of the Polo-box domain of Polo-like kinase 1 (PLK1). | |||
TF0030 | Hexaethylene Glycol Monodecyl Ether (C10E6) | ||
Hexaethylene Glycol Monodecyl Ether (C10E6) is a useful organic compound for research related to life sciences. The catalog number is TF0030 and the CAS number is 5168-89-8. | |||
T71727 | HC102A | ||
HC102A is an inhibitor of Mycobacterium tuberculosis DosRST signaling and persistence. | |||
T25884 | NSC103054 | NSC-103054,NSC 103054 | |
NSC103054 is an ABCG2 transporter function inhibitor. | |||
T69141 | NSC1008 | ||
NSC1008 is an inhibitor of the Ras Converting Enzyme 1 (Rce1) protease that disrupts Ras membrane localization in human cells. | |||
TP1663 | CysHHC10 | ||
CysHHC10 is a synthetic antimicrobial peptide (AMP), and exhibits strong anti-microbial properties against both Gram-positive and Gram-negative bacteria. | |||
TP1481 | Peptide C105Y | ||
C105Y, a synthetic peptide (CSIPPEVKFNKPFVYLI) based on the amino acid sequence corresponding to residues 359-374 of alpha1-antitrypsin, enhances gene expression from DNA nanoparticles. | |||
T78145 | HDAC10-IN-2 hydrochloride | Autophagy | |
HDAC10-IN-2 hydrochloride (compound 10c) is an HDAC10 inhibitor with high potency and selectivity, exhibiting an IC50 of 20 nM. It influences autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells [1]. | |||
T12114 | MSC1094308 | p97 | |
MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T81722 | N-(3-Oxodecanoyl)-L-homoserine lactone | 3-Oxo-C10-HSL | |
N-(3-Oxodecanoyl)-L-homoserine lactone (3-Oxo-C10-HSL) functions as a bacterial quorum-sensing signal autoinducer [1]. | |||
T1086 | Vitamin D2 | Calciferol,Ergocalciferol,Ercalciol | DNA/RNA Synthesis , Endogenous Metabolite |
Ergocalciferol (Vitamin D2 (Calciferol)) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond with a strong inhibitory effect against bladder tumor promotion by sodium saccharin, and it in... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02125 | CCL6 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Chemokine (C-C motif) ligand 6 (CCL6), also known as C-C chemokine C10 has only been identified in rodents, which is a small cytokine belonging to the CC chemokine family, beta-chemokine subfamily. C-C chemokine C10 is i... | |||
TMPY-02971 | CLEC10A Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CLEC10A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q8IUN9-2. | |||
TMPY-00820 | IgG1 Fc Protein, Human, Recombinant (C103S) | Human | HEK293 Cells |
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1. | |||
TMPH-00107 | UBC10 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | E. coli |
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. UBC10 Protein, Arabidopsis thaliana, Recombinant... | |||
TMPY-05138 | IgG1 Fc Protein, Human, Recombinant (C103S), Biotinylated | Human | HEK293 Cells |
IgG1 Fc Protein, Human, Recombinant (C103S), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.1 kDa and the accession number is AAC82527.1. | |||
TMPY-04103 | COLEC10 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 Cells |
COLEC1 is a member of the C-lectin family. Members of this family possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate anti... | |||
TMPY-06605 | IgG1 Fc Protein, Mouse, Recombinant (C102S) | Mouse | HEK293 Cells |
IgG1 Fc Protein, Mouse, Recombinant (C102S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.8 kDa and the accession number is AAK53870.1. | |||
TMPY-03996 | COLEC10 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
COLEC1 is a member of the C-lectin family. Members of this family possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate anti... | |||
TMPY-02459 | CLEC10A Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
CLEC10A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.7 kDa and the accession number is F8WHB7. | |||
TMPY-06893 | IgG1 Fc Protein, Human, Recombinant (C103S, Avi), Biotinylated | Human | HEK293 Cells |
IgG1 Fc Protein, Human, Recombinant (C103S, Avi), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 27.89 kDa and the accession number is AAC82527.1. | |||
TMPY-02405 | CLEC10A Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CLEC10A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.7 kDa and the accession number is F8WHB7. | |||
TMPJ-00201 | CLEC10A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
C-Type Lectin Domain Family 10 Member A (CLEC10A) is a type II transmembrane C-type lectin that is expressed on immature myleloid dendritic cells and alternatively activated (tolerogenic) macrophages. CLEC10A/MGL binds a... | |||
TMPH-00178 | AiiA Protein, Bacillus thuringiensis subsp., Recombinant (His & Myc) | Bacillus thuringiensis subsp. kurstaki | E. coli |
Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL. ... | |||
TMPH-02716 | HADH Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10). Plays a role in the control of insulin secretion ... | |||
TMPH-01410 | GPR84 Protein, Human, Recombinant (hFc) | Human | P. pastoris (Yeast) |
Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and ... |