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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP2134 | c-JUN peptide | ||
Peptide comprising residues 33 - 57 of the JNK binding (δ) domain of human c-Jun. Disrupts JNK/c-Jun interaction leading to inhibition of serum-induced c-Jun phosphorylation, up-regulation of p21cip/waf and modulation of... | |||
T33467 | MOMIPP | PI3K | |
MOMIPP is a PIKfyve inhibitor and a macropinocytosis inducer. MOMIPP readily penetrates the blood-brain barrier and is moderately effective in suppressing progression of intracerebral glioblastoma xenografts[1][2]. | |||
T12189 | NBDHEX | Apoptosis , Glutathione Peroxidase , Autophagy | |
NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) . | |||
T9688 | CC-90001 | JNK | |
CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2. | |||
T9052 | XL092 | CL-092,JUN04542 | VEGFR , c-Met/HGFR , TAM Receptor |
XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders. | |||
T5097 | Ezatiostat | TER199(free base),TLK199 | Apoptosis , Glutathione Peroxidase , GST |
Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity. | |||
T0518 | Methacycline hydrochloride | Rondomycin,Methacycline HCl | ribosome , Antibacterial , Antibiotic |
Methacycline hydrochloride (Rondomycin) is a broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels for a more extended period. | |||
T9010 | IMM-H007 | Others , AMPK | |
IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression | |||
T22776 | Ezatiostat hydrochloride | TLK199 HCl,TER199 | Glutathione Peroxidase |
Ezatiostat hydrochloride (TLK199 HCl) is an effective inhibitor of glutathione S-transferase. Ezatiostat hydrochloride is a novel glutathione analog and the potential treatment of cytopenias. In addition, Ezatiostat hydr... | |||
T2343 | AS601245 | JNK | |
AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties. | |||
T3755 | Pinostilbene | Others | |
Pinostilbene obviously attenuates the phosphorylation of c-Jun and JNK triggered by 6-OHDA. | |||
TP1897L1 | JIP-1 (153-163) acetate(438567-88-5 free base) | JNK | |
JIP-1 (153-163) acetate is a peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). | |||
T3892 | Isoacteoside | Isoverbascoside | NF-κB |
Isoacteoside has the anti-inflammatory effect, mediated by action on caspase-1, mitogen-activated protein kinases (c-Jun N-terminal kinase, p38, extracellular signal-regulated protein kinase) and nuclear factor-kappa B p... | |||
T5416 | T-5224 | MMP | |
T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors. | |||
T5833 | CC-401 Hydrochloride | CC401 HCl | JNK |
CC-401 Hydrochloride (CC401 HCl) is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor (Ki of 25 to 50 nM.)with potential antineoplastic activity. | |||
T16436 | PBOX 6 | PBOX-6 | Apoptosis |
PBOX 6 is a pyrrolo-1,5-benzoxazepine (PBOX) compound with anticancer and antitumor activity that inhibits breast cancer cell growth in vitro and selectively induces apoptosis in leukemia cells via c-Jun NH2 terminal kin... | |||
T3598 | JNK-IN-7 | JNK inhibitor | JNK |
JNK-IN-7 (JNK inhibitor) is a selective JNK1/2/3 inhibitor (IC50: 1.54/1.99/0.75 nM). It can also inhibit phosphorylation of c-Jun, which is a substrate of JNK kinase. | |||
T7677 | JNK Inhibitor VIII | TCS JNK 6o | JNK |
JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively). | |||
T68060 | Elgodipine | ||
Elgodipine significantly reduced the incidence and severity of exercise-induced angina pectoris systemically and was able to inhibit vascular smooth muscle proliferation through a mechanism independent of the expression ... | |||
T3908 | 10-Gingerol | Apoptosis | |
10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase (JNK), and extracellular signal-regulated kinase (ERK). |