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UCB9608

Catalog No. TQ0009 CAS 1616413-96-7

UCB9608 is a selective and orally active PI4KIIIβ inhibitor (IC50: 11 nM), selective over PI3KC2 α, β, and γ lipid kinases.

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UCB9608, CAS 1616413-96-7

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	UCB9608 is a selective and orally active PI4KIIIβ inhibitor (IC50: 11 nM), selective over PI3KC2 α, β, and γ lipid kinases.
Targets&IC50	PI4KIIIβ:11 nM (cell free)

Molecular Weight	410.47
Formula	C20H26N8O2
CAS No.	1616413-96-7

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 60 mg/mL (146.18 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Reuberson J, et al. Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo. J Med Chem. 2018 Aug 9;61(15):6705-6723.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Anti-Lung Cancer Compound Library HIF-1 Signaling Pathway Compound Library Anti-Pancreatic Cancer Compound Library Inhibitor Library Anti-Breast Cancer Compound Library Kinase Inhibitor Library Bioactive Compound Library PI3K-AKT-mTOR Compound Library

Related Products

Related compounds with same targets

GSK-F1 KDU691 BQR-695 GSK-A1 AZ044 GSK-F1 T-00127_HEV1 BF738735

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

UCB9608 1616413-96-7 PI3K/Akt/mTOR信号通路 PI4K Phosphatidylinositol 4 kinases UCB-9608 Inhibitor UCB 9608 PI4 kinases inhibit inhibitor

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