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Cat No. | Product Name | Synonyms | Targets |
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T16504 | PF-4693627 | Prostaglandin Receptor | |
PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM). It is used for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA). | |||
T36830 | 9-Nitrooleate | ||
Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate , cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules. LNO2 isomers serve as p... | |||
T72828 | α-Amylase-IN-2 | ||
α-Glucosidase-IN-3, an oxime ester derivative of oleanolic acid (OA), exhibits inhibitory activity against α-glucosidase (IC50 = 1.28 µM) and α-amylase (IC50 = 3.8 µM). | |||
T72296 | Cathepsin K inhibitor 3 | ||
Cathepsin K Inhibitor 3, exhibiting an IC50 value of 0.5 nM, is a highly selective inhibitor of cathepsin K, featuring a favorable pharmacokinetic profile. It holds potential for use in studies of osteoarthritis (OA). | |||
T16291 | NF157 | COX | |
NF157 significantly decreases the expression of metalloproteinase (MMP)-3, MMP-13, which can be used in the treatment of osteoarthritis (OA). NF157 is a highly selective nanomolar P2Y11 antagonist (pKi: 7.35). The IC50s ... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN3862 | Dihydroprehelminthosporol | Others | |
Dihydroprehelminthosporol is a strongly phytotoxic metabolite, it exhibits cytotoxicity towards two human cancer cell lines, A549 and SK-OA-3. | |||
T78468 | Yohimbic acid hydrate | ||
Yohimbic acid hydrate, an amphoteric demethylated derivative of Yohimbine, exhibits vasodilatory properties and is utilized in osteoarthritis (OA) research [1] [2] [3]. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04935 | CD47 Protein, Human, Recombinant (aa 1-139, His) | Human | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-05191 | CD47 Protein, Human, Recombinant, Biotinylated | Human | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-04683 | CD47 Protein, Human, Recombinant | Human | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-03883 | CD47 Protein, Human, Recombinant (hFc) | Human | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-06367 | CD47 Protein, Human, Recombinant (aa 19-139, His) | Human | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPK-00644 | CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) | Cynomolgus,Rhesus macaque | HEK293 |
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with... | |||
TMPY-03847 | FRZB Protein, Human, Recombinant (His) | Human | HEK293 |
FRZB also known as sFRP-3, is a secreted protein containing a domain similar to the putative Wnt-binding region of the frizzled family of transmembrane receptors. FRZB is widely expressed in adult mammalian tissues. In t... | |||
TMPY-00433 | CXCL1 Protein, Mouse, Recombinant | Mouse | E. coli |
The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu... | |||
TMPY-00008 | CXCL1 Protein, Rat, Recombinant | Rat | E. coli |
The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu... | |||
TMPY-00357 | HNT/NTM Protein, Human, Recombinant (His) | Human | HEK293 |
NTM (Neurotrimin) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylph... | |||
TMPY-06986 | FGF-8b Protein, Human, Recombinant | Human | E. coli |
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment... | |||
TMPY-04142 | RANK/TNFRSF11A Protein, Human, Recombinant (hFc) | Human | HEK293 |
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i... | |||
TMPY-05748 | CD45 Protein, Human, Recombinant (aa 26-577, His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-00132 | Mesothelin Protein, Human, Recombinant | Human | HEK293 |
The megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glyc... | |||
TMPY-03763 | Neuropilin-2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac... | |||
TMPY-00892 | Neuropilin-2 Protein, Human, Recombinant (His) | Human | HEK293 |
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac... | |||
TMPY-01020 | Periostin/OSF-2 Protein, Human, Recombinant (His) | Human | HEK293 |
Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ... | |||
TMPY-01897 | PRSS3 Protein, Human, Recombinant (His) | Human | HEK293 |
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on... | |||
TMPY-02868 | CXCL1 Protein, Human, Recombinant | Human | E. coli |
The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu... | |||
TMPY-02026 | CXCL1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu... | |||
TMPY-02180 | CXCL1 Protein, Human, Recombinant (His & NusA) | Human | E. coli |
The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu... | |||
TMPY-04298 | CDCP1 Protein, Human, Recombinant (His) | Human | HEK293 |
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ... | |||
TMPY-00480 | NCAM1 Protein, Human, Recombinant (His) | Human | HEK293 |
NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobuli... | |||
TMPY-01180 | CD86 Protein, Human, Recombinant (His) | Human | HEK293 |
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co... | |||
TMPJ-01099 | IL-15RA Protein, Human, Recombinant (hFc, Human Cells) | Human | Human Cells |
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bi... | |||
TMPY-00072 | GITR/TNFRSF18 Protein, Human, Recombinant (His) | Human | HEK293 |
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)... | |||
TMPY-06411 | GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)... | |||
TMPY-05590 | NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobuli... | |||
TMPY-04273 | FGFR2 Protein, Human, Recombinant (aa 1-378, His) | Human | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro... | |||
TMPY-05383 | NKp30/NCR3 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Natural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and... | |||
TMPY-03969 | SUSD4 Protein, Human, Recombinant (mFc) | Human | HEK293 |
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and ... | |||
TMPY-04157 | RANK/TNFRSF11A Protein, Human, Recombinant (His) | Human | HEK293 |
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i... | |||
TMPY-01268 | SMYD3 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger... | |||
TMPY-01656 | VEGF183 Protein, Human, Recombinant | Human | Baculovirus-Insect Cells |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPJ-00390 | FGFR2IIIb Protein, Human, Recombinant (hFc) | Human | Human Cells |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro... | |||
TMPK-00447 | CD45 Protein, Human, Recombinant (aa 26-577, hFc) | Human | HEK293 |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com... | |||
TMPK-00399 | FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated | Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c... | |||
TMPJ-00899 | HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) | Human | Human Cells |
Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belon... | |||
TMPY-04386 | EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) | Human | Baculovirus-Insect Cells |
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5... | |||
TMPY-00276 | PLGF/PGF Protein, Human, Recombinant (mFc) | Human | HEK293 |
PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 with mFc tag. The predicted molecular weight is 43.7 kDa. Accession number: P49763-3 | |||
TMPY-03960 | COL9A1 Protein, Human, Recombinant (His) | Human | HEK293 |
COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 34.2 kDa. Accession number: P20849-3 | |||
TMPY-05514 | RANK/TNFRSF11A Protein, Human, Recombinant (mFc) | Human | HEK293 |
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i... | |||
TMPY-03435 | NCKIPSD Protein, Human, Recombinant (GST) | Human | E. coli |
NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction and may function in the maintenance of sarcomeres and the assembly of myofibrils into sarcomeres. NCKIPSD also plays an importa... | |||
TMPY-05246 | CD86 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co... | |||
TMPY-03621 | EphB2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5... | |||
TMPY-02691 | IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) | Human | HEK293 |
IL17RC (Interleukin 17 Receptor C) is a Protein Coding gene. This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). IL17RC is widely expressed in the pr... | |||
TMPK-00398 | FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) | Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c... | |||
TMPJ-00054 | PLGF-2 Protein, Human, Recombinant (His) | Human | Human Cells |
Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. Alternate splicing results in at least three human mature PlGF f... | |||
TMPJ-01288 | KLF6 Protein, Human, Recombinant | Human | E. coli |
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by ... | |||
TMPJ-00391 | FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) | Human | Human Cells |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro... | |||
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