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Betulinic acid methyl ester

Catalog No. TN1442 CAS 2259-06-5

Betulinic acid methyl ester showed antiplasmodial activity against chloroquine-resistant Plasmodium falciparum parasites in vitro.It also inhibited B16 2F2 cell proliferation by induction of apoptosis.

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Betulinic acid methyl ester Chemical Structure

Betulinic acid methyl ester, CAS 2259-06-5

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Storage & Solubility Information

Description	Betulinic acid methyl ester showed antiplasmodial activity against chloroquine-resistant Plasmodium falciparum parasites in vitro.It also inhibited B16 2F2 cell proliferation by induction of apoptosis.
In vitro	These substances showed antiplasmodial activity against chloroquine-resistant Plasmodium falciparum parasites in vitro, with IC(50) values of 9.89, 10.01, 5.99, 51.58, and 45.79 microM, respectively. Mice infected with Plasmodium berghei and treated with betulinic acid acetate had a dose-dependent reduction of parasitemia[1]
Source	Natural Products > Rhamnaceae > Ziziphus

Molecular Weight	470.738
Formula	C31H50O3
CAS No.	2259-06-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Antimalarial activity of betulinic acid and derivatives in vitro against Plasmodium falciparum and in vivo in P. berghei-infected mice.Parasitol Res. 2009 Jul;105(1):275-9.

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Keywords

Betulinic acid methyl ester 2259-06-5 Microbiology/Virology Antifection inhibitor inhibit

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