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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11039 | Didesethyl chloroquine | Bisdesethylchloroquine | Drug Metabolite |
Didesethyl chloroquine (Bisdesethylchloroquine) is an effective myocardial inhibitor. Didesethyl chloroquine (Bisdesethylchloroquine) is the main metabolite of the antimalarial drug chloroquine. | |||
T0194 | Chloroquine phosphate | Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate | SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy |
Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs). | |||
T8689 | Chloroquine | CQ | SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy |
Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the treatment of malaria and rheumatoid arthritis. Chloroquine als... | |||
T11001L1 | N-Desethyl Chloroquine Hydrochloride | (±)-Desethylchloroquine 2HCl | |
N-Desethyl Chloroquine Hydrochloride ((±)-Desethylchloroquine 2HCl) is a desethylchloroquine derivative. desethylchloroquine competitively inhibits cyp2d1 /6-mediated reactions in vitro and in vivo. | |||
T0194L2 | Chloroquine dihydrochloride | Chloroquine HCl,NSC 14050,Aralen hydrochloride,NSC14050,Chloroquine hydrochloride,Aralen HCl,NSC-14050 | |
Chloroquine is a medication preventing and treating malaria in areas where malaria is known to be sensitive to its effects. It is also sometimes used for amebiasis that is occurring outside the intestines, rheumatoid art... | |||
T11001L | Desethyl chloroquine diphosphate | Others | |
Desethyl chloroquine diphosphate is the main deethyl metabolite of chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Chloroquine diphosphate has anti-plasma activity. | |||
T11001 | Desethyl chloroquine | Monodesethylchloroquine,N-deethylchloroquine | Parasite |
Desethyl chloroquine (Monodesethylchloroquine) is a major metabolite of Chloroquine which is a TLR inhibitor. Desethyl chloroquine shows antiplasmodic activity. | |||
T83602 | (+)-Chloroquine | ||
(+)-Chloroquine, an aminoquinoline drug, inhibits the in vitro terminal glycosylation of angiotensin-converting enzyme 2 (ACE-2) [1]. | |||
TMIH-0146 | Chloroquine-d5 | ||
Chloroquine-d5 is a deuterated compound of Chloroquine. Chloroquine has a CAS number of 54-05-7. Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is an antimalarial and anti-inflammatory ... | |||
TN3790 | Dehydroabietinol | Pomiferin A,Dehydroabietyl alcohol | Antifection |
Dehydroabietinol (Pomiferin A) inhibits growth of chloroquine-sensitive as well as chloroquine-resistant strains of Plasmodium falciparum cultivated in erythrocytes in vitro (IC 50 26-27 microM). | |||
T3682 | (-)-Catechin gallate | (-)-Catechin 3-O-gallate,(-)-Catechin 3-gallate | Others , COX |
(-)-Catechin gallate ((-)-Catechin 3-O-gallate) displays inhibition of 6PGD, IDH. (-)-Catechin gallate ((-)-Catechin 3-O-gallate) displays inhibition of human Beta-secretase. (-)-Catechin gallate ((-)-Catechin 3-O-gallat... | |||
T15276 | Ferroquine | SSR97193,Ferrochloroquine | Others |
Ferroquine (Ferrochloroquine) is a ferrocenyl analogue of Chloroquine with antimalarial activity. Ferroquine induces oxidative stress and the subsequent destruction of the membrane, resulting in parasiticidal effect on P... | |||
T10835L1 | Cletoquine hydrochloride | Cletoquine hydrochloride( 4298-15-1 Free base) | Influenza Virus , Parasite |
Cletoquine hydrochloride is a major active metabolite of Hydroxychloroquine. Cletoquine hydrochloride is a Chloroquine derivative and exhibits the ability to against the chikungunya virus (CHIKV). Cletoquine hydrochlorid... | |||
TN1905 | Magnolioside | Antifection | |
Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a moderate antibacterial activity against Staphylococcus aureus CI... | |||
T0392 | Artemisinin | Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,Artemisinine | HCV Protease , Ferroptosis , Akt , Parasite |
Artemisinin (Qinghaosu) is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of malarial organisms, including chloroquine-resistant Plasmodium ... | |||
T3437 | Lys05 | Lys01 trihydrochloride | lysosomal autophagy , Autophagy |
Lys05, or Lys01 trihydrochloride, is a potent, water soluble lysosomal autophagy inhibitor. Lys05 is a previously undescribed dimeric chloroquine which more potently accumulates in the lysosome and blocks autophagy compa... | |||
T3266 | Lumefantrine | Benflumetol,dl-Benflumelol | Others , Parasite , Autophagy |
Lumefantrine (dl-Benflumelol) is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy exerts its effects again... | |||
T20910 | Dibemethine | Dibemetina,DBMA,AI3-26795,Dibemethinum | |
Dibemethine is active against chloroquinone-resistant Plasmodium falciparum by the inhibition of P. falciparum chloroquine-resistance transporter (PfCRT). | |||
TN1442 | Betulinic acid methyl ester | Antifection | |
Betulinic acid methyl ester showed antiplasmodial activity against chloroquine-resistant Plasmodium falciparum parasites in vitro.It also inhibited B16 2F2 cell proliferation by induction of apoptosis. | |||
TQ0072 | Warangalone | Scandenolone | PKA |
Warangalone is an anti-malarial compound that can inhibit the growth of both strains of parasite 3D7 (chloroquine-sensitive) and K1 (chloroquine-resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively. |