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AICAR monophosphate (Alias: Z-nucleotide, AICA riboside, Aica ribonucleotide, Acadesine 5'-monophosphate)

Catalog No. T21195 Copy Product Info
Purity: 99.8%
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AICAR monophosphate (Aica ribonucleotide) is a purine precursor with antineoplastic activity and can be used in studies about type 2 diabetes.

AICAR monophosphate

Copy Product Info
😃Good
Catalog No. T21195
Alias Z-nucleotide, AICA riboside, Aica ribonucleotide, Acadesine 5'-monophosphate

AICAR monophosphate (Aica ribonucleotide) is a purine precursor with antineoplastic activity and can be used in studies about type 2 diabetes.

AICAR monophosphate
Cas No. 3031-94-5
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$85In StockIn Stock
5 mg$189In StockIn Stock
10 mg$303In StockIn Stock
25 mg$513In StockIn Stock
1 mL x 10 mM (in DMSO)$197In StockIn Stock
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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Purity:99.8%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
AICAR monophosphate (Aica ribonucleotide) is a purine precursor with antineoplastic activity and can be used in studies about type 2 diabetes.
SynonymsZ-nucleotide, AICA riboside, Aica ribonucleotide, Acadesine 5'-monophosphate
Chemical Properties
Molecular Weight338.21
FormulaC9H15N4O8P
Cas No.3031-94-5
SmilesNC=1N(C=NC1C(N)=O)[C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O
Relative Density.2.30 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 27.5 mg/mL (81.31 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9567 mL14.7837 mL29.5674 mL147.8371 mL
5 mM0.5913 mL2.9567 mL5.9135 mL29.5674 mL
10 mM0.2957 mL1.4784 mL2.9567 mL14.7837 mL
20 mM0.1478 mL0.7392 mL1.4784 mL7.3919 mL
50 mM0.0591 mL0.2957 mL0.5913 mL2.9567 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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