appa — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T78612	APPA		Apoptosis
	APPA, an aldose reductase inhibitor, demonstrates efficacy in preventing apoptosis and symptoms of Streptozotocin-induced diabetes in rats through inhibition of the polyol pathway. This compound shows promise for researc...		Apoptosis
T26074	Rhizocticin A	Arg-appa
	Rhizocticin A is a potential inhibitor of threonine synthase.
T38438	3-Aminopropylphosphinic acid	3-APPA,CGA147823,CGP27492
	3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA). It acts as a potent and selective agonist of the GABA B receptor.
T6S1780	Protosappanin B	Q-100961,FT-0689654	Apoptosis
	1. Protosappanin B (Q-100961) significantly increases cell viability, inhibits cell apoptosis and up-regulates the expression of growth-associated protein 43. 2. Protosappanin B induces the degradation of p53 protein, vi...		Apoptosis
T32570	Lappaconine	20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol,O(sup 1)-Methyllappaconidine	Others
	Lappaconine (20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol) derivated from norditerpenoid alkaloids.		Others
TJS1779	Protosappanin A	PTA	NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT
	Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IÎºB/NF-ÎºB inflammation signal pathway; it exerts anti-neuroinflammatory ...
T13589	Caesappanin C		Others
	Caesappanin C, extracted from the heartwood of Indonesian Caesalpinia sappan L., shows strong proliferation stimulating activity against the primary osteoblastic cells in vitro.		Others
T2806	Lappaconitine	(+)-Lappaconitine	P2X Receptor , Sodium Channel
	Lappaconitine ((+)-Lappaconitine), isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic.		P2X Receptor , Sodium Channel
T78337	Mouse IgG2a kappa, Isotype Control
	Mouse IgG2a kappa, Isotype Control is an isotype antibody to murine-derived IIgG2a kappa antibody.
TMA1570	Sappanone A		NF-κB , Nrf2
	Sappanone A is a high isoflavanone that exhibits anti-inflammatory effects by modulating Nrf2.Sappanone A attenuates allergic airway inflammation in ovalbumin-induced asthma.		NF-κB , Nrf2
T6560	Lappaconitine hydrobromide	Lappaconite HBr,Allapinine	Others
	Lappaconitine hydrobromide (Allapinine) is a kind of alkaloid extracted from Aconitum sinomontanum Nakai. It has anti-inflammatory effects.		Others
T125353	Apparicine
	Apparicine is a useful organic compound for research related to life sciences and the catalog number is T125353.
T126471	3'-Deoxy-4-O-methylepisappanol
	3'-Deoxy-4-O-methylepisappanol is a useful organic compound for research related to life sciences and the catalog number is T126471.
TN4410	Lappaol C		P-gp , JNK
	Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol C also has potential chemosensitizing activity, it may be candidat...		P-gp , JNK
T73416	BiCAPPA
	BiCAPPA, a pioneering bivalent antiprion ligand, effectively reduces the infectious conformational form of prion protein (PrP Sc) in scrapie-infected cells, achieving this at a concentration (EC 50) of 0.32 μM.
T81758	Mouse IgG2b kappa, Isotype Control
	Mouse IgG2b kappa Isotype Control is a mouse monoclonal antibody serving as an isotype control for mouse IgG2bκ antibody applications.
T78244	Human IgG4 kappa, Isotype Control
	Human IgG4 kappa Isotype Control is a monoclonal antibody serving as an isotype control for the human IgG4κ antibody [1].
T82161	Human IgG1 (D265A) kappa, Isotype Control
	Human IgG1 (D265A) kappa Isotype Control is a chimeric monoclonal antibody derived from both human and mouse, designed to serve as an isotype control for the human IgG1 (D265A)κ antibody.
T78340	Human IgG1 (N297A) kappa, Isotype Control
	Human IgG1 (N297A) kappa Isotype Control is a human-mouse chimeric monoclonal antibody serving as an isotype control specifically for the human IgG1 (N297A)κ antibody.
T78242	Human IgG1 kappa, Isotype Control
	Human IgG1 kappa Isotype Control is a human monoclonal antibody serving as an isotype control specifically for human IgG1κ antibodies [1].