gtp — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T71857	GTP-14564		FLT , Tyrosine Kinases
	GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3. GTP-14564 inhibits the growth of interleukin-3-independent Ba/F1 expressing ITD-FLT3 at 3 μ m, whereas a 30-fold higher concentratio...		FLT , Tyrosine Kinases
T39857	8-Br-GTP	8-Bromoguanosine-5'-triphosphate,8-Br-GTP
	8-Br-GTP, an analog of GTP, functions as both a competitive inhibitor of FtsZ polymerization and GTPase activity (with a K i value of 31.8 μM). Moreover, it is capable of facilitating nucleic acid modification.
T4969	Guanosine 5'-triphosphate trisodium salt	GTP Trisodium salt,5'-GTP trisodium salt	Endogenous Metabolite
	Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of se...		Endogenous Metabolite
T11511	Guanosine-5'-triphosphate disodium salt	5'-GTP disodium salt	Others , Endogenous Metabolite
	Guanosine-5'-triphosphate disodium salt (5'-GTP disodium salt) is an enhancer of myogenic cell differentiation and an energy source for translation and other important cellular processes.		Others , Endogenous Metabolite
T83820	TNP-GTP sodium	TNP-Guanosine 5'-triphosphate
	TNP-GTP, a fluorescent derivative of guanosine 5'-triphosphate (GTP), essential for protein synthesis and gluconeogenesis, exhibits an emission peak at 552 nm when excited at 410 nm in water. Its fluorescence intensity i...
TP2254	GTP-Binding Protein Fragment, G alpha		Others
	Using specific antisera raised against synthetic peptides, we find that three distinct GTP-binding protein alpha subunits remain bound to the plasma membrane even after activation with nonhydrolyzable GTP analog. Trypsin...		Others
T83819	2'-O-Methylguanosine-5'-O-triphosphate sodium	2'-methyl GTP,2'-O-methyl GTP
	2’-O-Methylguanosine-5’-O-triphosphate (2’-methyl GTP) acts as an inhibitor targeting the hepatitis C virus (HCV) non-structural protein 5B (NS5B; with an IC50 of 3.5 µM), and serves as an active metabolite of the prodru...
T83843	2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate sodium	2'(3')-ANT-GTP
	2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate (2'-ANT-GTP) and 3'-ANT-GTP are fluorescent derivatives of GTP that exhibit spontaneous isomerization. 2'(3')-ANT-GTP features an emission peak at 428 nm when excited at 3...
T83814	8-Bromoguanosine-5'-O-triphosphate sodium	8-bromo GTP
	8-Bromoguanosine-5'-O-triphosphate, a derivative of guanosine 5'-triphosphate (GTP) - the energy substrate for protein synthesis and gluconeogenesis, acts as an inhibitor of the E. coli GTPase FtsZ with an inhibition con...
T83836	3'-O-Methylguanosine-5'-O-triphosphate sodium	3'-O-methyl GTP
	3'-O-Methylguanosine-5'-O-triphosphate (3'-O-methyl GTP), a methylated derivative of GTP, serves as a chain termination reagent in synthesizing early RNA polymerase II elongation intermediates.
T83299	5′-Guanylyl methylenediphosphonate sodium	β,γ-Methylene-GTP sodium
	5′-Guanylyl methylenediphosphonate (sodium) serves as a GTP analogue and acts as a specific, competitive inhibitor of the GTP reaction in protein synthesis [1].
T10178	Guanosine 5'-triphosphate trisodium salt hydrate	5'-GTP trisodium salt hydrate	Others
	5'-GTP trisodium salt hydrate, an activator of the signal-transducing G proteins, serves as a precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.		Others
T83834	Sp-Guanosine-5'-O-(1-thiotriphosphate) sodium	Sp-GTP-α-S,GTPαS(Sp),GTPαS(A)
	Sp-Guanosine-5'-O-(1-thiotriphosphate) (Sp-GTP-α-S), an isomer of the sulfur-containing nucleotide derivative GTP-α-S, demonstrates the ability to bind tubulin and facilitate microtubule assembly in cell-free assays at a...
T12979	BI-3406		p38 MAPK , MAPK , Ras
	BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.		p38 MAPK , MAPK , Ras
T7461	2,4-Diamino-6-hydroxypyrimidine	DAHP	Reactive Oxygen Species , NO Synthase
	2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis		Reactive Oxygen Species , NO Synthase
T8756	KRAS inhibitor-9	DUN09716	Apoptosis , Ras
	KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS ...		Apoptosis , Ras
T8211	(±)-Decursinol	3',4'-dihydro-3'-hydroxy-Xanthyletin	Others , Antibacterial
	(±)-Decursinol (3',4'-dihydro-3'-hydroxy-Xanthyletin) is a natural product from Angelica gigas.		Others , Antibacterial
T40192	DGTP	2'-Deoxyguanosine-5'-triphosphate	Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.		Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
T12692	RAS GTPase inhibitor 1		Raf
	RAS GTPase inhibitor 1 is a RAS GTPase inhibitor with potential antitumor activity.		Raf
T38782	Mant-GTPγS
	Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.