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Search Results for " c10 "

Targets

62

Compounds

2

Natural Products

15

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T17881 (S,R,S)-AHPC-C10-NH2 VH032-C10-NH2 Others , Ligand for E3 Ligase
(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate, comprising the (S,R,S)-AHPC-based VHL ligand and a linker, designed for BET-targeted PROTAC applications.
T17694 Br-C10-methyl ester Others , PROTAC Linker
Br-C10-methyl ester, a PROTAC linker characterized by its alkyl/ether composition, plays a crucial role in the synthesis of a series of PROTACs (MS432). This compound incorporates a dual-ligand system connected via a lin...
T18669L (S,R,S)-AHPC-Me-C10-NH2 hydrochloride Ligand for E3 Ligase
(S,R,S)-AHPC-Me-C10-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating a VHL ligand and a linker.
T39378 Thalidomide-O-C10-NH2 Thalidomide-O-C10-NH2
Thalidomide-O-C10-NH2 is a synthetic E3 ligase ligand-linker conjugate combining a cereblon ligand derived from Thalidomide with a linker crucial for PROTAC technology.
T40892 Bromo-C10-OBn Bromo-C10-OBn
Bromo-C10-OBn is a PROTAC linker that can be used in the synthesis of PROTACs.
T38756 Thiol-C10-amide-PEG8 Thiol-C10-amide-PEG8
Thiol-C10-amide-PEG8 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys...
T41010 Maleimide-C10-NHS ester Maleimide-C10-NHS ester
Maleimide-C10-NHS ester is an alkyl/ether-based linker for PROTAC synthesis.
T20499 Norchlorcyclizine C10,C-10,C 10 Others
Norchlorcyclizine (C-10) is a partially selective NPR-B inhibitor. It also is an inhibitor of human tyrosyl-DNA phosphodiesterase 1.
T37739 N-decanoyl-L-Homoserine lactone C10-HSL,N-decanoyl-L-Homoserine lactone Reactive Oxygen Species , Antibacterial
N-decanoyl-L-Homoserine lactone (C10-HSL) is an N-acyl-homoserine lactone (AHL) produced by Pseudomonas cremoris strain ND07.N-decanoyl-L-homoserine lactone inhibits the growth of primary roots of Arabidopsis thaliana.N-...
T18661 (S,R,S)-AHPC-C10-NH2 dihydrochloride VH032-C10-NH2 dihydrochloride,VH032-linker 10,VH032 amide-alkylC10-amine Others , Ligand for E3 Ligase
(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-linker 10) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker[1].
T18806 Thalidomide-NH-C10-COOH Others
Thalidomide-NH-C10-COOH (compound 6b) is a synthetic E3 ligase ligand-linker conjugate. This compound combines the Thalidomide-based von Hippel-Lindau (VHL) ligand with a linker commonly employed in PROTAC technology. [1...
T17547 Biotin-C10-NHS Ester Others
Biotin-C10-NHS Ester is an alkyl/ether-based linker compound utilized in the synthesis of PROTACs[1].
T15930 M-PEG8-C10-phosphonic acid Others
m-PEG8-C10-phosphonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteaso...
T18669 (S,R,S)-AHPC-Me-C10-NH2 Others
(S,R,S)-AHPC-Me-C10-NH2 is a chemical compound consisting of a synthesized E3 ligase ligand-linker conjugate that incorporates both a VHL ligand and a linker. This compound, (S,R,S)-AHPC-Me-C10-NH2, finds application in ...
T18668 (S,R,S)-AHPC-Me-C10-Br Others
(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate that functions as a ligand-linker for E3 ligases. This compound incorporates a VHL E3 ligase linker and MS432, derived from the MEK1/2 inhibitor PD0325901[1].
T77957 Thalidomide-5-O-C10-NH2 hydrochloride
Thalidomide-5-O-C10-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein and, when linked to a protein ligand, forms PROTACs [1].
T74366 6BrCaQ-C10-TPP
6BrCaQ-C10-TPP, a potent inhibitor of the mitochondrial heat shock protein TRAP1, exhibits antiproliferative activity against various human cancer cells, with an IC50 range of 0.008-0.30 μM. Additionally, it induces dist...
T77980 Pomalidomide-5-C10-NH2 hydrochloride
Pomalidomide-5-C10-NH2 hydrochloride, a Pomalidomide-derived cereblon (CRBN) ligand, facilitates the recruitment of CRBN protein. This compound can be tethered to a protein ligand via a linker to construct a PROTAC [1].
T77984 Thalidomide-NH-C10-NH2 hydrochloride
Thalidomide-NH-C10-NH2 hydrochloride, a thalidomide-derived cereblon ligand, facilitates CRBN protein recruitment and, when conjugated with a linker, forms PROTACs [1].
T31513 Dipentaerythrityl hexacaprate dipentaerythritol hexacaprate,Dipentaerythrityl hexa C10 acid esters
Dipentaerythrityl hexacaprate is a biochemical.
T77919 Thalidomide-4-O-C10-NH2 hydrochloride
Thalidomide-4-O-C10-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of the CRBN protein. This compound can be conjugated with a protein ligand via a linker to synthesize PROTACs [1].
T13254L UNC10217938A HCl UNC10217938A HCl(1347749-97-6 Free base),UNC7938 HCl Others
UNC10217938A HCl (UNC7938 HCl) is a 3-deazapteridine analog. UNC10217938A HCl exhibits strong oligonucleotide enhancing effects. UNC10217938A HCl can modulate their intracellular trafficking and release from endosomes, l...
T38387 Compound C108 GTPase
Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2). Compound C108 can be used in studies about breast tumors and esophageal squamous cell carcinoma.
T24706 RBC10 RBC 10,RBC-10 GTPase
RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines.
T14694 BNC105 Microtubule Associated
BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.
T7001 TIC10 ONC-201 Apoptosis , TNF
TIC10 (ONC-201) inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
T6705 TIC10 Isomer ONC201 isomer,TIC10 Analogue Others
TIC10 Isomer (ONC201 isomer) is an isomer of TIC10, which inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improv...
T8827 EMAC10101d Carbonic Anhydrase
compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an inhibitory activity in the low nanomolar range.
T8453 UNC1079 Epigenetic Reader Domain
UNC1079 is an selective L3MBTL3 domain inhibitor
TP1663L CysHHC10 acetate CysHHC10 acetate(1408311-03-4 free base) Antibacterial
CysHHC10 acetate shows antibacterial activities against both Gram-positive and Gram-negative bacteria with MIC of 10.1, 20.2, 2.5, and 1.3 mM for E. coli, P. aeruginosa, S. aureus, and S. epidermidis, respectively.
T8550 NDMC101 Others , NF-κB , Proteasome
NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 and NF-κB activity.
T60794 HDAC10-IN-1
HDAC10-IN-1 (compound 13b) is a potent and highly selective inhibitor of HDAC10 (IC 50 = 58 nM) that regulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells [1].
TF0051 Anapoe-C10E9
Anapoe-C10E9 is a useful organic compound for research related to life sciences. The catalog number is TF0051 and the CAS number is 26183-52-81.
T26935 C108297 C-108297,C 108297
C108297 is a glucocorticoid receptor modulator. C108297 prevents both diet-induced obesity and inflammation. C108297 decreased food and fructose intake and increased lipolysis in white adipose tissue (WAT) and free fatty...
T10361 AR-C102222 hydrochloride Others
AR-C102222 hydrochloride is a competitive, orally active, and highly selective inducible nitric oxide synthase (iNOS) inhibitor (IC50: 37 nM). It has antinociception and anti-inflammatory activities.
T62097 UNC10201652
UNC10201652 is a potent inhibitor of L1-specific intestinal bacterial β-glucuronidases (GUSs) and is able to act on Escherichia coli (E. coli) (IC50: 0.117 μM). glucuronide processing.
T76036 CysHHC10 TFA
CysHHC10 TFA, a synthetic antimicrobial peptide (AMP), demonstrates potent effectiveness against a broad spectrum of bacteria, including both Gram-positive and Gram-negative strains. Specifically, Minimum Inhibitory Conc...
T82546 DiSBAC10
DiSBAC10, a voltage-sensitive fluorescent probe, facilitates cell membrane electrical activity investigation in FRET assays. At rest, it populates the membrane's outer leaflet, accepting photons from excited fluorescein-...
T68273 BNC105P
BNC105P is a benzofuran-based vascular disrupting agent (VDA) prodrug with potential anti-vascular and antineoplastic activities. Upon administration vascular disrupting agent BNC105P, the disodium phosphate ester of BNC...
TF0036 Pentaethylene Glycol Monodecyl Ether (C10E5)
Pentaethylene Glycol Monodecyl Ether (C10E5) is a useful organic compound for research related to life sciences. The catalog number is TF0036 and the CAS number is 23244-49-7.
T68758 UNC10112785
UNC10112785 is a novel potent inhibitor of CDK8, CDK19, and CDK9 with IC50 at 1.05, 2.67, and 19.9 nM, respectively, causing MYC loss through both transcriptional and posttranslational mechanisms, and suppressing PDAC an...
T69496 MCC1019
MCC1019 is a novel selective inhibitor of the Polo-box domain of Polo-like kinase 1 (PLK1).
TF0030 Hexaethylene Glycol Monodecyl Ether (C10E6)
Hexaethylene Glycol Monodecyl Ether (C10E6) is a useful organic compound for research related to life sciences. The catalog number is TF0030 and the CAS number is 5168-89-8.
T71727 HC102A
HC102A is an inhibitor of Mycobacterium tuberculosis DosRST signaling and persistence.
T25884 NSC103054 NSC-103054,NSC 103054
NSC103054 is an ABCG2 transporter function inhibitor.
T69141 NSC1008
NSC1008 is an inhibitor of the Ras Converting Enzyme 1 (Rce1) protease that disrupts Ras membrane localization in human cells.
TP1663 CysHHC10
CysHHC10 is a synthetic antimicrobial peptide (AMP), and exhibits strong anti-microbial properties against both Gram-positive and Gram-negative bacteria.
TP1481 Peptide C105Y
C105Y, a synthetic peptide (CSIPPEVKFNKPFVYLI) based on the amino acid sequence corresponding to residues 359-374 of alpha1-antitrypsin, enhances gene expression from DNA nanoparticles.
T78145 HDAC10-IN-2 hydrochloride Autophagy
HDAC10-IN-2 hydrochloride (compound 10c) is an HDAC10 inhibitor with high potency and selectivity, exhibiting an IC50 of 20 nM. It influences autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells [1].
T12114 MSC1094308 p97
MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase.

Compounds

(S,R,S)-AHPC-C10-NH2
T17881
Synonym: VH032-C10-NH2
Target: Others, Ligand for E3 Ligase
Br-C10-methyl ester
T17694
Synonym:
Target: Others, PROTAC Linker
(S,R,S)-AHPC-Me-C10-NH2 hydrochloride
T18669L
Synonym:
Target: Ligand for E3 Ligase
Thalidomide-O-C10-NH2
T39378
Synonym: Thalidomide-O-C10-NH2
Target:
Bromo-C10-OBn
T40892
Synonym: Bromo-C10-OBn
Target:
Thiol-C10-amide-PEG8
T38756
Synonym: Thiol-C10-amide-PEG8
Target:
Maleimide-C10-NHS ester
T41010
Synonym: Maleimide-C10-NHS ester
Target:
Norchlorcyclizine
T20499
Synonym: C10,C-10,C 10
Target: Others
N-decanoyl-L-Homoserine lactone
T37739
Synonym: C10-HSL,N-decanoyl-L-Homoserine lactone
Target: Reactive Oxygen Species, Antibacterial
(S,R,S)-AHPC-C10-NH2 dihydrochloride
T18661
Synonym: VH032-C10-NH2 dihydrochloride,VH032-linker 10,VH032 amide-alkylC10-amine
Target: Others, Ligand for E3 Ligase
Thalidomide-NH-C10-COOH
T18806
Synonym:
Target: Others
Biotin-C10-NHS Ester
T17547
Synonym:
Target: Others
m-PEG8-C10-phosphonic acid
T15930
Synonym:
Target: Others
(S,R,S)-AHPC-Me-C10-NH2
T18669
Synonym:
Target: Others
(S,R,S)-AHPC-Me-C10-Br
T18668
Synonym:
Target: Others
Thalidomide-5-O-C10-NH2 hydrochloride
T77957
Synonym:
Target:
6BrCaQ-C10-TPP
T74366
Synonym:
Target:
Pomalidomide-5-C10-NH2 hydrochloride
T77980
Synonym:
Target:
Thalidomide-NH-C10-NH2 hydrochloride
T77984
Synonym:
Target:
Dipentaerythrityl hexacaprate
T31513
Synonym: dipentaerythritol hexacaprate,Dipentaerythrityl hexa C10 acid esters
Target:
Thalidomide-4-O-C10-NH2 hydrochloride
T77919
Synonym:
Target:
UNC10217938A HCl
T13254L
Synonym: UNC10217938A HCl(1347749-97-6 Free base),UNC7938 HCl
Target: Others
Compound C108
T38387
Synonym:
Target: GTPase
RBC10
T24706
Synonym: RBC 10,RBC-10
Target: GTPase
BNC105
T14694
Synonym:
Target: Microtubule Associated
TIC10
T7001
Synonym: ONC-201
Target: Apoptosis, TNF
TIC10 Isomer
T6705
Synonym: ONC201 isomer,TIC10 Analogue
Target: Others
EMAC10101d
T8827
Synonym:
Target: Carbonic Anhydrase
UNC1079
T8453
Synonym:
Target: Epigenetic Reader Domain
CysHHC10 acetate
TP1663L
Synonym: CysHHC10 acetate(1408311-03-4 free base)
Target: Antibacterial
NDMC101
T8550
Synonym:
Target: Others, NF-κB, Proteasome
HDAC10-IN-1
T60794
Synonym:
Target:
Anapoe-C10E9
TF0051
Synonym:
Target:
C108297
T26935
Synonym: C-108297,C 108297
Target:
AR-C102222 hydrochloride
T10361
Synonym:
Target: Others
UNC10201652
T62097
Synonym:
Target:
CysHHC10 TFA
T76036
Synonym:
Target:
DiSBAC10
T82546
Synonym:
Target:
BNC105P
T68273
Synonym:
Target:
Pentaethylene Glycol Monodecyl Ether (C10E5)
TF0036
Synonym:
Target:
UNC10112785
T68758
Synonym:
Target:
MCC1019
T69496
Synonym:
Target:
Hexaethylene Glycol Monodecyl Ether (C10E6)
TF0030
Synonym:
Target:
HC102A
T71727
Synonym:
Target:
NSC103054
T25884
Synonym: NSC-103054,NSC 103054
Target:
NSC1008
T69141
Synonym:
Target:
CysHHC10
TP1663
Synonym:
Target:
Peptide C105Y
TP1481
Synonym:
Target:
HDAC10-IN-2 hydrochloride
T78145
Synonym:
Target: Autophagy
MSC1094308
T12114
Synonym:
Target: p97
1 2
Cat No. Product Name Synonyms Targets
T81722 N-(3-Oxodecanoyl)-L-homoserine lactone 3-Oxo-C10-HSL
N-(3-Oxodecanoyl)-L-homoserine lactone (3-Oxo-C10-HSL) functions as a bacterial quorum-sensing signal autoinducer [1].
T1086 Vitamin D2 Calciferol,Ergocalciferol,Ercalciol DNA/RNA Synthesis , Endogenous Metabolite
Ergocalciferol (Vitamin D2 (Calciferol)) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond with a strong inhibitory effect against bladder tumor promotion by sodium saccharin, and it in...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02125 CCL6 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Chemokine (C-C motif) ligand 6 (CCL6), also known as C-C chemokine C10 has only been identified in rodents, which is a small cytokine belonging to the CC chemokine family, beta-chemokine subfamily. C-C chemokine C10 is i...
TMPY-02971 CLEC10A Protein, Human, Recombinant (hFc) Human HEK293 Cells
CLEC10A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q8IUN9-2.
TMPY-00820 IgG1 Fc Protein, Human, Recombinant (C103S) Human HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPH-00107 UBC10 Protein, Arabidopsis thaliana, Recombinant (His) Arabidopsis thaliana E. coli
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. UBC10 Protein, Arabidopsis thaliana, Recombinant...
TMPY-05138 IgG1 Fc Protein, Human, Recombinant (C103S), Biotinylated Human HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.1 kDa and the accession number is AAC82527.1.
TMPY-04103 COLEC10 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293 Cells
COLEC1 is a member of the C-lectin family. Members of this family possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate anti...
TMPY-06605 IgG1 Fc Protein, Mouse, Recombinant (C102S) Mouse HEK293 Cells
IgG1 Fc Protein, Mouse, Recombinant (C102S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.8 kDa and the accession number is AAK53870.1.
TMPY-03996 COLEC10 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
COLEC1 is a member of the C-lectin family. Members of this family possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate anti...
TMPY-02459 CLEC10A Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
CLEC10A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.7 kDa and the accession number is F8WHB7.
TMPY-06893 IgG1 Fc Protein, Human, Recombinant (C103S, Avi), Biotinylated Human HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S, Avi), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 27.89 kDa and the accession number is AAC82527.1.
TMPY-02405 CLEC10A Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
CLEC10A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.7 kDa and the accession number is F8WHB7.
TMPJ-00201 CLEC10A Protein, Human, Recombinant (His) Human HEK293 Cells
C-Type Lectin Domain Family 10 Member A (CLEC10A) is a type II transmembrane C-type lectin that is expressed on immature myleloid dendritic cells and alternatively activated (tolerogenic) macrophages. CLEC10A/MGL binds a...
TMPH-00178 AiiA Protein, Bacillus thuringiensis subsp., Recombinant (His & Myc) Bacillus thuringiensis subsp. kurstaki E. coli
Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL. ...
TMPH-02716 HADH Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10). Plays a role in the control of insulin secretion ...
TMPH-01410 GPR84 Protein, Human, Recombinant (hFc) Human P. pastoris (Yeast)
Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and ...
CCL6 Protein, Mouse, Recombinant (His)
TMPY-02125
Species: Mouse
Expression System: HEK293 Cells
CLEC10A Protein, Human, Recombinant (hFc)
TMPY-02971
Species: Human
Expression System: HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S)
TMPY-00820
Species: Human
Expression System: HEK293 Cells
UBC10 Protein, Arabidopsis thaliana, Recombinant (His)
TMPH-00107
Species: Arabidopsis thaliana
Expression System: E. coli
IgG1 Fc Protein, Human, Recombinant (C103S), Biotinylated
TMPY-05138
Species: Human
Expression System: HEK293 Cells
COLEC10 Protein, Cynomolgus, Recombinant (hFc)
TMPY-04103
Species: Cynomolgus
Expression System: HEK293 Cells
IgG1 Fc Protein, Mouse, Recombinant (C102S)
TMPY-06605
Species: Mouse
Expression System: HEK293 Cells
COLEC10 Protein, Mouse, Recombinant (hFc)
TMPY-03996
Species: Mouse
Expression System: HEK293 Cells
CLEC10A Protein, Mouse, Recombinant (hFc)
TMPY-02459
Species: Mouse
Expression System: HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S, Avi), Biotinylated
TMPY-06893
Species: Human
Expression System: HEK293 Cells
CLEC10A Protein, Mouse, Recombinant (His)
TMPY-02405
Species: Mouse
Expression System: HEK293 Cells
CLEC10A Protein, Human, Recombinant (His)
TMPJ-00201
Species: Human
Expression System: HEK293 Cells
AiiA Protein, Bacillus thuringiensis subsp., Recombinant (His & Myc)
TMPH-00178
Species: Bacillus thuringiensis subsp. kurstaki
Expression System: E. coli
HADH Protein, Mouse, Recombinant (His & SUMO)
TMPH-02716
Species: Mouse
Expression System: E. coli
GPR84 Protein, Human, Recombinant (hFc)
TMPH-01410
Species: Human
Expression System: P. pastoris (Yeast)
TargetMol