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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T31011 | Coralyne chloride | Topoisomerase | |
Coralyne chloride is a protoberberine with strong anticancer activity. It can be used to prepare Coralyne derivatives, a fluorescent DNA-based molecular rectifier built into DNA duplexes through site-specific insertion. ... | |||
T24269 | KPT-251 | KPT251 | Others |
KPT-251 is a selective nuclear export inhibitor. | |||
T8308 | NL-1 | Mitochondrial Metabolism , Autophagy | |
NL-1 is a mitoNEET inhibitor with antileukemic effect. | |||
T7673 | ATH686 | ATH 686 | Apoptosis , FLT |
ATH686 is an potent and selective Inhibitor of FLT3. | |||
TN4673 | (+)-Nortrachelogenin | Wikstromol | Apoptosis , HIV Protease , PI3K , Antifection |
(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity. | |||
TN1932 | Microhelenin C | Others | |
Microhelenin C has significant antileukemic activity. | |||
T27704 | K00135 | K-00135,Imidazol[1,2-b]pyridazine 1,K 00135,IMIDAZOPYRIDAZIN 1 | Pim |
K00135 (IMIDAZOPYRIDAZIN 1) is a selective inhibitor of Pim kinases and can be used in studies about gastric cancer and antileukemic therapeutics. | |||
T15235 | Enocitabine | Nucleoside Antimetabolite/Analog , HCV Protease , DNA/RNA Synthesis | |
Enocitabine is a nucleoside analog. Enocitabine inhibits the replication of human cytomegalovirus(HCMV) and it also has antileukemic and antiviral activities. Enocitabine is also a potent DNA replication inhibitor and a ... | |||
T16940 | STAT5-IN-2 | Apoptosis , STAT | |
STAT5-IN-2 is an inhibitor of STAT5 with antileukemic effects (EC50s: 9 μM and 5 μM in K562 and KU812 cells, respectively). | |||
T5S1058 | Triptonide | PG 492,NSC 165677 | Apoptosis , Wnt/beta-catenin , Autophagy |
1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, an... | |||
T4409 | Gilteritinib | ASP2215 | FLT , TAM Receptor , c-Kit |
Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively). In preClinicalal studies, gilteritinib showed strong an... | |||
T24978 | 5,10-Dideazaaminopterin | ||
5,10-Dideazaaminopterin is an antileukemic drug. | |||
TN2320 | Yadanzioside G | Others | |
Yadanzioside G has antileukemic activity. | |||
TN5266 | Yadanzioside F | Others | |
Yadanzioside F has antileukemic activity. | |||
TN5092 | Tagitinin F | Antifection | |
Tagitinin F possesses antileukemic activity; it also shows in vitro leishmanicidal activities against Leishmania braziliensis promastigotes and amastigotes. | |||
T25503 | Hisphen | Synonyms Hisfen,MD 2 | |
Hisphen shows antileukemic activity. | |||
T24979 | 5,10-Dideazafolic acid | ||
5,10-Dideazafolic acid is an antileukemic drug. | |||
T15472 | Hepsulfam | NCI 329680,ZINC01574758 | Others |
Hepsulfam is an anticancer agent. It also displays excellent antileukemic activity (a median IC50: 0.91 μg/mL in a panel of different tumors). | |||
TN4027 | Eucannabinolide | Others | |
Eucannabinolide exhibits in vivo antileukemic activity. | |||
TN3796 | Dehydrobruceantinol | Others | |
Dehydrobruceantinol shows bitter taste and has antileukemic activity. |