activity — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T13827	Pronase E (Activity ≥ 7000 U/g)	Pronase,Pronase E	Others
	Pronase E is a mixture of proteolytic enzymes that is obtained from Streptomyces griseus and could digest protein into individual amino acids.		Others
T60000	STING (WT/R232) activity regulator 126		STING
	STING (WT/R232) activity regulator 126 is a STING modulator with antibacterial and antiviral effects.		STING
T1292	Tiapride hydrochloride		Dopamine Receptor
	Tiapride is a selective blocker of D2/3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing dyskinesia, negative symptoms of psychosis, alcohol withdraw...		Dopamine Receptor
T2763	Panaxadiol	20(R)-Panaxadiol	Others , HIF/HIF Prolyl-Hydroxylase
	Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.		Others , HIF/HIF Prolyl-Hydroxylase
T3S1960	Kakuol		Antifungal
	1. Kakuol has antifungal activity, it can completely inhibit the mycelial growth of Botrytis cinerea Pers ex Fr and Cladosporium cucumerinum Ellis & Arthur at 5 microg ml(-1) and 3 microg ml(-1), respectively. 2. kakuol ...		Antifungal
TN6798	Progoitrin		Others
	Progoitrin is a biochemical from the glucosinolate family that is found in some food, which is inactive but after ingestion is converted to goitrin. Goitrin decreases the thyroid hormone production. Apart from goitrin, p...		Others
T15277	Fervenulin		Parasite
	Fervenulin is isolated from a nematicidal actinomycete Streptomyces sp. CMU-MH021 with nematicidal activity. It also inhibits egg hatch and J2 mortality of M. incognita (MICs: 30 μg/mL and 120 μg/mL, respectively).		Parasite
T5405	BI-1347		CDK
	BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.		CDK
TN1858	Leptomerine		AChE
	Leptomerine (IC50 = 2.5 mM) shows potent anticholinesterasic activity.		AChE
T37267	Pachybasin		Antibacterial
	Pachybasin is an anthraquinone fungal metabolite. Pachybasin shows antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and...		Antibacterial
T5S0106	Peimisine	Ebeiensine	RAAS , AChR
	1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe...		RAAS , AChR
T7934	7-Methylcoumarin		Others
	7-Methylcoumarin with strong hepatoprotective activity.		Others
T2230	Paeoniflorin	Peoniflorin	HSP , COX
	Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.		HSP , COX
T6S0923	Hypericin	Hypericine,Cyclosan	Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC
	1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL...
T8485	THIQ		Melanocortin Receptor
	THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively).		Melanocortin Receptor
TN1026	Vomicine		Others
	Vomicine is a natural product from Strychnos nux-vomica, the S. nux-vomica extracts show antihyperglycemic activity in experimental animals.		Others
T7898	AUDA		Epoxide Hydrolase
	AUDA is an inhibitor of sEH(IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively)		Epoxide Hydrolase
T9135	Epirosmanol		Others
	Epirosmanol is a diterpenoid containing a lactone moiety. Epirosmanol is a very weakly basic (essentially neutral) compound (based on its pKa).		Others
T23150	PHGDH-inactive		Others
	inactive analog of the 3-phosphoglycerate dehydrogenase (PHGDH) inhibitors NCT-502 and NCT-503		Others
T30937	Cimicoxib	UR-8880,UR8880,trade name: Cimalgex	COX
	Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.		COX