aica — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T21195	AICAR monophosphate	Aica ribonucleotide,AICA riboside,Acadesine 5'-monophosphate,Z-nucleotide	Others
	AICAR monophosphate (Aica ribonucleotide) is a purine precursor with antineoplastic activity and can be used in studies about type 2 diabetes.		Others
T14149	AICAR phosphate	AICA Riboside phosphate,Acadesine phosphate	Mitophagy , NOS , YAP , AMPK
	AICAR phosphate (Acadesine phosphate) is an AMPK activator and inhibitor of autophagy, YAP, and mitophagy, as well as an adenosine analog that regulates glucose and lipid metabolism, and inhibits the production of pro-in...		Mitophagy , NOS , YAP , AMPK
T1477	AICAR	NSC105823,AICA Riboside,Acadesine,AICAR (Acadesine)	Mitophagy , YAP , AMPK , Autophagy
	AICAR (NSC105823) is an AMP-activated protein kinase activator which is used for the treatment of acute lymphoblastic leukemia and may have applications in treating other disorders such as diabetes.		Mitophagy , YAP , AMPK , Autophagy
T1705	5-Amino-3H-imidazole-4-Carboxamide	4-Amino-5-imidazolecarboxamide,AICA,5-Aminoimidazole-4-carboxamide	Endogenous Metabolite
	5-Amino-3H-imidazole-4-Carboxamide (AICA) is an imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparat...		Endogenous Metabolite
T21194	Orazamide	Aicorat dihydrate,Aica orotate dihydrate,Orazamide dihydrate,Aicamin dihydrate
	Orazamide may be useful to treat chronic hepatitis and various skin diseases.
TN3848	Dihydrobaicalein		PLK
	Dihydrobaicalein is a natural product from Scutellaria baicalensis, a PLK1 inhibitor (IC50:6.3 μM).Dihydrobaicalein inhibits VRK2 and PLK2.		PLK
TN1427	Baicalin methyl ester		Anti-infection
	Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT).		Anti-infection
T2858	Baicalein	5,6,7-Trihydroxyflavone	Ferroptosis , Influenza Virus , ROS , Xanthine Oxidase
	Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.		Ferroptosis , Influenza Virus , ROS , Xanthine Oxidase
T2775	Baicalin	Baicalein 7-O-β-D-glucuronide	NF-κB , HIV Protease , GABA Receptor , Autophagy
	Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV properties.		NF-κB , HIV Protease , GABA Receptor , Autophagy
T69385	Baicalein monohydrate
	Baicalein monohydrate is an inhibitor of 12-lipoxygenase, leukotriene biosynthesis and release of lysosomal enzymes. It also inhibits cellular Ca2+ uptake and mobilization and adjuvant-induced arthritis.
TN3268	8,8''-Bibaicalein		Others
	8,8''-Bibaicalein is a natural product from Scutellaria baicalensis.		Others
T16837	SAICAR		Others
	SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner (EC50: 0.3 mM).		Others
T82558	Dihydrobaicalin
	Dihydrobaicalin, a flavonoid glycoside, is isolated from the American skullcap (Scutellaria lateriflora L.) [1].
TN3480	Baicalein 7-O-beta-D-ethylglucuronide		Others
	Baicalein 7-O-beta-D-ethylglucuronide is a natural product from Scutellaria baicalensis Georgi.		Others
TN1426	Baicalein 6-O-glucoside		Others
	Baicalein 6-O-glucoside is a natural product from Thymus serpyllum L.		Others
T4901	5'-Guanylic acid disodium salt	Guanosine 5'-monophosphate disodium salt,GMP-5	Others , Endogenous Metabolite
	5'-Guanylic acid disodium salt (GMP-5) belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular, L-Glutamic acid and guanosine monophosphate can be biosynthesized from xanthy...		Others , Endogenous Metabolite
T19346	5'-Guanylic acid	5'-guanosine monophosphate,5'-GMP	Endogenous Metabolite
	5'-Guanylic acid (5'-guanosine monophosphate) is involved in several metabolic disorders, including AICA-ribosiduria pathway, adenosine deaminase deficiency,adenine phosphoribosyltransferase deficiency (aprt), and the 2-...		Endogenous Metabolite