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Search Results for " nf-kb-in-2 "

8

Compounds

Cat No.	Product Name	Synonyms	Targets
T60357	NF-κB-IN-2	JEUD-38
	NF-κB-IN-2 inhibits canonical NF-κB signaling induced by TNF-α in PC-3 cells.
T8951	JTP 0819958 - HOIPIN-1		IκB/IKK
	JTP-0819958 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM[1]. JTP-0819958 suppress LUBAC-mediated NF-kB activation in vitro[2].		IκB/IKK
T5727	CAFESTOL		ERK , NF-κB , COX , PGE Synthase
	CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production...		ERK , NF-κB , COX , PGE Synthase
T0005	Aspirin	Acetylsalicylate,Acetylsalicylic Acid,ASA	Mitophagy , Virus Protease , COX , Autophagy
	Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel...		Mitophagy , Virus Protease , COX , Autophagy
T3826	Polygalasaponin F		NF-κB , TLR , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...		NF-κB , TLR , Akt , PI3K
T5S0761	Nitidine chloride		Apoptosis , ERK , FAK , p38 MAPK , NF-κB , Topoisomerase , STAT , Parasite
	1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id...
T4S0969	Obtusifolin		Antioxidant , NF-κB
	1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be...		Antioxidant , NF-κB
T71285	Metaxalone-d6
	Metaxalone-d6 is intended for use as an internal standard for the quantification of metaxalone by GC-or LC-MS. Metaxalone is a skeletal muscle relaxant. It inhibits the proliferation of, and induces apoptosis in, RAW 264...

Compounds

Synonym: JEUD-38

JTP 0819958 - HOIPIN-1

Target: IκB/IKK

Target: ERK, NF-κB, COX, PGE Synthase

Synonym: Acetylsalicylate,Acetylsalicylic Acid,ASA

Target: Mitophagy, Virus Protease, COX, Autophagy

Polygalasaponin F

Target: NF-κB, TLR, Akt, PI3K

Nitidine chloride

Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite

Target: Antioxidant, NF-κB

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