atf — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T78121	SSM3 tetraTFA hydrate		Others
	SSM3 tetraTFA hydrate is a potent synthetic inhibitor of furin, exhibiting an EC50 of 54 nM and a Ki of 12 nM. It effectively inhibits the furin-dependent cell surface processing of anthrax protective antigen-83 in vitro...		Others
T83679	Parasin I (catfish) TFA
	Parasin I, a peptide fragment derived from the N-terminal region of histone H2A in catfish (P. asotus), plays a critical role in host defense. This antimicrobial peptide is produced through the action of cathepsin D on h...
T82952	ATF3 inducer 1
	ATF3 Inducer 1 is a potent activator of ATF3, enhancing both ATF3 protein and mRNA levels, and exhibits anti-metabolic syndrome (anti-MetS) activity in mice [1].
T21865	BC 11-38		PDE
	BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).		PDE
T11995	Melatonin-d4	N-Acetyl-5-methoxytryptamine D5,Melatonin D5	Others
	Melatonin D5, a deuterium-labeled version of melatonin, is a hormone produced by the pineal gland, known for its role as a selective ATF-6 inhibitor that promotes apoptosis in human hepatoma cells via COX-2 downregulatio...		Others
T63665	EIF2α activator 1
	EIF2α Activator 1 (Compound 40) is a chemical compound that activates the phosphorylation of eukaryotic initiation factor 2 alpha (eIF2α), enhancing the expression of downstream proteins ATF and CHOP. It demonstrates ant...

Compounds

SSM3 tetraTFA hydrate

T78121

Synonym:

Target: Others

Parasin I (catfish) TFA

Synonym: N-Acetyl-5-methoxytryptamine D5,Melatonin D5

Cat No.	Product Name	Synonyms	Targets
T1659	Melatonin	Melatonine,N-Acetyl-5-methoxytryptamine	CaMK , Apoptosis , Mitophagy , Estrogen/progestogen Receptor , Melatonin Receptor , Glutathione Peroxidase , Endogenous Metabolite , ROR , Autophagy
	Melatonin (Melatonine) is a biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin...

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-01164	ATF-3 Protein, Human, Recombinant (His)	Human	E. coli
	ATF3 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-02613	ATF-5 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific respo...
TMPH-03274	ATF-4 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	ATF-4 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.2 kDa and the accession number is Q9ES19.
TMPK-00782	PLAU/uPA Protein, Mouse, Recombinant (His & Avi)	Mouse	HEK293 Cells
	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPY-00904	Urokinase/uPA Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Urokinase/uPA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is A0A024QZM9.
TMPY-02792	GDNF Protein, Human, Recombinant (HEK293)	Human	HEK293 Cells
	GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
TMPJ-00886	ATF1 Protein, Human, Recombinant (His)	Human	E. coli
	Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain, belongs to the bZIP family. It influences cellular physiologic processes by r...
TMPK-00539	PLAU/uPA Protein (active form), Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPK-00274	PLAU/uPA Protein (active form), Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPK-00783	PLAU/uPA Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPY-06970	GDNF Protein, Human, Recombinant	Human	E. coli
	GDNF Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.2 kDa and the accession number is P39905-1.
TMPH-02609	CREBZF Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation...
TMPY-02444	ATF2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-ac...
TMPH-00886	ATF7IP2 Protein, Human, Recombinant (His)	Human	E. coli
	Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the conte...