phosphatidylinositol — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T73812	Phosphatidylinositol 4,5-bisphosphate
	Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate), serving as a critical phospholipid in cell membranes, functions as a substrate for both phospholipase C (PLC) and phosphoinositide 3-...
T27499	GSK-A1		HCV Protease , PI4K
	GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression. GSK-A1 has anti-hepatitis C virus (HCV) potential.		HCV Protease , PI4K
TQ0009	UCB9608		PI4K
	UCB9608 is a selective and orally active PI4KIIIβ inhibitor (IC50: 11 nM), selective over PI3KC2 α, β, and γ lipid kinases.		PI4K
T16530	BF738735		Antiviral , PI4K
	BF738735 is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ, IC50 = 5.7 nM) showing higher activity over α(IC50 = 1.7 μM). BF738735 exhibits a broad spectrum of antiviral activity.		Antiviral , PI4K
T16125	MMV390048		Parasite , PI4K
	MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. fal...		Parasite , PI4K
T13386	Zandelisib		PI3K
	Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.		PI3K
T16967	T-00127_HEV1		PI4K
	T-00127_HEV1 is an inhibitor of phosphatidylinositol 4-kinase III beta (IC50: 60 nM).		PI4K
T12454	PI-273		Apoptosis , PI4K
	PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells		Apoptosis , PI4K
T12468	PI4KIIIbeta-IN-10		PI3K , PI4K
	PI4KIIIbeta-IN-10 is a potent inhibitor of PI4KIIIβ (IC50 of 3.6 nM).		PI3K , PI4K
T2616	PIK-93	PIK 93	ATM/ATR , DNA-PK , Virus Protease , PI3K , Carbonic Anhydrase , PI4K , mTOR , HSV
	PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.
T5421	KDU691		Parasite , PI4K
	KDU691 is a PI4K inhibitor.		Parasite , PI4K
T12469	PI4KIIIbeta-IN-9		PI3K , PI4K
	PI4KIIIbeta-IN-9 is a potent inhibitor of PI4KIIIβ(IC50 of 7 nM). .		PI3K , PI4K
T4220	BQR-695	BQR695,NVP-BQR695	PI3K , Parasite , PI4K
	BQR-695 (NVP-BQR695) is a phosphatidylinositol 4-kinase (PI4K) inhibitor with IC50s of 80 and 3.5 nM for human PI4KIIIβ and Plasmodium variant of PI4KIIIβ, respectively.		PI3K , Parasite , PI4K
T19840	GSK-F1	PI4KA inhibitor-F1	PI4K
	GSK-F1 (PI4KA inhibitor-F1) is a novel potent PI4KA inhibitor.		PI4K
T4079	LY-294002 hydrochloride	SF 1101,LY 294002,NSC 697286	PI3K
	LY-294002 hydrochloride (NSC 697286) is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in solution, and also is a blocker of autophagosome formation...		PI3K
T77212	L-α-lysophosphatidylinositol (Soy) (sodium)
	L-α-Lysophosphatidylinositol Soy Sodium, an endogenous ligand of GPR55, is an endocannabinoid neurotransmitter and lysophospholipid. This compound falls within the class of lysophospholipids [1].
T26698	AZ044		PI4K
	AZ044 is a potent, selective inhibitor of type III phosphatidylinositol-4-kinase alpha-subtype (PI4KIIIalpha).		PI4K
T26195	SMI481	NPPM-6748-481,NPPM 6748-481,NPPM6748481,SMI-481 SMI 481,NPPM 6748481	Others
	SMI481 (NPPM6748481) is the first small-molecule Sec14-like phosphatidylinositol transfer proteins (PITPs) inhibitor.		Others
T2061	APY0201		PI3K , Interleukin
	APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3, 5)P2.		PI3K , Interleukin
T12365	PARP/PI3K-IN-1		PARP , PI3K
	PARP/PI3K-IN-1 is a novel dual poly (ADP-ribose) polymerase (PARP) and phosphatidylinositol 3-kinase (PI3K) dual inhibitor with anticancer, antitumour and antiproliferative activities for the study of breast, pancreatic ...		PARP , PI3K