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Search Results for " parkinson "

20

Compounds

Cat No. Product Name Synonyms Targets
TC0039 Vasicinone Others
Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiprolifer...
T7831 Nitecapone Others , Transferase
Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver)
T7626 Budipine Others
Budipine is a low affinity, N-methyl-D-aspartate receptor antagonist,is an antiparkinsonian agent.
T9346 CVN424 GPR
CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.
T8849 PF-9601N MAO
PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.
T9694 Emraclidine CVL-231 AChR
Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator and can be used in neurological diseases studies.
T8975 PSB-SB-487 Cannabinoid Receptor
PSB-SB-487 is antagonist of GPR55.
T9228 Propionylpromazine hydrochloride Propiopromazine hydrochloride Dopamine Receptor
Propionylpromazine hydrochloride (Propiopromazine hydrochloride) is a dopamine receptor D2 (DRD2) antagonist.
T8869 B355252 Others
B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.
T0848 L-DOPA Levodopa,3,4-Dihydroxyphenylalanine Dopamine Receptor , Endogenous Metabolite
L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brai...
T22103 ML-193 CID 1261822 Cannabinoid Receptor
ML-193 (CID 1261822) is a potent and selective GPR55 antagonist( IC50 : 221 nM). It shows more than 27-fold selectivity for GPR55 over GPR35, CB1 and CB2, and can improve the motor and the sensorimotor deficits of Parkin...
T37792 A2A receptor antagonist 1 CPI-444 analog,A2A receptor antagonist 1 Adenosine Receptor
A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Kis of 4 and 264 nM, respectively.
T14782 Brilaroxazine RP5063 Dopamine Receptor , 5-HT Receptor
Brilaroxazine (RP5063) is a potent multimodal dopamine/5-HT modulator. Brilaroxazine is a partial agonist of dopamine D2, D3, and D4 receptors, 5-HT1A (Ki =1.5 nM) and 5-HT2A (Ki = 2.5 nM), and has antagonist activity 5-...
T6234 Ambroxol hydrochloride Mucosolvan,Mucoangin,Ambroxol HCl Sodium Channel , Autophagy
Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.
T0920 Ambroxol Ambroxolum,NA-872 P450 , Autophagy
Ambroxol (NA-872) is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a muco...
TN2011 Ombuoside Ombuin-3beta-rutinoside Antibacterial
Ombuoside (Ombuin-3beta-rutinoside) has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays.Ombuoside is a glycoside ombuoside isolated from Gynostemma penta...
T7002 Trihexyphenidyl hydrochloride Triesifenidile,Benzhexol hydrochloride,Tremin,Artane hydrochloride AChR
Trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is an antiparkinsonian agent of the antimuscarinic class.
T4024 Norharmane 2-Azacarbazole,2,9-Diazafluorene,β-Carboline DNA , Endogenous Metabolite , Monoamine Oxidase
Norharmane (β-Carboline) is a natural β-carboline first isolated from plants of the Zygophyllaceae family.
T5678 Lazabemide hydrochloride N-(2-Aminoethyl)-5-chlor-2-pyridincarbox MAO , Monoamine Oxidase
Lazabemide hydrochloride (N-(2-Aminoethyl)-5-chlor-2-pyridincarbox) is a reversible and selective mao-b inhibitor(Ki:7.9nM).
T24047 Etilevodopa hydrochloride Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester Others , Dopamine Receptor , Drug Metabolite
Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration.

Compounds

Vasicinone
TC0039
Synonym:
Target: Others
Nitecapone
T7831
Synonym:
Target: Others, Transferase
Budipine
T7626
Synonym:
Target: Others
CVN424
T9346
Synonym:
Target: GPR
PF-9601N
T8849
Synonym:
Target: MAO
Emraclidine
T9694
Synonym: CVL-231
Target: AChR
PSB-SB-487
T8975
Synonym:
Target: Cannabinoid Receptor
Propionylpromazine hydrochloride
T9228
Synonym: Propiopromazine hydrochloride
Target: Dopamine Receptor
B355252
T8869
Synonym:
Target: Others
L-DOPA
T0848
Synonym: Levodopa,3,4-Dihydroxyphenylalanine
Target: Dopamine Receptor, Endogenous Metabolite
ML-193
T22103
Synonym: CID 1261822
Target: Cannabinoid Receptor
A2A receptor antagonist 1
T37792
Synonym: CPI-444 analog,A2A receptor antagonist 1
Target: Adenosine Receptor
Brilaroxazine
T14782
Synonym: RP5063
Target: Dopamine Receptor, 5-HT Receptor
Ambroxol hydrochloride
T6234
Synonym: Mucosolvan,Mucoangin,Ambroxol HCl
Target: Sodium Channel, Autophagy
Ambroxol
T0920
Synonym: Ambroxolum,NA-872
Target: P450, Autophagy
Ombuoside
TN2011
Synonym: Ombuin-3beta-rutinoside
Target: Antibacterial
Trihexyphenidyl hydrochloride
T7002
Synonym: Triesifenidile,Benzhexol hydrochloride,Tremin,Artane hydrochloride
Target: AChR
Norharmane
T4024
Synonym: 2-Azacarbazole,2,9-Diazafluorene,β-Carboline
Target: DNA, Endogenous Metabolite, Monoamine Oxidase
Lazabemide hydrochloride
T5678
Synonym: N-(2-Aminoethyl)-5-chlor-2-pyridincarbox
Target: MAO, Monoamine Oxidase
Etilevodopa hydrochloride
T24047
Synonym: Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester
Target: Others, Dopamine Receptor, Drug Metabolite
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TargetMol