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Search Results for " antipruritic "

20

Compounds

Cat No. Product Name Synonyms Targets
T11723L JNJ-39758979 Histamine Receptor
JNJ-39758979 is a selective and high-affinity histamine H4 receptor antagonist (Kis: 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively). JNJ-39758979 functionally antagonizes histamine...
T1278 Astemizole Laridal,Histaminos,Paralergin Potassium Channel , Histamine Receptor
Astemizole (Laridal) is a synthetic piperidinyl-benzimidazol derivative with antiallergic properties, acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to re...
T0370 Pheniramine maleate Daneral,Inhiston,Trimetose 5-HT Receptor , Histamine Receptor
Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re...
T21014 Thonzylamine hydrochloride Resistab,Thonzylamine HCl,Novohetramin,Neohetramine hydrochloride,Anahist AChR , Histamine Receptor
Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.
T21443 Prednicarbate Hoe 777,Hoe-777,Dermatop E emollient,UNII-V901LV1K7D Others
Prednicarbate (Hoe 777) is a Corticosteroid Hormone Receptor Agonist. Prednicarbate has antipruritic, anti-inflammatory, and vasoconstrictive properties. It also decreases the number of circulating lymphocytes by inhibit...
T0276 Hydrocortisone Valerate Westcort Glucocorticoid Receptor
Hydrocortisone Valerate (Westcort) has anti-inflammatory, antipruritic and vasoconstrictive properties.
T7564 Chlorphenoxamine Contristamine Histamine Receptor
Chlorphenoxamine (Contristamine) is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent.
T0270 Hydrocortisone 17-butyrate Cortisol 17-butyrate,Hydrocortisone butyrate Glucocorticoid Receptor , Annexin A , Adrenergic Receptor
Hydrocortisone 17-butyrate (Cortisol 17-butyrate) is a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects.
T0460 Pramocaine hydrochloride Pramoxine hydrochloride,Pramoxine HCl Sodium Channel
Pramocaine hydrochloride (Pramoxine HCl), a topical anesthetic, is served as an antipruritic.
T20802 Flumethasone pivalate Locacorten,NSC-107680,Lorinden,NSC 107680,NSC107680,Locorten Others
Flumethasone pivalate (Locorten) has antipruritic, anti-inflammatory, and vasoconstrictive properties and can be used in studies about adrenocortical suppression, cutaneous atrophy, plasma transcortin binding, and telang...
T21361 Alclometasone dipropionate Vaderm,Sch 22219,Aclovate,Delonal Others
Alclometasone dipropionate (Sch 22219) is a synthetic glucocorticoid, a steroidal compound with antiproliferative, anti-inflammatory, anti-allergic, antipruritic, and vasoconstrictive properties, which is used in the stu...
T1124 Flumethasone Flumetasone,RS-2177,NSC-54702 Glucocorticoid Receptor
Flumethasone (RS-2177) is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.
T3282 Alimemazine hemitartrate Alimemazine Tartrate,Methylpromazine Tartrate,Trimeprazine tartrate,Trimeprazine hemitartrate Others
Alimemazine hemitartrate (Trimeprazine hemitartrate) is aphenothiazine derivative that is used as an antipruritic. It also acts as a sedative, hypnotic, and antiemetic for prevention of motion sickness.
T2952 Camphor (±)-Camphor,Bornan-2-one,2-Camphanone,2-Bornanone,Formosa Influenza Virus , TRP/TRPV Channel
Camphor (2-Camphanone) is a bicyclic monoterpene ketone found widely in plants, especially CINNAMOMUM CAMPHORA. It is used topically as a skin antipruritic and as an anti-infective agent.
T0376 Crotamiton Eurax,Crotamitone,Veteusan Parasite
Crotamiton (Eurax) is an antipruritic and a scabicidal agent available as a lotion or cream for topical use only. It is a colorless to slightly yellowish oil with a faint amine-like odor. It is miscible with methanol and...
T1198 Tetracaine hydrochloride Amethocaine hydrochloride,Amethocalne HCl,Tetracaine HCl Calcium Channel , Sodium Channel
Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been use...
T1561 Clobetasol propionate Dermovate,Clobetasol 17-propionate,CGP9555,Temovate,CCl 4725 Glucocorticoid Receptor , P450
Clobetasol propionate (CGP9555) exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expression. This results in the synthesis of certain a...
T6529 Halobetasol propionate Halobetasol Propionate,Ulobetasol propionate,BMY-30056,CGP-14458 Phospholipase
Halobetasol propionate (BMY-30056) is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses acr...
T23944 DA 5018 DA-5018,DA5018
DA 5018 is a capsaicin derivative and is also a new non-narcotic analgesic. It has an antipruritic effect.
T10281 Alimemazine Trimeprazine Others
Alimemazine (Trimeprazine) is generally used as an antipruritic agent and also a hemagglutinin (HA)-receptor antagonist. Alimemazine also acts as a partial agonist against the histamine H1 receptor (H1R) and other GPCRs.

Compounds

JNJ-39758979
T11723L
Synonym:
Target: Histamine Receptor
Astemizole
T1278
Synonym: Laridal,Histaminos,Paralergin
Target: Potassium Channel, Histamine Receptor
Pheniramine maleate
T0370
Synonym: Daneral,Inhiston,Trimetose
Target: 5-HT Receptor, Histamine Receptor
Thonzylamine hydrochloride
T21014
Synonym: Resistab,Thonzylamine HCl,Novohetramin,Neohetramine hydrochloride,Anahist
Target: AChR, Histamine Receptor
Prednicarbate
T21443
Synonym: Hoe 777,Hoe-777,Dermatop E emollient,UNII-V901LV1K7D
Target: Others
Hydrocortisone Valerate
T0276
Synonym: Westcort
Target: Glucocorticoid Receptor
Chlorphenoxamine
T7564
Synonym: Contristamine
Target: Histamine Receptor
Hydrocortisone 17-butyrate
T0270
Synonym: Cortisol 17-butyrate,Hydrocortisone butyrate
Target: Glucocorticoid Receptor, Annexin A, Adrenergic Receptor
Pramocaine hydrochloride
T0460
Synonym: Pramoxine hydrochloride,Pramoxine HCl
Target: Sodium Channel
Flumethasone pivalate
T20802
Synonym: Locacorten,NSC-107680,Lorinden,NSC 107680,NSC107680,Locorten
Target: Others
Alclometasone dipropionate
T21361
Synonym: Vaderm,Sch 22219,Aclovate,Delonal
Target: Others
Flumethasone
T1124
Synonym: Flumetasone,RS-2177,NSC-54702
Target: Glucocorticoid Receptor
Alimemazine hemitartrate
T3282
Synonym: Alimemazine Tartrate,Methylpromazine Tartrate,Trimeprazine tartrate,Trimeprazine hemitartrate
Target: Others
Camphor
T2952
Synonym: (±)-Camphor,Bornan-2-one,2-Camphanone,2-Bornanone,Formosa
Target: Influenza Virus, TRP/TRPV Channel
Crotamiton
T0376
Synonym: Eurax,Crotamitone,Veteusan
Target: Parasite
Tetracaine hydrochloride
T1198
Synonym: Amethocaine hydrochloride,Amethocalne HCl,Tetracaine HCl
Target: Calcium Channel, Sodium Channel
Clobetasol propionate
T1561
Synonym: Dermovate,Clobetasol 17-propionate,CGP9555,Temovate,CCl 4725
Target: Glucocorticoid Receptor, P450
Halobetasol propionate
T6529
Synonym: Halobetasol Propionate,Ulobetasol propionate,BMY-30056,CGP-14458
Target: Phospholipase
DA 5018
T23944
Synonym: DA-5018,DA5018
Target:
Alimemazine
T10281
Synonym: Trimeprazine
Target: Others
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TargetMol