Search Result

Search Results for " il-21 "

Targets

Glucocorticoid Receptor Others Interleukin

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T4602	Hydrocortisone hemisuccinate	Hydrocortisone 21-he,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate	Glucocorticoid Receptor , Others , Interleukin
	Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent.		Glucocorticoid Receptor , Others , Interleukin
T6668	SGC-CBP30		Epigenetic Reader Domain , Histone Acetyltransferase
	SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).		Epigenetic Reader Domain , Histone Acetyltransferase
T7123	AMG-47a		VEGFR , p38 MAPK , JAK , Src
	AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protei...		VEGFR , p38 MAPK , JAK , Src
T77052	Latikafusp
	Latikafusp (AMG 256), a bifunctional fusion protein, combines a PD-1-targeting antibody with an IL-21 mutein, facilitating IL-21 pathway stimulation in PD-1+ cells. It aims to enhance and sustain the functionality of cyt...
T63558	IRAK4-IN-21
	IRAK4-IN-21 is a selective, orally active, potent IRAK4 inhibitor that acts on IRAK4 (IC50: 5 nM) and TAK1 (IC50: 56 nM). IRAK4-IN-21 exhibits potent inhibition of IL-23 production with an IC50 value of 0.17 μM. can be ...
T76914	Avizakimab
	Avizakimab (BOS161721), a humanized IgG1 monoclonal antibody, specifically targets interleukin-21 [1].
T78175	JAK-IN-25		JAK
	JAK-IN-25 (compound 19), a potent JAK inhibitor, exhibits IC50 values of 6 nM for TYK2, 21 nM for JAK1, 8 nM for JAK2, and 1051 nM for JAK3. It also demonstrates an IC50 of 28 nM against human whole blood IL-12 (HEB IL-1...		JAK
T63559	IRAK4-IN-22
	IRAK4-IN-22 is a selective, orally active, potent IRAK4 inhibitor that acts on IRAK4 (IC50: 3 nM) and TAK1 (IC50: 17 nM). IRAK4-IN-21 exhibits potent inhibition of IL-23 production with an IC50 value of 0.10 μM. IRAK4-IN...
T73149	HPK1-IN-33
	HPK1-IN-33 (compound 21), a Hematopoietic Progenitor Kinase 1 (HPK1) inhibitor, exhibits a high potency with a K_i of 1.7 nM. It effectively inhibits IL-2 production, demonstrating EC_50 values of 286 nM in Jurkat WT cel...
T35836	PMX-205 (trifluoroacetate salt)
	PMX-205 is a cyclic hexapeptide that acts as a potent antagonist of C5a receptor (C5aR; IC50= 31 nM).1It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma.2,3...

Compounds

Hydrocortisone hemisuccinate

T4602

Synonym: Hydrocortisone 21-he,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate

Target: Glucocorticoid Receptor, Others, Interleukin

SGC-CBP30

T6668

Synonym:

Target: Epigenetic Reader Domain, Histone Acetyltransferase

AMG-47a

T7123

Synonym:

Target: VEGFR, p38 MAPK, JAK, Src

PMX-205 (trifluoroacetate salt)

T35836

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T38838	QS-21	Stimulon,QS-21
	QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, Q...

Natural Products

QS-21

T38838

Synonym: Stimulon,QS-21

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01963	IL-21 Protein, Human, Recombinant	Human	E. coli
	IL-21 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.6 kDa and the accession number is Q9HBE4-1.
TMPY-02806	IL-21 Protein, Mouse, Recombinant	Mouse	E. coli
	IL-21 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.3kDa and the accession number is Q9ES17.
TMPJ-01316	IL-21 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Interleukin-21(IL-21) is an approximately 14 kDa cytokine which belongs to the IL-15/IL-21 family. Mature mouse IL-21 shares 66%,59%, 58%, and 88% aa sequence identity with mature canine, human, rabbit, and rat IL-21, re...
TMPK-01172	IL-21 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	E. coli
	Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cytokines. It has been implicated in many immunological process...
TMPK-00043	IL-21 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	E. coli
	Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cytokines. It has been implicated in many immunological process...
TMPJ-01337	IL-21R Protein, Mouse, Recombinant (aa 20-236, His)	Mouse	HEK293 Cells
	Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. IL-21R is expressed mainly on B cells, NK cells, and activated T cells, but is also f...
TMPK-00668	IL-21R Protein, Cynomolgus, Recombinant (aa 41-254, His)	Cynomolgus	HEK293 Cells
	IL-21 and IL-21R were highly expressed in the lesional skin and peripheral blood of psoriasis patients. IL-21 promoted CD4 T cells proliferation and Th17 cells differentiation and inhibiting Treg cells differentiation by...
TMPY-02809	IL-21 Protein, Canine, Recombinant	Canine	E. coli
	IL-21 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and the accession number is Q6L7I9.
TMPY-03585	IL-21 Protein, Rat, Recombinant (His)	Rat	Baculovirus Insect Cells
	IL-21 Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 16.64 kDa and the accession number is A3QPB9.
TMPK-00654	IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (aa 21-362, His)	Cynomolgus	HEK293 Cells
	IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (aa 21-362, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 40.49 kDa and the accession number is G7NYP7.
TMPJ-01347	IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-356, His)	Human	HEK293 Cells
	IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-356, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50-70 KDa and the accession number is Q9NPH3-2.
TMPK-01029	IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (aa 21-367, His)	Mouse	HEK293 Cells
	Interleukin (IL)-1R3 is the co-receptor in three signaling pathways that involve six cytokines of the IL-1 family (IL-1α, IL-1β, IL-33, IL-36α, IL-36β and IL-36γ). In many diseases, multiple cytokines contribute to disea...
TMPK-00331	IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-359, His & Avi), Biotinylated	Human	HEK293 Cells
	IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-359, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is Q9NPH3-1.
TMPJ-00267	IL-5R alpha/CD125 Protein, Human, Recombinant (aa 21-335, His）	Human	HEK293 Cells
	IL-5R alpha/CD125 Protein, Human, Recombinant (aa 21-335, His） is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 45-60 KDa and the accession number is Q01344.
TMPY-03327	IL-6 Protein, Rhesus, Recombinant	Rhesus	E. coli
	IL-6 Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21 kDa and the accession number is A0A1D5QRZ4.
TMPY-01872	IL-28B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-28B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21 kDa and the accession number is A0A7R8C2Z6.
TMPY-02583	IL-1F8 Protein, Mouse, Recombinant	Mouse	E. coli
	IL-1F8 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21 kDa and the accession number is Q9D6Z6.
TMPK-01110	LILRB1/CD85j/ILT2 Protein, Human, Recombinant (aa 116-461, His)	Human	HEK293 Cells
	LILRB1, also known as CD85j and IL-T2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem I...
TMPK-01111	LILRB1/CD85j/ILT2 Domain1 & 2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LILRB1, also known as CD85j and IL-T2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem I...
TMPJ-01361	Siglec-8 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory mo...
TMPY-00351	FGFR2 Protein, Human, Recombinant (beta IIIc, His)	Human	HEK293 Cells
	FGFR2 Protein, Human, Recombinant (beta IIIc, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.2 kDa and the accession number is P21802-21.