aldosterone — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19186	Aldosterone		Others
	Aldosterone is the primary mineralocorticoid. Aldosterone is synthesized and secreted in response to renin-angiotensin system activation or high dietary potassium by the zona glomerulosa of the adrenal cortex.		Others
T19185	Aldosterone-d8	Aldosterone D8	Others
	Aldosterone D8, a deuterium-labeled variant of Aldosterone produced in the adrenal zona glomerulosa, regulates blood pressure.		Others
T36381	Aldosterone 21-sulfate (sodium salt)
	Aldosterone 21-sulfate is a metabolite of the steroid hormone aldosterone .1It reduces the sodium-to-potassium ratio in rat urine when administered at doses ranging from 10 to 100 μg, indicating mineralocorticoid activit...
T29852	Aldosterone-3-(O-carboxymethyl)oximino-(2-iodohistamine)
	Aldosterone-3-(O-carboxymethyl)oximino-(2-iodohistamine) is a biochemical.
T4316	ML365		Potassium Channel
	ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).		Potassium Channel
T0293	Metyrapone	NSC-25265,Su-4885	Others , P450 , Dehydrogenase , Autophagy
	Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.		Others , P450 , Dehydrogenase , Autophagy
T1410	Torsemide	AC-4464,JDL-464,Torasemide	Na-K-Cl cotransporter
	Torsemide (AC-4464) is an anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and h...		Na-K-Cl cotransporter
T0083	Eplerenone	Epoxymexrenone,CGP 30083,SC-66110	Glucocorticoid Receptor
	Eplerenone (CGP 30083) is an aldosterone receptor antagonist and potassium-sparing diuretic used in the therapy of hypertension. Eplerenone therapy has been associated with transient elevations in serum aminotransferase ...		Glucocorticoid Receptor
T3033	Deoxycorticosterone acetate	DOC acetate,Cortexone acetate,11-Deoxycorticosterone acetate	Glucocorticoid Receptor , Endogenous Metabolite , Adrenergic Receptor
	Deoxycorticosterone acetate (Cortexone acetate) is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection for replacement therapy of the adrenocortical steroid.
T4277	Osilodrostat	LCI699	Glucocorticoid Receptor , Others , Hydroxylase
	Osilodrostat (LCI699) (LCI699) is an effective inhibitor of human 11β-hydroxylase (IC50: 2.5 nM) and aldosterone synthase (IC50: 0.7 nM).		Glucocorticoid Receptor , Others , Hydroxylase
T0354	Canrenone	6,7-Dehydro-7α-desthioacetylspironolactone,SC9376,Aldadiene,RP-11614,SC14266	Glucocorticoid Receptor , Endogenous Metabolite
	Canrenone (SC14266) is an aldosterone antagonist with potassium-sparing diuretic activity.		Glucocorticoid Receptor , Endogenous Metabolite
T0476	Spironolactone	SC9420,Abbolactone	Glucocorticoid Receptor , Androgen Receptor , Autophagy
	Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.		Glucocorticoid Receptor , Androgen Receptor , Autophagy
T13881	Dicirenone	SC26304	ATPase , Glucocorticoid Receptor
	Dicirenone (SC26304) inhibits the Mineralocorticoid receptor (MR), aldosterone regulation of the urinary K+:Na+ ratio, and aldosterone binding to renal cytoplasmic and nuclear receptors.		ATPase , Glucocorticoid Receptor
T61373	Baxdrostat		Others
	Baxdrostat is an aldosterone synthase inhibitor.		Others
T20302	Deoxycorticosterone	Desoxycorticosterone,Desoxycorticosteronum,Desoxycortone	Endogenous Metabolite
	Deoxycorticosterone (Desoxycortone) is a steroid metabolite produced by the adrenal gland. Deoxycorticosterone is an aldosterone precursor and possesses mineralocorticoid activity.		Endogenous Metabolite
T71664	Mespirenone		Others
	Mespirenone is a spironolactone derivative and aldosterone antagonist with diuretic effects.		Others
T3096	Canrenoate potassium	Potassium aldadiene,Canrenoic acid potassium salt,Potassium canrenoate,Soldactone	Glucocorticoid Receptor
	Canrenoate potassium (Soldactone) is a synthetic pregnadiene derivative with anti-aldosterone activity.		Glucocorticoid Receptor
T6262	Evacetrapib	LY2484595	CETP
	Evacetrapib (LY2484595) (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.		CETP
T1866	AT-56		Others , PGE Synthase
	AT56, a specific inhibitor of prostaglandin D2 synthase enzymatic activity, blunted adipogenic aldosterone effects.		Others , PGE Synthase
T7040	Angiotensin II human	DRVYIHPF,Angiotensin II,Hypertensin II,Ang II	Apoptosis , RAAS
	Angiotensin II human (Ang II) is a biologically active peptide, a vasoconstrictor. Angiotensin II interacts with AT1R and AT2R to regulate blood pressure, stimulate sympathetic nerves, and increase aldosterone biosynthes...		Apoptosis , RAAS