Search Result

Search Results for " ntri "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T8515	Osoresnontrine	BI-409306	PDE
	Osoresnontrine is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be used in the research of memory.		PDE
T3266	Lumefantrine	Benflumetol,dl-Benflumelol	Others , Parasite , Autophagy
	Lumefantrine (dl-Benflumelol) is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy exerts its effects again...		Others , Parasite , Autophagy
T8333	Aurintricarboxylic acid	ATA,NSC-4056,NSC4056,NSC 4056	Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase
	Aurintricarboxylic acid (NSC-4056) is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme.		Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase
T61833	Tovinontrine	IMR-687	PDE
	Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment. It exhibits high efficacy, with IC 50 values of 8.19 nM and 9.99 nM fo...		PDE
T11991	Mefentrifluconazole		P450 , Antifungal
	Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase (IC50=0.92 μM). Mefentrifluconazole is a novel azole derivative and ...		P450 , Antifungal
T16809	Rupintrivir	AG-7088,AG7088,Rupintrivirvr	Virus Protease , Antiviral
	Rupintrivirvr (AG7088) is a selective rhinovirus (HRV) 3C cysteine protease mimetic peptide inhibitor with antiviral and immunomodulatory activities.Rupintrivirvr inhibits the replication of EV71 and EV-D68, and may be u...		Virus Protease , Antiviral
T25376	Ensifentrine	Ensifentrina,Ensifentrinum	PDE
	Ensifentrine (Ensifentrinum) is a PDE3/4 inhibitor, although its affinity for PDE3(IC50: 0.4 nM) is 3,440 times higher than that for PDE4(IC50: 1479 nM), that is under clinical development for the treatment of asthma and...		PDE
T14927	Centrinone	LCR-263	PLK , Aurora Kinase
	Centrinone (LCR-263) (LCR-263) is a reversible inhibitor of polo-like kinase 4 (PLK4; Ki:0.16 nM).		PLK , Aurora Kinase
T71691	Pumafentrine	BY 343	PDE
	Pumafentrine（BY 343） is a dual PDE3/PDE4 inhibitor that reduces clinical scores and TNF expression in experimental colitis in mice.		PDE
TN6963	Hentriacontane		NF-κB
	Hentriacontane is a natural product.		NF-κB
T31745	Fantridone HCl	Fantridone hydrochloride,AGN-616,AGN616,AGN 616
	Fantridone HCl is a biochemical.
T10999	Desbutyl Lumefantrine	Desbutyl-benflumetol	Others
	Desbutyl Lumefantrine is a metabolite of lumefantrine with antimalarial activity.		Others
T69075	Dicentrine HCl
	Dicentrine HCl is the salt form of Dicentrine, an alpha 1-adrenoceptor antagonist effective against human hyperplastic prostates.
T25485	Halofantrine, (-)-	L-WR-171669
	Halofantrine, (-)- is an antimalarial agent.
T26565	Adentri	BG-9719,BG9719,BG 9719,CVT124,CVT-124,CVT 124
	Adentri is a novel antagonist of adenosine A1 receptor with unique diuretic activity.
T61770	(R)-Irsenontrine
	(R)-Irsenontrine ((R)-E2027), the R-enantiomer of Irsenontrine, serves as a potent inhibitor of phosphodiesterase 9 (PDE9) with an inhibition concentration (IC50) of 0.041 μM, primarily utilized in the research of neurol...
T63393	Halofantrine
	Halofantrine is an antimalarial active substance that is highly lipophilic and has a blocking effect on HERG potassium channels against the Chloroquine resistant Plasmodium falciparum.
T33922	Pentrinitrol	W-2197,W 2197,W2197
	Pentrinitrol is a biochemical.
T35062	Vintriptol	Vintriptolum
	Vintriptol is a biochemical.
T26767	Benafentrine dimaleate	Benafentrine
	Benafentrine dimaleate is a platelet activating factor receptor (PAFR) antagonists and phosphodiesterase (PDE) 3/4 inhibitors.
T19275	Desbutyl Lumefantrine D9	Desbutyl-benflumetol D9	Others
	Desbutyl Lumefantrine D9, a deuterium-labeled metabolite of Lumefantrine, exhibits the incorporation of deuterium atoms.		Others
T29314	Lumefantrine Impurity A	2-(Dibutylamino)-2-(2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol, (RS, Z)-
	2-(Dibutylamino)-2-(2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol, (RS, Z)- is a bioactive chemical.
T11891	Lumefantrine-d18	Benflumetol D18,Lumefantrine D18	Others
	Lumefantrine D18 is an antimalarial drug, and is the deuterium labeled Lumefantrine.		Others
T14926	Centrinone-B	LCR-323	Aurora Kinase
	Centrinone-B (LCR-323) is a potent and highly selective inhibitor of PLK4 (Ki: 0.59 nM).		Aurora Kinase
T25101	Antrimycin	Antrimycin A,Cirratiomycin B
	Antrimycin is an antibiotic.
T39586	Cantrixil	TRX-E-002-1
	Cantrixil (TRX-E-002-1) is a second-generation super-benzopyran (SBP) compound, derived from TRX-E-002. It elicits an increase in phosphorylated c-Jun levels, leading to caspase-mediated apoptosis in ovarian cancer cells...
T38899	Irsenontrine	E2027,Irsenontrine
	Irsenontrine (E2027) is a selective and orally active inhibitor of phosphodiesterase 9 (PDE9), primarily used for researching neurological diseases.
T39108	Irsenontrine maleate	E2027 maleate
	Irsenontrine (E2027) maleate is a selective and orally active inhibitor of phosphodiesterase 9 (PDE9). It can be utilized in the study of neurological diseases.
T33279	Meliantriol
	Meliantriol is an active compound in Azadirachta indica (Neem). It can bind to PBP2A and PVL toxin with the binding energies of -6.02 kcal/mol and -8.94 kcal/mol, respectively.
T33603	Nb-enantride
	Nb-enantride is a novel chiral trialkylborohydride for the asymmetric reduction of ketones.
T15460	Halofantrine hydrochloride	WR-171669,SKF-102886	Others
	Halofantrine hydrochloride is a blocker of delayed rectifier potassium current. Halofantrine hydrochloride also via the inhibition of the human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial agent.		Others
T69491	(E/Z)-Ensifentrine
	(E/Z)-Ensifentrine is a potent and selective PDE3/4 inhibitor. (E/Z)-Ensifentrine acts as a long-acting inhibitor of the phosphodiesterase enzymes PDE-3 and PDE-4, producing both bronchodilator and antiinflammatory effec...

Compounds

Synonym: Benflumetol,dl-Benflumelol

Target: Others, Parasite, Autophagy

Aurintricarboxylic acid

T8333

Synonym: ATA,NSC-4056,NSC4056,NSC 4056

Target: Apoptosis, P2X Receptor, Influenza Virus, Topoisomerase

Target: P450, Antifungal

Rupintrivir

T16809

Synonym: AG-7088,AG7088,Rupintrivirvr

Target: Virus Protease, Antiviral

Ensifentrine

T25376

Synonym: Ensifentrina,Ensifentrinum

Target: PLK, Aurora Kinase

Synonym: Fantridone hydrochloride,AGN-616,AGN616,AGN 616

Target:

Desbutyl Lumefantrine

T10999

Synonym: Desbutyl-benflumetol

Synonym: BG-9719,BG9719,BG 9719,CVT124,CVT-124,CVT 124

Synonym: W-2197,W 2197,W2197

Target:

Vintriptol

T35062

Synonym: Vintriptolum

Target:

Benafentrine dimaleate

T26767

Synonym: Benafentrine

Target:

Desbutyl Lumefantrine D9

T19275

Synonym: Desbutyl-benflumetol D9

Target: Others

Lumefantrine Impurity A

T29314

Synonym: 2-(Dibutylamino)-2-(2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol, (RS, Z)-

Target:

Lumefantrine-d18

T11891

Synonym: Benflumetol D18,Lumefantrine D18

Target: Aurora Kinase

Antrimycin

T25101

Synonym: Antrimycin A,Cirratiomycin B

Synonym: E2027,Irsenontrine

Target:

Irsenontrine maleate

T39108

Synonym: E2027 maleate

Halofantrine hydrochloride

T15460

Synonym: WR-171669,SKF-102886

Cat No.	Product Name	Synonyms	Targets
T20225	Dicentrine, (-)-	L-Dicentrine,NSC 251699,NSC251699,NSC-251699	Others
	Dicentrine, (-)- (NSC-251699) is an aporphinic alkaloid found in several plant species, which showed significant antinociceptive activity in an acute model of visceral pain in mice.		Others
TN5690	Carpinontriol A
	Carpinontriol A is a natural product for research related to life sciences. The catalog number is TN5690 and the CAS number is 473451-72-8.
TN3336	Acantrifoic acid A		Others
	Acantrifoic acid A is a natural product from Acanthopanax trifoliatus.		Others
TN3547	Bullatantriol		Antifection
	Bullatantriol has a stimulative effect on significantly proliferation and differentiation of culture osteoblasts. It may have weak antibacterial activities.		Antifection
TN3603	Carpinontriol B		IL Receptor , Antifection
	Carpinontriol B has antimicrobial activity, it at 40 ug/disk caused the formation of zones of inhibition. It also has anti-inflammatory activity, it shows considerable inhibition on the production of nitric oxide and red...		IL Receptor , Antifection
TN1577	Dicentrine		Others
	Dicentrine, a selective α±(1)-adrenoceptor antagonist with potent antiarrhythmic and antihypertensive activities, it also has antinociception in different models of chemical pain.		Others
T11365	Ganodermanontriol		Others
	Ganodermanontriol, a sterol derived from Ganoderma lucidum, showcases hepatoprotective activity and possesses anti-inflammatory properties in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the upregulatio...		Others
TN3337	Acantrifoside E		Others
	Acantrifoside E is a natural product of Ferula, Apiaceae. The catalog number is TN3337 and the CAS number is 645414-25-1. Acantrifoside E can be used as a reference standard.		Others
TN1559	Dehydrodicentrine		AChR
	Dehydrodicentrine showed strong acetylcholinesterase (AChE) inhibitory effects with the IC50 value of 2.98 μM.		AChR

Natural Products

Dicentrine, (-)-

T20225

Synonym: L-Dicentrine,NSC 251699,NSC251699,NSC-251699

Target: IL Receptor, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00357	HNT/NTM Protein, Human, Recombinant (His)	Human	HEK293
	NTM (Neurotrimin) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylph...
TMPY-00355	HNT/NTM Protein, Human, Recombinant (hFc)	Human	HEK293
	NTM (Neurotrimin) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylph...
TMPY-03221	Intrinsic Factor Protein, Human, Recombinant (His)	Human	HEK293
	Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the ...
TMPY-00530	Centrin 2 Protein, Human, Recombinant (His)	Human	HEK293
	Centrin 2 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 21.2 kDa. Accession number: P41208
TMPH-03145	Thanatin Protein, Podisus maculiventris, Recombinant (His & KSI)	Podisus maculiventris	E. coli
	Insect defense peptide with a broad spectrum of activity against Gram-positive and Gram-negative bacteria and fungi. No activity against S.aureus. Stops respiration in bacteria but does not permeabilize their inner membr...