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Search Results for " ack1 "

10

Compounds

Cat No. Product Name Synonyms Targets
T3709 XMD8-87 ACK1-B19 Tyrosinase , PPAR
XMD8-87 (ACK1-B19) is a TNK2 inhibitor with activity in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation mutations found in solid tumor types.
T5092 AIM-100 AIM100 ACK
AIM-100 is a Ack1 inhibitor (IC50: 24 nM).
T3196 GNF-7 GNF7 Bcr-Abl , ACK , AChR
GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.
T2641 KRCA-0008 KRCA 0008,KRCA0008 ACK , ALK
KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.
TP1971 Pseudo RACK1
Activator of protein kinase C; attached to cell permeabilization Antennapedia domain vector peptide. Consists of peptide derived from the C2 domain of PKC β linked by a disulfide bridge to the Antennapedia domain vector ...
T68740 NVP-TAC544
NVP-TAC544 is a novel focal adhesion kinase (FAK) inhibitor, potently blocking kinase activity of FAK along with Aurora A, activated Cdc42-associated kinase 1 (ACK1), Met, insulin receptor (IR), TrkA, and IGF-1R.
T2382 Vemurafenib RO5185426,RG7204,PLX4032 Raf , MAPK , ACK , Src , Autophagy
Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently. Vemurafenib exhibits antitumor activity and is used for the treatment of BRAF V600E mutation-positive...
T13564L2 AZ7550 trimesylate salt AZ7550 Mesylate,AZ7550 trimesylate salt (1421373-99-0 free base) MLK
AZ7550 trimesylate salt (AZ7550 Mesylate) is the active metabolite of ositinib, AZ7550 trimesylate salt inhibits IGF1R activity and can be used in the study of non-small cell lung cancer.
T13564 AZ7550 MLK , FAK , EGFR , FLT , Tyrosine Kinases , PYK2 , MNK , IGF-1R , ACK , BTK , ALK , Drug Metabolite
AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
T13564L AZ7550 hydrochloride AZ7550 hydrochloride (1421373-99-0 free base) EGFR , IGF-1R
AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
TargetMol