analgesia — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2524	Dexmedetomidine		Adrenergic Receptor
	Dexmedetomidine is a Central alpha-2 Adrenergic Agonist. The mechanism of action of dexmedetomidine is as an Adrenergic alpha2-Agonist. The physiologic effect of dexmedetomidine is by means of General Anesthesia.		Adrenergic Receptor
T6554	JZL 184	JZL184	Lipase
	JZL 184 is a potent and selective inhibitor of MAGL with IC50 of 8 nM and 4 μM for inhibition of MAGL and FAAH in mouse brain membranes respectively.		Lipase
T21422	Methylnaltrexone bromide	Relistor,MOA-728,MOA 728,Methylnaltrexone,MOA728	Opioid Receptor
	Methylnaltrexone bromide (MOA-728) is one of the newer agents of peripherally-acting μ-opioid antagonists. Methylnaltrexone bromide acts to reverse some of the side effects of opioid drugs such as constipation without af...		Opioid Receptor
T6579	Medetomidine hydrochloride	MPV785,Medetomidine HCl,Domitor	Adrenergic Receptor
	Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.		Adrenergic Receptor
T1780	Parecoxib	SC 69124,Vorth-P,Valus-P	COX
	Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.		COX
T6466	Dexmedetomidine hydrochloride	Precedex,(+)-Medetomidine hydrochloride,(S)-Medetomidine hydrochloride,Dexmedetomidine HCl	Adrenergic Receptor
	Dexmedetomidine hydrochloride (Precedex) is an imidazole derivative that is an agonist of the adrenergic alpha-2 receptor. It is closely-related to MEDETOMIDINE, which is the racemic form of this compound.		Adrenergic Receptor
T5691	Paulownin		Anti-infection
	Paulownin, a furofuran lignan from Paulownia tomentosa,has the action of anti-inflammation,analgesia,immunity,hypoglycemia and has little toxicity.		Anti-infection
T20172L	Kyotorphin acetate		Endogenous Metabolite , Antibacterial
	Kyotorphin acetate is an endogenous peptide with analgesia activity and can be used as a biomarker of Alzheimer disease.		Endogenous Metabolite , Antibacterial
T5734	(+)-BORNEOL	d-Borneol	GABA Receptor
	(+)-BORNEOL (d-Borneol) is a natural bicyclic monoterpene used for analgesia and anesthesia in traditional Chinese medicine; enhances GABA receptor activity with an EC50 of 248 μM.		GABA Receptor
T3834	8-Epideoxyloganic acid		ROS , Immunology/Inflammation related
	8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during oxidative stress, the inhibition of ROS production, possibl...		ROS , Immunology/Inflammation related
T50082	Org 25543		Chloride channel
	Org 25543 is the development of an N-Acyl amino acid that selectively inhibits the glycine transporter 2 to produce analgesia in a rat model of chronic pain.		Chloride channel
T6504	Flupirtine maleate	Katadolon maleate	Potassium Channel , NMDAR , iGluR
	Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. It is an NMDA receptor antagonist , and also a specific neuronal potassium channel opener.		Potassium Channel , NMDAR , iGluR
T0056	Oxeladin citrate		Others
	Oxeladin citrate is a highly potent and effective cough suppressant, which can treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment with oxeladin is no risk of add...		Others
T1787	Levobupivacaine		Sodium Channel
	Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZ...		Sodium Channel
T31541	D-Kyotorphin	H-L-Tyr-D-Arg-OH
	D-Kyotorphin is a synthetic neuropeptide kyotorphin analog that produces naloxone reversible analgesia.
T34152L	Propiomazine HCl	Propiomazine hydrochloride,Largon
	Propiomazine HCl is an analgesia adjunct.
T27888	LY 190388	LY190388,LY-190388
	LY 190388 is a penicillamine-containing enkephalin analog used as an mu receptor agonist with analgesia activity.
T70078	Fadolmidine
	Fadolmidine is a novel and potent alpha2 -adrenoceptor (alpha2) -AR) agonist developed for spinal analgesia.
T25675	Leucinal	L-Leucinal
	Leucinal inhibits the activity of brain aminopeptidase and potentiates analgesia induced by leu-enkephalen.
T32105	Cipepofol	HSK3486,HSK 3486,HSK-3486
	HSK3486 is similar to propofol and is a general anesthetic, which may have therapeutic potential in insomnia, migraine, anxiety, analgesia, and other aspects.