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Hentriacontane

Catalog No. TN6963   CAS 630-04-6

Hentriacontane is a natural product with various pharmacological effects including anti-inflammatory, antitumor, and antimicrobial activities.

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Hentriacontane Chemical Structure
Hentriacontane, CAS 630-04-6
Pack Size Availability Price/USD Quantity
5 mg In stock $ 50.00
10 mg In stock $ 75.00
25 mg In stock $ 128.00
50 mg In stock $ 192.00
100 mg In stock $ 287.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Hentriacontane is a natural product with various pharmacological effects including anti-inflammatory, antitumor, and antimicrobial activities.
In vitro Hentriacontane(10μM, 5μM and 1μM) significantly reduced all the parameters of inflammation in the experiments under study at all the concentrations. Suppressive potential of hentriacontane on NO, PGE2, LTB4 and on LPS induced translocation of NF-κB in RAW 264.7 cells was studied[2].
In vivo Hentriacontane(5mg/kg, 2mg/kg and 1mg/kg) also reduced all the parameters of inflammation in the experiments under study at all the concentrations. Cytokine inhibition of both pro-inflammatory (TNF-α, IL-6, MCP-1 and IL-1β) and anti-inflammatory (IL-10) cytokines was studied in Balb/c mice[2].
Molecular Weight 436.84
Formula C31H64
CAS No. 630-04-6

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 1 mg/mL, Sonication is recommended.

DMSO: Insoluble

TargetMolReferences and Literature

1. Kim SJ, et al. Antiinflammatory effect of Oldenlandia diffusa and its constituent, hentriacontane, through suppression of caspase-1 activation in mouse peritoneal macrophages. Phytother Res. 2011 Oct;25(10):1537-46. 2. Khajuria V, et al. Anti-inflammatory potential of hentriacontane in LPS stimulated RAW 264.7 cells and mice model. Biomed Pharmacother. 2017 Aug;92:175-186.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Active Compound Library Tobacco Monomer Library Traditional Chinese Medicine Monomer Library Microbial Natural Product Library Miao medicine Compound Library Anti-Prostate Cancer Compound Library Human Metabolite Library Anti-Tumor Natural Product Library Anti-Liver Cancer Compound Library Anti-Pancreatic Cancer Compound Library

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Keywords

Hentriacontane 630-04-6 NF-Κb NF-κB inhibitor inhibit

 

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