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Search Result

Search Results for " mav "

Targets

5-HT Receptor

19

Compounds

8

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T2076 Pimavanserin ACP-103 5-HT Receptor
Pimavanserin (ACP-103)(ACP-103) is an effective and specific 5-HT2A receptor inverse agonist (mean pIC50: 8.7, in the cell-based functional assay). Pimavanserin is an atypical antipsychotic used in the treatment of hallu...
T37979 N-Desmethyl Pimavanserin AC-279 5-HT Receptor
N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin, a 5-HT2A receptor inverse agonist, which is used in the treatment of sleep disorders such as insomnia.
TQ0174 Mavorixafor AMD-070 CXCR
Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC...
T12527L Mavodelpar free acid hydrochloride Mavodelpar free acid hydrochloride(942594-93-6 Free base),Pparδ agonist HCl,HPP593 free acid HCl,REN001 free acid HCl PPAR
Mavodelpar free acid hydrochloride (Pparδ agonist HCl) is a potent PPARδ agonist.
T21322 Mavelertinib PF 06747775,PFE-X775,PF-06747775,PF-7775,PF 6747775,PF6747775 EGFR
Mavelertinib (PF-06747775) is an orally available, selective and potent EGFR tyrosine kinase (EGFR TKI) inhibitor with inhibitory effects on T790M/L858R and T790M/Del, and can be used in the study of oncology and respira...
T76690 Mavrilimumab CAM 3001 Virus Protease , CSF-1R
Mavrilimumab (CAM 3001) is a monoclonal antibody with antiviral activity that has an affinity for the α subunit of the granulocytic-macrophage colony-stimulating factor (GM-CSF) receptor and blocks downstream intracellul...
T7670 Mavacoxib COX
Mavacoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) ,with Anti-Tumour activity.
T6919 Omaveloxolone RTA-408 Apoptosis , Others , Nrf2 , STING
Omaveloxolone (RTA-408) (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.
T6946 Pimavanserin tartrate ACP-103,ACP-103 tartrate,Nuplazid,Pimavanserin 5-HT Receptor
Pimavanserin tartrate (Nuplazid) is an effective and specific serotonin 5-HT2A inverse agonist (pIC50: 8.73), used in the therapy of psychosis associated with Parkinson's disease.
T16014 Mavatrep JNJ-39439335 TRP/TRPV Channel
Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can be used for studies about inflammatory pain.
T7134 Mavacamten MYK-461,SAR439152 Myosin
Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)
T10296 Mavorixafor trihydrochloride AMD-070 trihydrochloride HIV Protease
Mavorixafor trihydrochloride is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs (I...
T73088 Mavodelpar HPP593,REN001,REN001 ; HPP593
Mavodelpar (REN001), a selective PPARδ agonist, effectively suppresses glomerular injury and renal fibrosis. It is utilized in the research of primary mitochondrial myopathies (PMM) and long-chain fatty acid oxidation di...
TP1595 Human Papillomavirus (HPV) E7 protein (49-57) Human Papillomavirus (HPV) E7 protein 49-57
Human Papillomavirus (HPV) E7 protein (49-57) is the H-2d-restricted human papillomavirus (HPV) E749-57 epitope.
T81789 Miromavimab M777-16-3
Miromavimab (M777-16-3) is a monoclonal antibody (mAb) targeting the G-II epitope within the ectodomain of the rabies virus strain ERAGP [1].
T11951 Mavoglurant racemate AFQ-056 racemate Others
Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. Mavoglurant (racemate) is the racemate of mavoglurant.
T61181 Pentagamavunon-1
Pentagamavunon-1 (PGV-1) is an oral Curcumin analog that effectively induces apoptosis through multiple molecular mechanisms. It primarily targets and inhibits key angiogenic factors, including cyclooxygenase-2 (COX-2) a...
TP2183 Large T antigen - rhesus polyomavirus 560-568 Others
Large T antigen - rhesus polyomavirus 560-568 has a peptide sequence of Ser-Glu-Phe-Leu-Leu-Glu-Lys-Arg-Ile. T antigen is required for viral DNA replication, transcription, and virion assembly.
TMIH-0435 Pimavanserin-d3
Pimavanserin-d3 is a deuterated compound of Pimavanserin. Pimavanserin has a CAS number of 706779-91-1. Pimavanserin(ACP-103) is an effective and specific 5-HT2A receptor inverse agonist (mean pIC50: 8.7, in the cell-bas...

Recombinant Proteins

Species：
MPyV (3)
BKPyV (2)
HaPyV (1)
Human (1)
JCPyV (1)
Expression System：
E. coli (7)
Baculovirus Insect Cells (1)
Tag：
C-6xHis (2)
N-10xHis, C-Myc (2)
N-6xHis (2)
N-10xHis (1)
N-GST (1)
Cat No. Product Name Species Expression System
TMPY-03399 KLHL2 Protein, Human, Recombinant (GST) Human E. coli
KLHL2 (Kelch Like Family Member 2) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. KLHL2 contains 1 BTB (POZ) domain and 6 Kelch repeats. It is widely expressed in the brain, esophagu...
TMPH-02984 Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (His) MPyV Baculovirus Insect Cells
Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 42.5 kDa and the accession number is P24595.
TMPH-00201 BK polyomavirus (BKPyV) VP2 Protein (His) BKPyV E. coli
Isoform VP2 is a structural protein that resides within the core of the capsid surrounded by 72 VP1 pentamers. Participates in host cell receptor binding together with VP1. Following virus endocytosis and trafficking to ...
TMPH-02986 Murine polyomavirus (MPyV) (strain Kilham) VP2 Protein (His) MPyV E. coli
Murine polyomavirus (MPyV) (strain Kilham) VP2 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.4 kDa and the accession number is P24596.
TMPH-00789 Hamster polyomavirus (HaPyV) VP1 Protein (His & Myc) HaPyV E. coli
Forms an icosahedral capsid with a T=7 symmetry and a 40 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins. Interacts with sialic acids on...
TMPH-02985 Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (E. coli, His) MPyV E. coli
Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (E. coli, His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 42.4 kDa and the accession number is P24595.
TMPH-00200 BK polyomavirus (BKPyV) VP1 Protein (His & Myc) BKPyV E. coli
BK polyomavirus (BKPyV) VP1 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 45.1 kDa and the accession number is P03088.
TMPH-02365 JC polyomavirus (JCV) Minor capsid protein VP2 (His) JCPyV E. coli
Isoform VP2 is a structural protein that resides within the core of the capsid surrounded by 72 VP1 pentamers. Participates in host cell receptor binding together with VP1. Following virus endocytosis and trafficking to ...
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