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Search Results for " her3 "

Targets

16

Compounds

25

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T13841 PROTAC Her3-binding moiety 1 Others
PROTAC Her3-binding moiety 1 is a Her3 Ligand for PROTAC.
T77976 PROTAC Her3 Degrader-8 PROTACs
PROTAC Her3 Degrader-8 (Compound PP2) is a proteolysis targeting chimera (PROTAC) capable of degrading the Her3 protein in vitro and within cellular assays, with potential to investigate diseases modulated by HER family ...
T77910 Patritumab deruxtecan U3-1287,HER3-DXd
Patritumab deruxtecan (HER3-DXd), an antibody-drug conjugate (ADC), comprises a fully human anti-HER3 IgG1 monoclonal antibody, Patritumab, linked to a topoisomerase I inhibitor payload through a tetrapeptide-based cleav...
T17182 TX1-85-1 EGFR
TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling. TX1-85-1 is an irreversible Her3 inhibitor (IC50: 23 nM). TX1-85-1 is also the first selective Her3 ligand, which forms a cova...
T76796 Patritumab U3-1287,AMG-888 ERK , EGFR , Akt , HER
Patritumab (U3-1287) is an anti-HER3 monoclonal antibody with potential antitumor activity and inhibits phosphorylation of EGFR, HER2, HER3, ERK, and AKT.Patritumab promotes apoptosis and inhibits proliferation in non-sm...
T72075 HyT36
HyT36 is a small molecule hydrophobic tag that selectively destabilizes and promotes the degradation of fusion proteins and the pseudokinase Her3. HyT36 can treat cells expressing erht induced acutely.
T7819 TAS0728 EGFR , HER
TAS0728 is a HER2 inhibitor, with antitumor activity
T29024 TX2-121-1 TX 21211,TX 2-121-1
TX2-121-1 targets HER3 for proteasome-mediated degradation to inhibit HER3-dependent signalling and growth.
T77047 Izalontamab
Izalontamab (SI-B001), a bispecific monoclonal antibody with high selectivity for the EGFR/HER3 heterodimer, targets both EGFR and HER3 receptors. It holds potential for use in cancer research [1].
T77176 Elgemtumab
Elgemtumab (LJM716) is a fully human IgG monoclonal antibody that specifically targets HER3, inhibiting both ligand-dependent and independent HER3 signal transduction and cell proliferation. This function showcases its s...
T81679 Nezutatug EGFR
Nezutatug, an anti-HER3 antibody, serves as a research tool in cancer studies [1].
T5398 BMS 599626 2HCl (873837-23-1(HCl)) AC480 dihydrochloride HER
BMS 599626 2HCl (873837-23-1(HCl)) (AC480 dihydrochloride) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100-fold to Lck, VEGFR2, c-Kit, MET, etc.
T76818 Lumretuzumab
Lumretuzumab, a humanized monoclonal antibody targeting HER3 (ERBB3), serves as a prominent tool for cancer research.
T80604 Duligotuzumab RG 7597,MEHD-7945A EGFR
Duligotuzumab (MEHD-7945A; RG 7597) is a humanized IgG-κ monoclonal antibody targeting Her3 (ErbB3) [1].
T76948 Zenocutuzumab
Zenocutuzumab (MCLA-128) is a humanized bispecific IgG1 antibody with Fab arms that specifically target the extracellular domains of HER2 and HER3 [1].
T76791 Seribantumab
Seribantumab (MM 121), a fully human IgG2 monoclonal antibody, specifically targets HER3, inhibiting the activation of the epidermal growth factor receptor (ErbB) family and its subsequent signaling. This action effectiv...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02365 HER3/ERBB3 Protein, Mouse, Recombinant (His) Mouse HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-00399 HER3/ERBB3 Protein, Human, Recombinant Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-01389 HER3/ERBB3 Protein, Human, Recombinant (His) Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-04956 HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-00246 HER3/ERBB3 Protein, Rhesus, Recombinant Rhesus HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-02477 HER3/ERBB3 Protein, Rhesus, Recombinant (His) Rhesus HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-03024 HER3/ERBB3 Protein, Rat, Recombinant (His) Rat HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPJ-00899 HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) Human Human Cells
Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belon...
TMPY-06658 HER3/ERBB3 Protein, Mouse, Recombinant (hFc) Mouse HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPJ-00413 HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated Human Human Cells
Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belon...
TMPY-06659 HER3/ERBB3 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPK-00453 HER3/ERBB3 Protein, Human, Recombinant (His & Avi) Human HEK293
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and ...
TMPY-03761 HER3/ERBB3 Protein, Human, Recombinant (mFc) Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-00795 HER3/ERBB3 Protein, Human, Recombinant (hFc) Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPK-01280 HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) Cynomolgus,Rhesus macaque HEK293
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and ...
TMPK-00452 HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled Human HEK293
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and ...
TMPY-05753 HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-06631 HER3/ERBB3 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-04541 HER3/ERBB3 Protein, Human, Recombinant (aa 730-1065, His & GST) Human Baculovirus-Insect Cells
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-02478 HER3/ERBB3 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-03023 HER3/ERBB3 Protein, Rat, Recombinant (hFc) Rat HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-06660 HER3/ERBB3 Protein, Rhesus, Recombinant (His & Avi), Biotinylated Rhesus HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-01323 Betacellulin Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the ErbB gene family (ErbB-1/epidermal growth...
TMPY-03569 Betacellulin Protein, Human, Recombinant (hFc) Human HEK293
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the ErbB gene family (ErbB-1/epidermal growth...
TMPY-06597 Betacellulin Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the ErbB gene family (ErbB-1/epidermal growth...
HER3/ERBB3 Protein, Mouse, Recombinant (His)
TMPY-02365
Species: Mouse
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant
TMPY-00399
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (His)
TMPY-01389
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated
TMPY-04956
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Rhesus, Recombinant
TMPY-00246
Species: Rhesus
Expression System: HEK293
HER3/ERBB3 Protein, Rhesus, Recombinant (His)
TMPY-02477
Species: Rhesus
Expression System: HEK293
HER3/ERBB3 Protein, Rat, Recombinant (His)
TMPY-03024
Species: Rat
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)
TMPJ-00899
Species: Human
Expression System: Human Cells
HER3/ERBB3 Protein, Mouse, Recombinant (hFc)
TMPY-06658
Species: Mouse
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated
TMPJ-00413
Species: Human
Expression System: Human Cells
HER3/ERBB3 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPY-06659
Species: Mouse
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (His & Avi)
TMPK-00453
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (mFc)
TMPY-03761
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (hFc)
TMPY-00795
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
TMPK-01280
Species: Cynomolgus,Rhesus macaque
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled
TMPK-00452
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated
TMPY-05753
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06631
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (aa 730-1065, His & GST)
TMPY-04541
Species: Human
Expression System: Baculovirus-Insect Cells
HER3/ERBB3 Protein, Rhesus, Recombinant (hFc)
TMPY-02478
Species: Rhesus
Expression System: HEK293
HER3/ERBB3 Protein, Rat, Recombinant (hFc)
TMPY-03023
Species: Rat
Expression System: HEK293
HER3/ERBB3 Protein, Rhesus, Recombinant (His & Avi), Biotinylated
TMPY-06660
Species: Rhesus
Expression System: HEK293
Betacellulin Protein, Mouse, Recombinant (His & hFc)
TMPY-01323
Species: Mouse
Expression System: HEK293
Betacellulin Protein, Human, Recombinant (hFc)
TMPY-03569
Species: Human
Expression System: HEK293
Betacellulin Protein, Rhesus, Recombinant (hFc)
TMPY-06597
Species: Rhesus
Expression System: HEK293
TargetMol