anti-hbv — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN1482	Chamaechromone		P450 , HBV
	Chamaechromone is a natural product isolated from the roots of Stellera chamaejasme L.. Chamaechromone has anti-HBV and insecticidal activity.		P450 , HBV
T4S1718	Punicalin		HBV , HIV Protease
	Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg/ml (0.14 microM).		HBV , HIV Protease
T2780	Catalpol	Catalpinoside,Digitalis purpurea L	Others , HBV
	Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.		Others , HBV
T3921	Punicalagin		SARS-CoV , HBV
	Punicalagin is a major ellagitannin found in pomegranates that is reported to produce antioxidant, anti-inflammatory, and anticancer effects. It has been shown to prevent high-fat diet-induced obesity-associated accumula...		SARS-CoV , HBV
T4328	OSS_128167	SIRT6-IN-1	HBV , Sirtuin
	OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor, and for SIRT6(IC50=89 μM), SIRT1(IC50=1578 μM) and SIRT2(IC50=751 μM).		HBV , Sirtuin
T6439	Cetylpyridinium Chloride	Cetamium,Pristacin,Hexadecylpyridinium Chloride	Others , HBV , Antibacterial
	Cetylpyridinium Chloride (Hexadecylpyridinium Chloride) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.		Others , HBV , Antibacterial
T2S1158	4,5-Dicaffeoylquinic acid	3,4-Dicaffeoylquinic acid,Isochlorogenic acid C	Others , HBV , Endogenous Metabolite
	1. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) has antiviral activity, including anti-HIV-1 integrase activity. 2. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) shows anti-hepatotoxic activity.		Others , HBV , Endogenous Metabolite
T11550	Helioxanthin derivative 5-4-2	Helioxanthin 5-4-2	HBV
	Helioxanthin derivative 5-4-2 （Helioxanthin 5-4-2） is an analogue of helioxanthin that shows anti-HBV activity in vitro and can be used to study HBV.		HBV
T16366	NVR 3-778		HBV
	NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM belonging to the SBA class It has anti-HBV activity.		HBV
T8471	Vonafexor	EYP001,PLX007,pxl007	FXR , HBV
	Vonafexor (EYP001) is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effects		FXR , HBV
T11669	IR415		HBV
	IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx protein on the activity of the dicer endoribonuclease. IR415 i...		HBV
T4121	Bicyclol	SY801	HBV , Autophagy
	Bicyclol (SY801)(SY 801) is an anti-hepatitis drug. Oral administration of bicyclol normalizes the elevated serum transaminases (ALT, AST) by 50% in chronic viral hepatitis B and C, and also has a certain level of inhibi...		HBV , Autophagy
T67797	DDG-39	1-(2,3-dideoxy-2-fluoropentofuranosyl)cytosine	Antiviral , HBV , HIV Protease
	DDG-39 (1-(2,3-dideoxy-2-fluoropentofuranosyl)cytosine) possesses antiviral activity with potent and selective anti-HIV-1 and HBV activity in cell culture. The average antiviral IC50 is 0.61 μM.		Antiviral , HBV , HIV Protease
TN5845	Neochlorogenic acid methyl ester	5-O-Caffeoylquinic acid methyl ester,Methyl 3-caffeoylquinate,GIP (1-39) acetate(725474-97-5 Free base),Methyl neochlorogenate	Antioxidant , HBV
	Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) is derived from Artemisia capillaris and black chokeberry (Aronia melanocarpa) fruits. Neochlorogenic acid methyl ester shows weak anti-HBV activity...		Antioxidant , HBV
T3794	Pentagalloylglucose	Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose	Influenza Virus
	1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses poten...		Influenza Virus
T39043	Tenofovir amibufenamide	HS-10234	HBV
	Tenofovir amibufenamide (HS-10234) (HS-10234) is a Tenofovir prodrug, an antiviral compound with oral activity. Tenofovir amibufenamide inhibits hepatitis B virus (HBV) and can be used in chronic hepatitis B (CHB) studie...		HBV
T5S2254	Swertianolin	Bellidifolin-8-O-Glucoside	Others , HBV , Antibacterial , AChE
	1. Swertianolin (Bellidifolin-8-O-Glucoside), mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentianaceae species. 2. Swertianolin...		Others , HBV , Antibacterial , AChE
T26771	Bentysrepinine	Y 101,Y101,Y-101
	Bentysrepinine, a novel anti-HBV agent, inhibits DNA-HBV and cccDNA activities for the treatment of hepatitis B virus (HBV)-infected hepatitis.
T39744	Firzacorvir
	Firzacorvir is a cyclic sulfamide compound that acts as an HBV core protein modulator and exhibits potent anti-HBV activity, with an EC50 value of < 1 μΜ.
T61115	HBV-IN-25
	HBV-IN-25 is a novel chemical compound that acts as a potent HBV cccDNA reducer when administered orally. It exhibits significant anti-HBeAg potency and anti-HBV activity, with IC50 values of 0.58 μM and 1.15 μM, respect...