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Search Results for " 5-ht,antidepressant "

20

Compounds

Cat No. Product Name Synonyms Targets
T21946 BIMU 8 5-HT Receptor
BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.
TQ0311 GSK163090 Dopamine Receptor , 5-HT Receptor
GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
T22453 Venlafaxine Wy 45030 Serotonin Transporter
Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia.
T16421 P-MPPI hydrochloride 5-HT Receptor
p-MPPI hydrochloride is a selective antagonist of 5-HT1A receptor, and has antidepressant and anxiolytic-like effects.
T3933 Jatrorrhizine Yatrorizine,neprotin MAO , 5-HT Receptor , Antibacterial , AChE
Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits mo...
T0162 Quetiapine ICI204636,Quetiapin Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antago...
T19931 Gentisein NSC 329491,NSC329491,NSC-329491 Serotonin Transporter
Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7 µM[1][2].
T21013 Clomipramine Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina 5-HT Receptor
Clomipramine (Clomicalm) is a tricyclic antidepressant (TCA). It is used for the treatment of the panic disorder, obsessive-compulsive disorder, major depressive disorder, and chronic pain. It may decrease the risk of su...
T0255 Clomipramine hydrochloride Clomipramine HCl,Anafranil Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine , GST
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demeth...
T0137 Mirtazapine 6-Azamianserin,Org3770 Dopamine Receptor , 5-HT Receptor , Opioid Receptor , Adrenergic Receptor , Histamine Receptor
Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and h...
T6241 Quetiapine hemifumarate Quetiapine Fumarate,ICI-204636 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression.
T4912 Jatrorrhizine chloride Yatrorhizine chloride,Neprotine chloride Others , 5-HT Receptor , OCT , Antibacterial , AChE
Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h...
T26375 (S)-Amisulpride Esamisulpride,(S) Amisulpride,SEP-4199 Dopamine Receptor , 5-HT Receptor
(S)-Amisulpride ((S) Amisulpride) (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a Ki of 900 nM. (S)-Amisulpride has antipsychotic and antidepr...
T1445 Agomelatine Thymanax,S-20098,Valdoxan Melatonin Receptor , 5-HT Receptor
Agomelatine (Valdoxan) is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression.
T0472 Venlafaxine hydrochloride Venlafaxine HCl,Wy 45030 hydrochloride 5-HT Receptor , Serotonin Transporter
Venlafaxine hydrochloride (Wy 45030 hydrochloride) is a cyclohexanol and phenylethylamine derivative that functions as a SEROTONIN AND NORADRENALINE REUPTAKE INHIBITOR (SNRI) and is used as an ANTIDEPRESSIVE AGENT.
T4274 Melitracen hydrochloride Thymeol hydrochloride,Melixeran Dopamine Receptor , 5-HT Receptor
Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.
T22051 BU 224 hydrochloride Imidazoline Receptor
BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.
T4297 Flibanserin BIMT-17BS,Girosa,BIMT-17 Dopamine Receptor , 5-HT Receptor
Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor serum aminotransferase elevations during treatment but has n...
T3275 Nefazodone hydrochloride Dutonin,MJ-13754-1,Serzone,BMY-13754-1,BMY-13754 5-HT Receptor , Adrenergic Receptor
Nefazodone hydrochloride (Serzone) is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder.
T1483 Citalopram hydrobromide Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,Citalopram HBr 5-HT Receptor , Serotonin Transporter , Autophagy
Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system...

Compounds

BIMU 8
T21946
Synonym:
Target: 5-HT Receptor
GSK163090
TQ0311
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
Venlafaxine
T22453
Synonym: Wy 45030
Target: Serotonin Transporter
p-MPPI hydrochloride
T16421
Synonym:
Target: 5-HT Receptor
Jatrorrhizine
T3933
Synonym: Yatrorizine,neprotin
Target: MAO, 5-HT Receptor, Antibacterial, AChE
Quetiapine
T0162
Synonym: ICI204636,Quetiapin
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR, Histamine Receptor
Gentisein
T19931
Synonym: NSC 329491,NSC329491,NSC-329491
Target: Serotonin Transporter
Clomipramine
T21013
Synonym: Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina
Target: 5-HT Receptor
Clomipramine hydrochloride
T0255
Synonym: Clomipramine HCl,Anafranil
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine, GST
Mirtazapine
T0137
Synonym: 6-Azamianserin,Org3770
Target: Dopamine Receptor, 5-HT Receptor, Opioid Receptor, Adrenergic Receptor, Histamine Receptor
Quetiapine hemifumarate
T6241
Synonym: Quetiapine Fumarate,ICI-204636
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Jatrorrhizine chloride
T4912
Synonym: Yatrorhizine chloride,Neprotine chloride
Target: Others, 5-HT Receptor, OCT, Antibacterial, AChE
(S)-Amisulpride
T26375
Synonym: Esamisulpride,(S) Amisulpride,SEP-4199
Target: Dopamine Receptor, 5-HT Receptor
Agomelatine
T1445
Synonym: Thymanax,S-20098,Valdoxan
Target: Melatonin Receptor, 5-HT Receptor
Venlafaxine hydrochloride
T0472
Synonym: Venlafaxine HCl,Wy 45030 hydrochloride
Target: 5-HT Receptor, Serotonin Transporter
Melitracen hydrochloride
T4274
Synonym: Thymeol hydrochloride,Melixeran
Target: Dopamine Receptor, 5-HT Receptor
BU 224 hydrochloride
T22051
Synonym:
Target: Imidazoline Receptor
Flibanserin
T4297
Synonym: BIMT-17BS,Girosa,BIMT-17
Target: Dopamine Receptor, 5-HT Receptor
Nefazodone hydrochloride
T3275
Synonym: Dutonin,MJ-13754-1,Serzone,BMY-13754-1,BMY-13754
Target: 5-HT Receptor, Adrenergic Receptor
Citalopram hydrobromide
T1483
Synonym: Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,Citalopram HBr
Target: 5-HT Receptor, Serotonin Transporter, Autophagy
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TargetMol