Powder: -20°C for 3 years | In solvent: -80°C for 1 year
D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 72.00 | |
5 mg | In stock | $ 113.00 | |
10 mg | In stock | $ 178.00 | |
25 mg | In stock | $ 333.00 | |
50 mg | In stock | $ 559.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 97.00 |
Description | D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist. |
In vitro | D-3263 hydrochloride binds and activates TRPM8, which may lead to increased entry of calcium and sodium; destruction of calcium and sodium homeostasis; induction of cell death in tumor cells expressing TRPM8. D-3263 hydrochloride may reduce the level of dihydrotestosterone (DHT), which may contribute to its inhibitory effect on prostate cancer and BPH[1]. |
Synonyms | EC D-3263 HCl, D3263 HCl salt |
Molecular Weight | 409.95 |
Formula | C21H32ClN3O3 |
CAS No. | 1008763-54-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 35 mg/mL (85.4 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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D-3263 hydrochloride 1008763-54-9 Membrane transporter/Ion channel TRP/TRPV Channel EC D-3263 HCl D3263 HCl salt D3263 Hydrochloride D-3263 Hydrochloride D3263 HCl D 3263 Hydrochloride inhibitor inhibit