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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13841 | PROTAC Her3-binding moiety 1 | Others | |
PROTAC Her3-binding moiety 1 is a Her3 Ligand for PROTAC. | |||
T77976 | PROTAC Her3 Degrader-8 | PROTACs | |
PROTAC Her3 Degrader-8 (Compound PP2) is a proteolysis targeting chimera (PROTAC) capable of degrading the Her3 protein in vitro and within cellular assays, with potential to investigate diseases modulated by HER family ... | |||
T77910 | Patritumab deruxtecan | U3-1287,HER3-DXd | |
Patritumab deruxtecan (HER3-DXd), an antibody-drug conjugate (ADC), comprises a fully human anti-HER3 IgG1 monoclonal antibody, Patritumab, linked to a topoisomerase I inhibitor payload through a tetrapeptide-based cleav... | |||
T17182 | TX1-85-1 | EGFR | |
TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling. TX1-85-1 is an irreversible Her3 inhibitor (IC50: 23 nM). TX1-85-1 is also the first selective Her3 ligand, which forms a cova... | |||
T76796 | Patritumab | U3-1287,AMG-888 | ERK , EGFR , Akt , HER |
Patritumab (U3-1287) is an anti-HER3 monoclonal antibody with potential antitumor activity and inhibits phosphorylation of EGFR, HER2, HER3, ERK, and AKT.Patritumab promotes apoptosis and inhibits proliferation in non-sm... | |||
T72075 | HyT36 | ||
HyT36 is a small molecule hydrophobic tag that selectively destabilizes and promotes the degradation of fusion proteins and the pseudokinase Her3. HyT36 can treat cells expressing erht induced acutely. | |||
T7819 | TAS0728 | EGFR , HER | |
TAS0728 is a HER2 inhibitor, with antitumor activity | |||
T29024 | TX2-121-1 | TX 21211,TX 2-121-1 | |
TX2-121-1 targets HER3 for proteasome-mediated degradation to inhibit HER3-dependent signalling and growth. | |||
T77047 | Izalontamab | ||
Izalontamab (SI-B001), a bispecific monoclonal antibody with high selectivity for the EGFR/HER3 heterodimer, targets both EGFR and HER3 receptors. It holds potential for use in cancer research [1]. | |||
T77176 | Elgemtumab | ||
Elgemtumab (LJM716) is a fully human IgG monoclonal antibody that specifically targets HER3, inhibiting both ligand-dependent and independent HER3 signal transduction and cell proliferation. This function showcases its s... | |||
T81679 | Nezutatug | EGFR | |
Nezutatug, an anti-HER3 antibody, serves as a research tool in cancer studies [1]. | |||
T5398 | BMS 599626 2HCl (873837-23-1(HCl)) | AC480 dihydrochloride | HER |
BMS 599626 2HCl (873837-23-1(HCl)) (AC480 dihydrochloride) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100-fold to Lck, VEGFR2, c-Kit, MET, etc. | |||
T76818 | Lumretuzumab | ||
Lumretuzumab, a humanized monoclonal antibody targeting HER3 (ERBB3), serves as a prominent tool for cancer research. | |||
T80604 | Duligotuzumab | RG 7597,MEHD-7945A | EGFR |
Duligotuzumab (MEHD-7945A; RG 7597) is a humanized IgG-κ monoclonal antibody targeting Her3 (ErbB3) [1]. | |||
T76948 | Zenocutuzumab | ||
Zenocutuzumab (MCLA-128) is a humanized bispecific IgG1 antibody with Fab arms that specifically target the extracellular domains of HER2 and HER3 [1]. | |||
T76791 | Seribantumab | ||
Seribantumab (MM 121), a fully human IgG2 monoclonal antibody, specifically targets HER3, inhibiting the activation of the epidermal growth factor receptor (ErbB) family and its subsequent signaling. This action effectiv... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02365 | HER3/ERBB3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-00399 | HER3/ERBB3 Protein, Human, Recombinant | Human | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-01389 | HER3/ERBB3 Protein, Human, Recombinant (His) | Human | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-04956 | HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-00246 | HER3/ERBB3 Protein, Rhesus, Recombinant | Rhesus | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-02477 | HER3/ERBB3 Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-03024 | HER3/ERBB3 Protein, Rat, Recombinant (His) | Rat | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPJ-00899 | HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) | Human | Human Cells |
Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belon... | |||
TMPY-06658 | HER3/ERBB3 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPJ-00413 | HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated | Human | Human Cells |
Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belon... | |||
TMPY-06659 | HER3/ERBB3 Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPK-00453 | HER3/ERBB3 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and ... | |||
TMPY-03761 | HER3/ERBB3 Protein, Human, Recombinant (mFc) | Human | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-00795 | HER3/ERBB3 Protein, Human, Recombinant (hFc) | Human | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPK-01280 | HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) | Cynomolgus,Rhesus macaque | HEK293 |
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and ... | |||
TMPK-00452 | HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled | Human | HEK293 |
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and ... | |||
TMPY-05753 | HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated | Human | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-06631 | HER3/ERBB3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-04541 | HER3/ERBB3 Protein, Human, Recombinant (aa 730-1065, His & GST) | Human | Baculovirus-Insect Cells |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-02478 | HER3/ERBB3 Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-03023 | HER3/ERBB3 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-06660 | HER3/ERBB3 Protein, Rhesus, Recombinant (His & Avi), Biotinylated | Rhesus | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-01323 | Betacellulin Protein, Mouse, Recombinant (His & hFc) | Mouse | HEK293 |
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the ErbB gene family (ErbB-1/epidermal growth... | |||
TMPY-03569 | Betacellulin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the ErbB gene family (ErbB-1/epidermal growth... | |||
TMPY-06597 | Betacellulin Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the ErbB gene family (ErbB-1/epidermal growth... |