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Search Results for " melatonin "

20

Compounds

Cat No. Product Name Synonyms Targets
T1659 Melatonin Melatonine,N-Acetyl-5-methoxytryptamine CaMK , Apoptosis , Mitophagy , Estrogen/progestogen Receptor , Melatonin Receptor , Glutathione Peroxidase , Endogenous Metabolite , ROR , Autophagy
Melatonin (Melatonine) is a biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin...
T11995 Melatonin-d4 N-Acetyl-5-methoxytryptamine D5,Melatonin D5 Others
Melatonin D5, a deuterium-labeled version of melatonin, is a hormone produced by the pineal gland, known for its role as a selective ATF-6 inhibitor that promotes apoptosis in human hepatoma cells via COX-2 downregulatio...
T64745 Melatonin Biotin
Melatonin Biotin is a useful organic compound for research related to life sciences and the catalog number is T64745.
T60490 Melatonin receptor agonist 1
Melatonin receptor agonist 1 (compound 20c) is a potent agonist of melatonin receptor (MT) with Ki values of 108 nM for MT2 and 1140 nM for MT 1 [1].
T14042 4-P-PDOT 4-phenyl-2- propionamidotetralin Melatonin Receptor , MT Receptor
4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.
T9193 ACH-000143 Melatonin Receptor , MT Receptor
ACH-000143 have been identified as a novel agonist of the melatonin receptors MT1 and MT2.
T8600 N-ACETYLTRYPTAMINE Melatonin Receptor
N-ACETYLTRYPTAMINE is a partial agonist for melatonin receptors in the retina. Also used for determination of serotonin N-acetyl transferase.
T1463 Ramelteon TAK-375 Melatonin Receptor , MT Receptor
Ramelteon (TAK-375) is a Melatonin Receptor Agonist. The mechanism of action of ramelteon is as a Melatonin Receptor Agonist.
T15795 Luzindole N-0774 Melatonin Receptor , MT Receptor
Luzindole (N-0774) is a selective melatonin receptor antagonist. Luzindole inhibits experimental autoimmune encephalomyelitis and exerts antidepressant-like activity. Luzindole preferentially targets MT2 (Mel1b) over MT1...
T3495 Tasimelteon VEC-162,BMS-214778 Melatonin Receptor , MT Receptor
Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.
T1445 Agomelatine Thymanax,S-20098,Valdoxan Melatonin Receptor , 5-HT Receptor
Agomelatine (Valdoxan) is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression.
T16834 S26131 N-[2-[7-[3-[8-(2-acetamidoethyl)naphthalen-2-yl]oxypropoxy]naphthalen-1-yl]ethyl]acetamide MT Receptor
S26131 (N-[2-[7-[3-[8-(2-acetamidoethyl)naphthalen-2-yl]oxypropoxy]naphthalen-1-yl]ethyl]acetamide) behaves as an antagonist on MT1 and MT2 receptors with Ki of 0.5 and 112 nM respectively.
T22530 6-Chloromelatonin Melatonin Receptor , Dopamine Receptor
6-Chloromelatonin is a potent melatonin receptor agonist, a 5-methoxyindole compound that competes for the same presynaptic melatonin receptor sites in the rabbit retina and inhibits the calcium-dependent release of [3H]...
T10073 2-Iodomelatonin Melatonin Receptor
2-Iodomelatonin is a potent agonist of melatonin receptor 1 (MT1) with a Ki value of 28 pM, it is more 5-fold selective for MT1 over MT2. 2-iodomelatonin can be used to identify, characterize and localize melatonin bind...
T13520 6-Hydroxymelatonin Others
6-Hydroxymelatonin is a primary metabolic of Melatonin, which is metabolized by CYP 1A2.
T13513 5-Methoxyindole-3-acetic acid Methoxyindoleacetic acid,5-Methoxyindoleacetic acid Endogenous Metabolite
5-Methoxyindole-3-acetic acid (5-Methoxyindoleacetic acid) is a metabolite of Melatonin and is isolated from pineal tissue.
T1354 N-Acetyl-5-hydroxytryptamine Normelatonin,O-Demethylmelatonin,N-Acetylserotonin Trk receptor , Endogenous Metabolite
N-Acetyl-5-hydroxytryptamine (O-Demethylmelatonin) , also known as Normelatonin, is the immediate precursor of melatonin. It is produced from serotonin by the enzyme aralkylamine N-acetyltransferase and is converted to m...
T10929L D-3263 hydrochloride EC D-3263 HCl,D3263 HCl salt TRP/TRPV Channel
D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.
T41345 AFMK Formyl-N-acetyl-5-methoxykynurenamine,Acetyl-N-formyl-5-methoxykynurenamine Apoptosis , Free radical scavengers , Antioxidant , Endogenous Metabolite
AFMK (Formyl-N-acetyl-5-methoxykynurenamine) is an active metabolite of Melatonin with antioxidant and free radical scavenging activity. AFMK is a modulator of apoptosis and improves the anti-tumor effect of Gemcitabine ...
T8181 Poricoic acid A Poricoic acid A(F) Others
Poricoic acid A (Poricoic acid A(F)) is a natural product with antitumor activity. It also enhances melatonin inhibition of AKI-to-CKD transition by regulating the Gas6/AxlNFκB/Nrf2 axis.

Compounds

Melatonin
T1659
Synonym: Melatonine,N-Acetyl-5-methoxytryptamine
Target: CaMK, Apoptosis, Mitophagy, Estrogen/progestogen Receptor, Melatonin Receptor, Glutathione Peroxidase, Endogenous Metabolite, ROR, Autophagy
Melatonin-d4
T11995
Synonym: N-Acetyl-5-methoxytryptamine D5,Melatonin D5
Target: Others
Melatonin Biotin
T64745
Synonym:
Target:
Melatonin receptor agonist 1
T60490
Synonym:
Target:
4-P-PDOT
T14042
Synonym: 4-phenyl-2- propionamidotetralin
Target: Melatonin Receptor, MT Receptor
ACH-000143
T9193
Synonym:
Target: Melatonin Receptor, MT Receptor
N-ACETYLTRYPTAMINE
T8600
Synonym:
Target: Melatonin Receptor
Ramelteon
T1463
Synonym: TAK-375
Target: Melatonin Receptor, MT Receptor
Luzindole
T15795
Synonym: N-0774
Target: Melatonin Receptor, MT Receptor
Tasimelteon
T3495
Synonym: VEC-162,BMS-214778
Target: Melatonin Receptor, MT Receptor
Agomelatine
T1445
Synonym: Thymanax,S-20098,Valdoxan
Target: Melatonin Receptor, 5-HT Receptor
S26131
T16834
Synonym: N-[2-[7-[3-[8-(2-acetamidoethyl)naphthalen-2-yl]oxypropoxy]naphthalen-1-yl]ethyl]acetamide
Target: MT Receptor
6-Chloromelatonin
T22530
Synonym:
Target: Melatonin Receptor, Dopamine Receptor
2-Iodomelatonin
T10073
Synonym:
Target: Melatonin Receptor
6-Hydroxymelatonin
T13520
Synonym:
Target: Others
5-Methoxyindole-3-acetic acid
T13513
Synonym: Methoxyindoleacetic acid,5-Methoxyindoleacetic acid
Target: Endogenous Metabolite
N-Acetyl-5-hydroxytryptamine
T1354
Synonym: Normelatonin,O-Demethylmelatonin,N-Acetylserotonin
Target: Trk receptor, Endogenous Metabolite
D-3263 hydrochloride
T10929L
Synonym: EC D-3263 HCl,D3263 HCl salt
Target: TRP/TRPV Channel
AFMK
T41345
Synonym: Formyl-N-acetyl-5-methoxykynurenamine,Acetyl-N-formyl-5-methoxykynurenamine
Target: Apoptosis, Free radical scavengers, Antioxidant, Endogenous Metabolite
Poricoic acid A
T8181
Synonym: Poricoic acid A(F)
Target: Others
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TargetMol