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Search Result

Search Results for " il-20 "

Targets

Interleukin

17

Compounds

2

Natural Products

22

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T76747 Fletikumab Anti-IL-20,NN-8226,NNC 0109-0012 Interleukin
Fletikumab (NNC0109-0012) is a monoclonal antibody against IL-20 that is often used as an IL-20 inhibitor.Fletikumab is used in the study of rheumatoid arthritis and psoriasis.
T15757 Limaprost 17α,20-dimethyl-δ2-PGE1,OP1206,ONO1206 PGE Synthase
Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a potent and orally active vasodilator. Limaprost increases blood...
T1846 Y-320 Y320 IL Receptor , Lipase , Interleukin
Y-320 is a new phenylpyrazoleanilide immunomodulator.
T11079 NMI 8739 n-docosahexaenoyl dopamine,Dha-DA conjugate Dopamine Receptor
NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20, MCP-1 and IL-6 release.
T83681 IRBP (1-20) (human, rat) TFA IRBP1-20,Interphotoreceptor Retinoid-Binding Protein (1-20)
Interphotoreceptor retinoid-binding protein (1-20) (IRBP1-20), a dodecapeptide fragment of retinoid-binding protein 3, plays a crucial role in pigment regeneration by facilitating the transport of retinol and retinal bet...
T79170 Immuno modulator-1
Immuno modulator-1 (compound 22) effectively suppresses the secretion of TNFα and IL-2 in human peripheral blood mononuclear cells (hPBMC) with IC50 values of 4.7 nM and 26 nM, respectively. Additionally, this compound e...
T62680 (R)-MLT-985
(R)-MLT-985 (compound 11) is a potent inhibitor of MALT1 protease (IC50: 3 nM). (R)-MLT-985 has an IC50 value of 20 nM for MALT1-dependent IL-2 in Jurkat cells.(R)-MLT-985 inhibits growth and aberrant CARD11/BCL10/MALT1 ...
T35468 (±)19(20)-EDP Ethanolamide
(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively). It is produced through direct epoxygenation of docosahexaenoyl et...
T16434 PAT-048 PDE
PAT-048 is an effective and selective autotaxin inhibitor. PAT-048 reduces dermal fibrosis in vivo. PAT-048 also inhibits IL-6 mRNA expression but displays no effect on autotaxin protein and pulmonary lysophosphatidic ac...
T79733 NLRP3-IN-20 NOD-like Receptor (NLR)
NLRP3-IN-20 (compound 11) is an orally administered inhibitor targeting the NLRP3 inflammasome, exhibiting potent inhibition with an IC50 of 25 nM against IL-1β secretion. It possesses excellent pharmacokinetic propertie...
T83866 LCC-12 formate
LCC-12, a derivative of the biguanide metformin, acts as a copper (II) chelator. It efficiently forms a monomeric bond with copper (II) and at 20 µM, it mitigates hydrogen peroxide-induced oxidation from NADH to NAD+. At...
T83744 Tiger17 TFA H-Trp-Cys-Lys-Pro-Lys-Pro-Lys-Pro-Arg-Cys-His-NH2
Tiger17, a cyclic peptide derivative of tigerinin-RC1 and tigerinin-RC2—antimicrobial peptides from the crab-eating frog (F. cancrivora) skin secretions—enhances HaCaT keratinocytes and human skin fibroblasts proliferati...
T35452 β-Defensin-3 (human) (trifluoroacetate salt)
β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of the periodontopathogenic and ...
T35638 SR 1903
SR 1903 is a modulator of retinoic acid receptor-related orphan receptor γ (RORγ) and liver X receptor (LXR).1 It is an inverse agonist of RORγ (IC50 = ~100 nM in a cell-based reporter assay) and an agonist of LXR. It al...
T37644 Bengamide B
Potent inhibitor of NF-κB activation (IC50 = 85 nM); decreases IκBα phosphorylation. Attenuates LPS-induced nitric oxide production and expression of TNF-α, IL-6 and MCP. Suppresses proliferation of HeLa and HCT116 cell...
T36713 Streptochlorin
Streptochlorin is a bacterial metabolite originally isolated from Streptomyces sp. SF2583 that has diverse biological activities, including antiangiogenic, antiproliferative, and anti-allergic properties. It inhibits TNF...
T36486 Benpyrine
Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 μM. Benpyrine has the poten...
Cat No. Product Name Synonyms Targets
TC0036 Compound Lup-20(29)-en-3-yl acetate IL Receptor , VEGFR , Others , TNF , COX
Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.
T3S1513 (20R)-Protopanaxadiol Protopanaxadiol,20R-Protopanaxadiol,(20R)-Protopanaxdiol Others , Antibacterial
1. (20R)-Protopanaxadiol ((20R)-Protopanaxdiol) has the effect of anti-tumor through increasing the activity of body immunity, inhibiting tumor interstitial microvascular density and its proliferation activity, improving...

Natural Products

Compound Lup-20(29)-en-3-yl acetate
TC0036
Synonym:
Target: IL Receptor, VEGFR, Others, TNF, COX
(20R)-Protopanaxadiol
T3S1513
Synonym: Protopanaxadiol,20R-Protopanaxadiol,(20R)-Protopanaxdiol
Target: Others, Antibacterial

Recombinant Proteins

Species：
Human (16)
Mouse (5)
Rat (1)
Expression System：
HEK293 Cells (14)
E. coli (4)
Baculovirus Insect Cells (3)
P. pastoris (Yeast) (1)
Tag：
C-His (5)
C-hFc (4)
N-His (4)
Tag Free (3)
N-hFc (2)
C-6xHis (1)
C-His-Avi (1)
C-mFc (1)
His (1)
Cat No. Product Name Species Expression System
TMPY-02959 IL-20 Protein, Human, Recombinant Human E. coli
IL-20 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.7 kDa and the accession number is Q9NYY1.
TMPK-00052 IL-20 Protein, Human, Recombinant (His) Human HEK293 Cells
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progres...
TMPK-01198 IL-20 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progres...
TMPK-00051 IL-20 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progres...
TMPK-01197 IL-20 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progres...
TMPY-04239 IL-28A Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
IL-28A Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 21.1 kDa and the accession number is Q8IZJ0.
TMPY-00297 IL-3 Protein, Human, Recombinant(aa 20-152) Human E. coli
IL-3 Protein, Human, Recombinant(aa 20-152) is expressed in E. coli expression system. The predicted molecular weight is 15.2 kDa and the accession number is P08700.
TMPY-00400 IL-17B Protein, Human, Recombinant (hFc) Human Baculovirus Insect Cells
IL-17B Protein, Human, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is Q9UHF5.
TMPY-01054 IL-20RA Protein, Human, Recombinant (His) Human HEK293 Cells
IL-20RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q9UHF4-1.
TMPY-03476 IL-20 Protein, Rat, Recombinant Rat E. coli
IL-20 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.7 kDa and the accession number is P11762.
TMPJ-00194 IL-20RB Protein, Human, Recombinant (hFc) Human HEK293 Cells
Interleukin-20 receptor subunit beta（IL20RB） is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytoki...
TMPY-00280 IL-20RA Protein, Human, Recombinant (hFc) Human HEK293 Cells
IL-20RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52 kDa and the accession number is Q9UHF4-1.
TMPY-05559 IL-20RB Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
IL-20RB Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 23.9 kDa and the accession number is Q6UXL0-1.
TMPK-00060 IL-17B Protein, Mouse, Recombinant (His) Mouse E. coli
IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. IL-17B/...
TMPJ-01337 IL-21R Protein, Mouse, Recombinant (aa 20-236, His) Mouse HEK293 Cells
Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. IL-21R is expressed mainly on B cells, NK cells, and activated T cells, but is also f...
TMPK-01113 IL-31RA Protein, Human, Recombinant (aa 20-519, hFc) Human HEK293 Cells
Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex f...
TMPK-01114 IL-31RA Protein, Human, Recombinant (aa 20-519, His) Human HEK293 Cells
Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex f...
TMPY-04264 SF20 Protein, Human, Recombinant (mFc) Human HEK293 Cells
SF20 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.2 kDa and the accession number is Q969H8.
TMPY-00034 SF20 Protein, Human, Recombinant (His) Human HEK293 Cells
SF20 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is Q969H8.
TMPY-00855 IL-25/IL17E Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
IL-25/IL17E Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is Q8VHH8.
TMPY-00493 IL-19 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the r...
TMPK-00084 IL-17C Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Interleukin‑17C (IL‑17C) is a 15‑20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conser...
IL-20 Protein, Human, Recombinant
TMPY-02959
Species: Human
Expression System: E. coli
IL-20 Protein, Human, Recombinant (His)
TMPK-00052
Species: Human
Expression System: HEK293 Cells
IL-20 Protein, Mouse, Recombinant (His)
TMPK-01198
Species: Mouse
Expression System: HEK293 Cells
IL-20 Protein, Human, Recombinant (hFc)
TMPK-00051
Species: Human
Expression System: HEK293 Cells
IL-20 Protein, Mouse, Recombinant (hFc)
TMPK-01197
Species: Mouse
Expression System: HEK293 Cells
IL-28A Protein, Human, Recombinant (His)
TMPY-04239
Species: Human
Expression System: P. pastoris (Yeast)
IL-3 Protein, Human, Recombinant(aa 20-152)
TMPY-00297
Species: Human
Expression System: E. coli
IL-17B Protein, Human, Recombinant (hFc)
TMPY-00400
Species: Human
Expression System: Baculovirus Insect Cells
IL-20RA Protein, Human, Recombinant (His)
TMPY-01054
Species: Human
Expression System: HEK293 Cells
IL-20 Protein, Rat, Recombinant
TMPY-03476
Species: Rat
Expression System: E. coli
IL-20RB Protein, Human, Recombinant (hFc)
TMPJ-00194
Species: Human
Expression System: HEK293 Cells
IL-20RA Protein, Human, Recombinant (hFc)
TMPY-00280
Species: Human
Expression System: HEK293 Cells
IL-20RB Protein, Human, Recombinant (His)
TMPY-05559
Species: Human
Expression System: Baculovirus Insect Cells
IL-17B Protein, Mouse, Recombinant (His)
TMPK-00060
Species: Mouse
Expression System: E. coli
IL-21R Protein, Mouse, Recombinant (aa 20-236, His)
TMPJ-01337
Species: Mouse
Expression System: HEK293 Cells
IL-31RA Protein, Human, Recombinant (aa 20-519, hFc)
TMPK-01113
Species: Human
Expression System: HEK293 Cells
IL-31RA Protein, Human, Recombinant (aa 20-519, His)
TMPK-01114
Species: Human
Expression System: HEK293 Cells
SF20 Protein, Human, Recombinant (mFc)
TMPY-04264
Species: Human
Expression System: HEK293 Cells
SF20 Protein, Human, Recombinant (His)
TMPY-00034
Species: Human
Expression System: HEK293 Cells
IL-25/IL17E Protein, Mouse, Recombinant (His)
TMPY-00855
Species: Mouse
Expression System: HEK293 Cells
IL-19 Protein, Human, Recombinant (His)
TMPY-00493
Species: Human
Expression System: Baculovirus Insect Cells
IL-17C Protein, Human, Recombinant (His & Avi)
TMPK-00084
Species: Human
Expression System: HEK293 Cells
Cat No. Product Name
L7600 Chemokine Inhibitor Library

59 compounds
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;

Libraries

Chemokine Inhibitor Library
L7600
Compounds: 59
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